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Biomedical subjects

H Meyer

Publications and source records attributed to H Meyer.

696 records · Page 39Linked to original sources
PubMedDate not supplied

Omeprazole for peptic ulcer disease in pregnancy.

This report contains the observations of 9 women who received omeprazole for severe reflux disease during different stages of pregnancy. Four patients took omeprazole at the time of conception, and 3 of these patients continued omeprazole therapy without interruption until delivery. One patient discontinued therapy in the 8th week of pregnancy but had to take the drug again from the 28th week to delivery. The other 5 patients started therapy in weeks 24, 30, 33, 34 and 36 of pregnancy because of bleeding in 2 patients and unbearable H2 receptor refractory reflux symptoms in the other 3 patients. All patients were carefully monitored. In all cases omeprazole was well tolerated. No severe side effects were observed in any of the mothers or their newborns. No malfunctions or malformations were observed in the newborns. Follow-up of the children between 2 and 12 years showed normal development in all children. These data together with the data on 8 such pregnancies published by other authors suggest that omeprazole is safe when given during pregnancy at whatever phase.

Adult↗
PubMedDate not supplied

Human immunodeficiency virus cannot productively infect freshly cultured human cartilage cells.

The use of cartilage allografts is being discussed because of the possible transmission of the human immunodeficiency virus (HIV). To further delineate the possibility for an HIV infection of cartilage cells the susceptibility and permissivity of normal human chondrocytes to HIV-1 was assessed in culture. Isolated cartilage cells were incubated during 30 days with the HIV, testing the production of viral p24 antigens and the formation of particle-bound reverse transcriptase (RT) in the supernatant. The H9 cell line was used as positive control. The production of p24 antigen did not occur on chondrocytes during the whole culture time. Furthermore, no RT activity was detected throughout the entire experimental period. Our results indicate clearly that HIV was not able to infect cartilage cells under these in vitro conditions, and, conclusively, HIV infection of cartilage in vivo is improbable.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Stained native collagen: interpretation of the small angle X-ray scattering and electron microscopic pictures in terms of the primary structure.

The average axial electron-density distribution of stained collagen fibers derived from X-ray small angle pattern, is shown to be substantially related to the projection of the polar amino acid residues onto the axis of the microfibril taking into consideration the staggering of neighbouring molecules. In order to arrive ultimately at a quantitative representation of the experimental data, an additional periodic fluctuation of the density in direction of the fibril axis is required. The necessity of this regular microphase structure for an understanding of known physical properties of collagen fibers will be indicated.

Amino Acid Sequence↗
PubMedDate not supplied

Genetic evidence of Dobrava virus in Apodemus agrarius in Hungary.

Using nested polymerase chain reaction, we sequenced Dobrava virus (DOB) from the rodent Apodemus agrarius in Hungary. The samples we isolated group with DOB samples previously isolated from A. flavicollis. This grouping may indicate host switching.

Animals↗
PubMedDate not supplied

Exporting expertise.

A number of American health plans have established or invested in HMO- and PPO-type plans in other countries. Although these health plans face many challenges, they're finding that managed care has appeal in foreign markets.

Altruism↗
PubMedDate not supplied

Prospective payment gets legs.

Any change seems like an improvement when it comes to Medicare's current payment system for outpatient care. But a fixed-fee system is largely untested, and hospitals have plenty of questions. Here are some answers.

Ambulatory Care↗