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Biomedical subjects

H Lutz

Publications and source records attributed to H Lutz.

At least 199 records · Page 11Linked to original sources
PubMed1985

[Sonography of malignant hemangioendothelioma of the liver].

Malignant haemangioendotheliomas of the liver are very rare mesenchymal tumours. Sonographically, they appear as solitary, although more frequently as multicentric, space-occupying growths with blurred and irregularly delineated outlines; the sonographic image shows both echo-dense structures and structures with a low amount of echoes, or which are even echo-free. Short-term sonographic follow-up examinations point to a tendency to rapid growth and varying echogenicity.

Aged↗
PubMed1985

Quantitation with monoclonal antibodies of Escherichia coli H protein suggests histone function.

The abundance of the histonelike H protein of Escherichia coli (U. Hübscher, H. Lutz, and A. Kornberg, Proc. Natl. Acad. Sci. U.S.A. 77:5097-5101, 1980) was determined by using monoclonal antibodies against H protein, immunoblotting, and homogeneous H protein as a standard. H protein was found to be present at approximately 120,000 monomeric molecules per fast-growing E. coli cell. This amount of H protein corresponds to a ratio of one H protein molecule to approximately 200 base pairs of the bacterial chromosome. Together with previous results, these findings suggest that H protein has histonelike function similar to that of histone protein H2A, its counterpart in the eucaryotic cell.

Antibodies, Monoclonal↗
PubMed1985

Identification of 3-hydroxyanthranilic acid in mixed lymphocyte cultures.

3-Hydroxyanthranilic acid was identified in lymphocyte cultures during allogeneic stimulation. The metabolite and the synthetic product have identical HPLC retention times, fluorescence spectra, fluorescence intensities as a function of pH value and electrochemical behaviour.

3-Hydroxyanthranilic Acid↗
PubMed1985

[Use of computer technology in training assistants in the anesthesia department].

The growing importance of computer technology in the fields of medical diagnosis and monitoring cannot be disputed. Few studies, however, have investigated the usefulness of computers in medical education. The following paper presents a teaching program for novice anaesthesists which helps demonstrate the problem of anaesthetizing high risk patients and conveys general guidelines for preoperative diagnosis and intraoperative monitoring. All data registered can be displayed on several video screens simultaneously. A printout of the guidelines is also available. Initial impressions of the program are presented.

Allied Health Personnel↗
PubMed1984

[Premedication for sonography. Enzyme-paractol in comparison with a placebo].

In a randomized double-blind comparative study involving a total of 50 patients divided into two equal groups, the effects of Enzym-Paractol and placebo on the ultrasonographic representation of internal organs in two planes--pancreatic and paraaortic--were compared. The visualizability was estimated as percentage figures, and revealed an improvement of about 15% for Enzym-Paractol as compared with placebo. With respect to undesired side effects, there was no difference between the two substances.

Adult↗
PubMed1984

[Polypoid lesions of the gallbladder wall].

Modern sonography has led to an increased appraisal of the therapeutic consequences in cases of polypoid lesions of the gallbladder wall. In 30 patients it was attempted to differentiate between cholesterol polyps and polypoid lesions suspect for malignancy. Histologic results and data in the literature induce us to recommend cholecystectomy in solitary lesions of more than 5 mm, combined occurrence with gallstones and in patients beyond the 60th year of life.

Adult↗
PubMed1984

[Clinical follow-up studies of persons with extensive exposure to ultrasound radiation].

To investigate the question as to the possibility of damage being done to the human organism by diagnostic ultrasound--with particular emphasis on the aspect of a possible cumulative effect--we investigated 20 people employed by two companies manufacturing ultrasonic equipment, who had been exposed for between 13.5 and 1,000 hours (average 152 hours) over periods varying between 0.75 and 11 years (average 4.2 years). During the examination, which included a thorough clinical work-up, haematological, laboratory and ultrasonographic investigations, particular attention was paid to the liver and blood, since the liver is usually chosen for demonstration and test purposes, and the blood is always exposed to the effects of ultrasound. We found no evidence of any harmful effect of ultrasound on the human organism, nor were there any tendencies correlated with the period of exposure to be found. A newly detected diabetes mellitus was interpreted as an incidental finding.

