[Basic text: brain injuries].
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Biomedical subjects
Publications and source records attributed to H Müller.
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The appearance of the amnestic episode is discussed by presentation of 4 own cases and by means of literature. The amnestic episode is a mental disorder, which exclusively affects short-term memory with a sudden onset and a duration of some hours, seldom up to several days, and often it is connected with a retrograde amnesia. The latter disappears in all cases, but there remains a permanent lack of memory for the time of the episode. Recidivism is rare. Internal, neurological and neurophysiological findings during and after the amnestic episode regularly are normal, at least certainly without characteristic findings. The main age of manifestation lies between the 40th and 70th year of life, there is no priority between women and men. Probably a disturbance of blood flow in the supplying area of the basilaric arteria is responsible, though the proof is still missing.
On the basis of many years of examination and supervision of 26 patients with acute intermittent porphyria three different types of excretion behavior in the urine can be distinguished. 1. After porphyric crises the urinary porphyrin content is completely normalized. 2. Even after the crisis the excretion levels for porphyrins remain very high. 3. The urinary porphyrins return to normal levels but the increases in precursors such as delta-aminolevulinic acid and porphobilinogen still persist. 4. In the diagnosis true acute coproporphyria and increased of excretion of precursors must be differentiated as well as increased coproporphyrin resulting from liver diseases, exogenic, toxic influences and secondary disorders of porphyrin metabolism.
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A case of a 57-years-old caucasian male with unilateral condylar hyperplasia and proven acromegaly is presented.
The RNA of infectious bursal disease virus was reexamined in a detailed analysis. It could be established that its genome consists of two segments of double-stranded RNA. The RNA is RNase resistant and has a sedimentation coefficient of 14S and a buoyant density of 1.62 g/ml. The purine/pyrimidine ratio is nearly 1; the guanine plus cytosine content is 55.3%; the Tm is 95.5 degrees C. The molecular weights of the two double-stranded segments were determined to be 2.2 x 10(6) and 2.5 x 10(6).
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The influence of analog-sedation on pulmonary respiration and cardiovascular circulation caused by the action of pentazocine/flunitrazepam respectively in microsurgical operations under local anesthesia in otolaryngology is investigated in two collectives of patients. The results are presented and the hazards, especially the hypoxemia and its avoidance are discussed.
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In ENT surgery due to the differential anatomy of the operation area, radical tumour surgery, necessary plastic surgery and covering of resulting defects, plus efforts in maintenance and reconstruction of important functions the resulting operations are frequently lengthy. In 27 patients whose operations required longer as 10 hours the problems of anaesthesia and operation were analysed and discussion from various angles. With close teamwork between surgeon and anaestheist in the planning and carrying out of such procedures and in the postoperative care it is possible to eliminate higher risks due to the prolonged operation time. The perioperative mortality rate within a time period of 4 weeks was in our case 0%.
Mouse fibroblast interphase nuclei stained with quinacrine dihydrochloride show distinctive differences in their fluorescent characteristics analogous to those which we have already observed in human and Syrian hamster cells. These patterns reflect the position of any given nucleus within the cell cycle. The brightly fluorescent chromocenters in the mouse nuclei were found to be in absolute aggreement with those stained by the C-banding technique, indicating that they represent centromeric heterochromatin. Furthermore, their number and size per nucleus were shown to vary in relation to the progress of the cell cycle.
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1. By counting the axons per micron 2 on electronmicrographs of cross-sectioned olfactory nerves and multiplying this number by the area of the cross-sectioned nerves, the number of olfactory receptors was determined in 4 breeds of domestic pigeons including homing pigeons. 2. The total number of olfactory receptors varied between 3.0 and 7.4 . 10(6). It significantly depended on the body size of the pigeons. There was no evidence for differences in the number of olfactory receptors between the breeds independent of body size. 3. No differences in the relative size of the olfactory bulbs could be detected between the breeds. 4. The ultrastructure of the olfactory epithelium was basically similar to that of other birds. The covering mucus layer was revealed to be a secretion product of both the olfactory glands of Bowman and the olfactory supporting cells. No differences were observed in the ultrastructure of the olfactory region between the four breeds investigated.
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