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Biomedical subjects

H Matzkin

Publications and source records attributed to H Matzkin.

104 records · Page 6Linked to original sources
PubMed1987

[Paraneoplastic syndromes in cancer of the bladder. Review of the literature].

The paraneoplastic syndromes are not well known among physicians, especially in connection with the bladder carcinoma. They can be first presentation of the malignancy, or be the early sign of disease recurrency. All paraneoplastic syndromes including bladder carcinoma can be grouped into 3: the endocrine-hormonal, the neuro-musculo-cutaneous and the hematologic-connective tissue groups. We discuss the frequency of presentation of each group, as appearing in the literature.

Humans↗
PubMed1987

Epidemiology of gonorrhea among men in the Israel Defense Forces.

During a 4-year period, gonorrhea was diagnosed in 1,119 male members of the Israel Defense Forces who were 18 to 21 years of age. Asian and North African ethnic origin, fewer years of schooling, and low socioeconomic status were found to be important risk factors. The ABO blood groups were not found to be associated with the occurrence of disease.

Adolescent↗
PubMed1985

A study of the factors influencing tetanus immunity in Israeli male adults.

In Israel the immune status of the adult population is largely unknown, because many adults have immigrated from various countries and have no reliable record of immunisation. The Israel Defence Force has implemented a preventive booster immunisation schedule for all its members. The immunity of the adult male population as well as the factors contributing to it were measured and 77.3% found to have sufficient tetanus antibody for protection. The antibody titres in the 3241 subjects studied were found to depend on age. In the older age groups (45-54 years) over one-third had less than 0.01 IU/ml, but even among those of 21-30 years 14% were 'unprotected', if 0.01 IU/ml is taken as the threshold value. Apart from age, the only other contributing factors identified were the occupation as a civilian, education and the number of years since the last immunisation. In our view, the findings call for an immunisation schedule based in each individual country on population serosurveys.

Adult↗
PubMed1985

Naturally acquired immunity to tetanus toxin in an isolated community.

Literature on natural immunity to tetanus is scarce. We examined antitetanus antibody levels with the enzyme-linked immunosorbent assay in 200 people living in an isolated community and clarified the influence of age and sex on immunity. In 197 subjects, antitoxin antibodies were measured. No sex differences were noted, and 30% had protective levels (above 0.01 IU/ml). The percentage of those considered protected was age dependent.

Adolescent↗
PubMed1985

A measles outbreak in the Israel Defense Forces during the 1982 epidemic.

A large measles epidemic occurred in Israel during late 1982, with more than 8,000 reported cases. We anticipated that the cohort serving in the army would be most affected by that epidemic, as there is no measles vaccination program for susceptible adults in Israel. A surveillance program began immediately, and the Army Health Branch was notified of 2,940 cases. The majority of patients were in the first 3 months of service, which are spent mostly in basic training camps, an ideal setting for a measles outbreak. No differences in age-adjusted rates between the sexes were noted, but there were significantly higher rates of illness among those with higher education (24/1,000 in those who completed high school vs. 17/1,000 in those who did not) and those in the highest socioeconomic class. In the light of these data, we suggest that during the first few years of implementation of measles vaccination, infectivity has become dependent on origin and socioeconomic status.

Adolescent↗
PubMed1984

Accidental tenfold overdose of influenza vaccine: a clinical and serological study.

We analyzed the effects of an accidental tenfold overdose of influenza vaccine that was given to 31 young healthy members of the Israel Defense Forces. A clinical workup and serological tests were performed after the vaccination in order to quantify any side effects or complications and relate them to immunogenicity of the vaccine administered. A small age-matched control group of 20 soldiers of the Israel Defense Forces who received normal doses (0.5 ml) of vaccine was subjected to the same examinations. A low vaccine efficacy was noted with the recommended 0.5-ml dose (7 micrograms of hemagglutinin of each influenza type), shown by low fourfold titer rises. A significantly higher number of fourfold changes was noted, as expected, in the study group that received 5.0 ml. Pre- and postvaccination geometric mean titers (GMT) in the control group for A/Bangkok (H3N2), A/Brazil (H1N1) and B/Singapore rose from 21.42 to 47.56, from 13.89 to 45.74 and from 10.44 to 11.68, respectively. In the study group the elevation was significantly more pronounced, GMT rising from 19.15 to 83.54, from 16.81 to 96.60 and from 10.00 to 18.88, respectively. Some minor reactions, such as headache and general malaise, were observed in both the study and control groups, but were more frequent in the former. No severe immediate or long-term local and systemic side effects were noted in either group. The findings presented emphasize the high safety limits of the vaccine used, but also highlight its poor immunogenicity.