Adult↗
PubMed1984

Measurement of urinary 7,8-dihydro-6-hydroxylumazine in healthy and in Ehrlich ascites tumour-bearing mice.

An estimation of 7,8-dihydro-6-hydroxylumazine in urinary samples of mice by high performance liquid chromatography on reversed phase material is presented. Urinary samples are diluted with water and oxidized by iodine. Chromatographic elution is done isocratically using aqueous buffer containing methanol. Effluent 6-hydroxylumazine is monitored by its fluorescence (382 nm excitation, 449 nm emission). The described method can be performed rapidly with satisfactory accuracy and precision. The electrochemical detection of 7,8-dihydro-6-hydroxylumazine was studied additionally. Total values of daily excreted 7,8-dihydro-6-hydroxylumazine of healthy and of Ehrlich ascites tumour-bearing mice were measured.

Animals↗
PubMed1984

[Perspectives in the use of computers in anesthesia].

The remarkable development of computer technology and the early experiments into its clinical use give us cause ot define useful spheres of application and task areas in anaesthesia for this valuable machine. Parallel to this followed the development of computer use in anaesthesia. Here, there are essentially four main areas of application: administration of data, monitoring, teaching, process of decision making. Next to a quite uniform definition of the task areas of a computer, the question of the selection of the suitable computer for the respective requirement cannot be answered in the same uniform way. For the application of computer technology in the practice of anesthesiology it is essential to guarantee not only sufficient safety of data but also a protection from misuse and manipulation. On the whole it is probable that computer technology will take over more and more medical technical tasks especially of the anaesthesia apparatus and evaluate them. An automatic registration of records with combined off-line and on-line recording of measured values represents the logical development of this technology.

Anesthesia↗
PubMed1984

[The anesthesia protocol].

It has long been recognised that it is necessary to document all medical actions. Every anaesthesia is to be documented on an anaesthetic transcript. Such a transcript has various purposes. It serves principally as an adequate patient-support, but also has administrative, statistical, scientific and forensic purposes. The transcript used at the Mannheim Klinikum is a printed form, which, apart from recording intra-operative events, also has room for entering pre- and post-operative test results. The recording of an anaesthetic transcript is an essential part of the duties of the anaesthetist in the clinic. Today, with the application of the most differentiated administrations of narcosis, it would seem that we can no longer do without a properly made anaesthetic transcript.

Anesthesia↗
PubMed1984

[The occurrence of intra- and postoperative cardiovascular and pulmonary complications in relation to the preoperative condition of patients. A prospective study].

700 patients were prospectively studied and their development analysed from date of premedication to 28 days postoperative or date of discharge. Concomitant diseases and intra- and/or postoperative complications were documented. Analysing the patients an increasing frequency of risk classes 3 to 5 depending on age were found. Cardiac disorders were more frequently observed after the age of 41.33% of the observed patients were recompensated in respect to the myocardium, 4.5% suffered from angina pectoris and 1.5% showed clinical signs of cardial insufficiency. ECG abnormalities were registered particularly after the age of 41; nevertheless 2.5% of young patients to the age of 20 showed pathological electrocardiograms (ECG). More than 33% of the patients studied were hypertensive and 15% suffered from concomitant lung or airway diseases. Analysing the complications of the cardiocirculatory system an overall frequency of 70% was found, depending on corresponding side diseases and their underlying therapy. Intraoperative complications of the respiratory system are rare; in the postoperative course they became important and were 3 times more common in patients with lung or airway disorders. We conclude that one may achieve a risk diminution by appreciating the risk and by very careful preoperative examination and therapy.

Adolescent↗