Accidents↗
PubMed1978

The cation composition of the seminal plasma and prostatic fluid and its correlation to semen quality.

The concentrations of calcium, magnesium, and zinc were measured by atomic absorption spectrometry. The concentrations of all three cations were found to be strongly correlated with one another and with acidity (pH). Analysis of the relative concentrations in prostatic fluid, split ejaculates, and whole seminal plasma confirmed an almost exclusively prostatic origin of these cations. Semen quality, as judged by motility, vitality, concentration, and morphology of spermatozoa, was inversely related to cation concentrations. Therefore, we recommend adoption of the measurement of seminal divalent cations as part of the routine andrologic examination.

Body Fluids↗
PubMedDate not supplied

Acute non-B hepatitis in the Israel Defence Forces: comparison of some epidemiologic features before and after the usage of preexposure immune serum globulin prophylaxis.

Large-scale epidemics of non-B (HBsAg-negative) hepatitis have occurred in the Israel Defense Forces prior to post- and preexposure immune serum globulin administration. Presently, hepatitis morbidity rates have stabilized around 1 to 2 per 1,000. Several years after vaccine initiation, a comparison of epidemiological features was made in order to redefine risk groups. Seasonal morbidity, sex, ethnic origin and educational status (as a representative of socioeconomic level) were not different after the preexposure immunization compared to the preimmunization era. Therefore, a more selective immunization is proposed.

Acute Disease↗
PubMedDate not supplied

Sexual function after permanent 125I-brachytherapy for prostate cancer.

We prospectively assessed patients' erectile function (EF) using the International Index of Erectile Function (IIEF) and a global assessment questionnaire (GAQ) following permanent 125I-brachytherapy for localized prostate cancer. Of 378 treated patients, 220 had a minimal 2-y follow-up and 131/220 were sexually active prior to brachytherapy, with an EF domain score of > or = 11 (study group). Patients were allowed sildenafil at any time of the study. The patients' mean EF score, without excluding patients who used sildenafil, dropped within 3 months after brachytherapy, recovered at the end of the first year and remained unchanged for at least up to 2 y after treatment regardless of the addition of neoadjuvant hormone therapy to 125I-brachytherapy. Analysis of the GAQ revealed that 80% of the patients were satisfied with their sexual function up to 3 y after treatment. Any detrimental effect of permanent brachytherapy with or without the addition of hormone therapy on EF is reversible, and recovery is expected at 1 y after treatment in most patients.

Aged↗
PubMedDate not supplied

Sexual dysfunction in women partners of men with erectile dysfunction.

We evaluated 113 female partners of men with erectile dysfunction (ED) attending a sexual dysfunction clinic in order to define sexual dysfunction among these women. In all, 51 (45%) women denied having any sexual dysfunction. The other 62 (55%) responded to questions classifying their complaint(s) according to the international classification of female sexual dysfunction (FSD) in the following topics (40/62, 65%, reported having more than one problem): decreased sexual desire (n=35, 56%), sexual aversion (none), arousal (n=23, 37%) and orgasmic disorders (n=39, 63%), dyspareunia (n=19, 31%), vaginismus (n=3, 5%), and noncoital sexual pain (none). Many female partners of men with ED report having some form of sexual disorder, mostly orgasmic problems and decreased sexual desire. Therefore, for optimal outcome of ED treatment, evaluation and treatment of male and FSD should be addressed as one unit within the context of the couple, and be incorporated into one clinic of sexual medicine.

Erectile Dysfunction↗