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Biomedical subjects

H Lenz

Publications and source records attributed to H Lenz.

At least 55 records · Page 3Linked to original sources
PubMed1984

[Rhinomanometric measurements during gradual physical exertion in subjects with normal nasal breathing].

28 healthy volunteers, 14 males and 14 females, aged from 18 to 45 years with normal nasal breathing were measured rhinomanometrically after physical exercise on an ergometer bicycle after increase in loads by steps of 25, 50, 75, 100, 125 and 150 watt and also 2, 5 and 10 minutes after physical exercise with 150 watt. V15 (nasal air flow related to 15 mm H2O) was registered. A new rhinomanometer with a Prandtl type tube was employed for measuring a relationship between nasal airflow (V2) and transnasal pressure (delta p) yielding a straight line in the V2-delta p-diagramm using nozzles and active anterior method. An increase of V15 up to 150 watt was measured. The average V15 value of the 28 persons for the total nose without decongestion the nasal mucosa before physical exercise at rest is 0.69 l/s and after physical exercise up to a load of 150 watt 1.09 l/s, so that the increase of V15 is 0.4 l/s. This decongestion effect of the nasal mucosa is twice to three times larger than the decongestion after xylometazolin spray 0.1% (Otriven 0.1%). The medicamentous decongestion effect of V15 = 0.14 l/s is as large as the decongestion effect caused by physical exercise with a load of 25 to 50 watt. A decrease of V15 is measured reaching a normal value within 15 minutes. The rhinomanometrical normal values under physical exercise within a load of 0 to 150 watt of healthy volunteers with normal nasal breathing are readable directly in a V15-watt diagramm for the right and left nasal cavity and the total nose based on the average values of all 28 volunteers. Individual variations of the maximal decongestion effect during physical exercise are discussed.

Adolescent↗
PubMed1984

[Report of experiences in the treatment of 16 cases of severe glycoside poisoning with digitalis antibody fragments (Fab)].

To date, 16 patients with severe glycoside poisoning have been treated with Fab as part of the clinical trial for efficacy and tolerance. The ages of the patients ranged from 4 to 77 years. In 13 cases, the substance was taken with suicidal intent. The following were considered to be indications for the use of Fab: the appearance of life-threatening arrhythmias as high-grade atrioventricular conduction disorders, multifocal ectopic beats, ventricular tachycardia, and relapsing ventricular fibrillation in 5 cases. Serum digoxin concentrations were between 3.8 and 78 ng/ml before the start of treatment. The amount of Fab administered was 240-800 mg, in the majority of cases 480 mg. Regression of the arrhythmias was seen in all patients during or shortly after the Fab infusion. There was a rapid fall in the free digoxin in the serum to levels that were no longer measurable and a marked rise in bound digoxin with a simultaneous intensive excretion of bound digoxin in the urine. Fab therapy is considered to be a major advance in the treatment of severe, previously fatal, glycoside poisoning. No notable side effects were observed, nor were there any allergic reactions to foreign protein.

Acetyldigoxins↗
PubMed1983

[Normal values of nasal airflow measured with a newly developed rhinorheomanometer with modified Prandtle-type tube and linear relations].

A new rhinomanometer with a Prandtl type tube for measuring a square relationship between nasal airflow (V2) and transnasal pressure (delta p) yielding a straight line in the V - delta p - diagram is described. This so called rhinomanogram with straight lines is like an audiogram and gives a direct reading of V in relation to delta p. The active anterior method using nozzles is employed. 337 volunteers 185 females and 152 males aged 9-76 years with normal breathing function of the nose and normal endonasal mirror findings are examined with the above mentioned rhinomanometer. The normal values of nasal airflow in relation to 15 mm H2O in l./sec. (V15) of both nasal cavities before and after shrinkage of the nasal mucosa are measured during inspiration and exspiration. For all age groups, both male and female, the normal value of V15 of the entire nose is 0,67 +/- 0,16 l/sec before and 0.81 +/- 0.17 l/sec after shrinkage of the nasal mucosa. Slight differences in the normal values of the entire nose exist between males and females of different age groups as well as during inspiration and exspiration. V15 in females is 0.63 l/sec before and 0.77 l/sec after shrinkage, whereas V15 in males is 0.73 l/sec before and 0.86 l/sec after shrinkage. With increasing age, both in males and in females, there is slight increase of V15: V15 in the age-group of 9-16 years from 0.58 l/sec before to 0.72 l./sec. after shrinkage; in the age-group of 17-40 years it is 0.66 l./sec. before and 0.80 l./sec. after shrinkage whereas in the age-group of 41-76 years it is 0.75 l./sec. before and 0.88 l./sec. after shrinkage. During inspiration V15 is somewhat lower than during exspiration. Our normal V15-values are compared with all normal values of the nasal airflow mentioned in literature by other authors.

Adolescent↗
PubMed1980

[Kleine-Levin-syndrome (author's transl)].

A report is given on a 18 year old girl with a Kleine-Levin-syndrome, which was studied 4 years after beginning in the menarche. At first there were only attacks of nausea and vertigo. One year later the attacks were combined with hypersomnia for several hours. Remarkable was a minimal overirritability of the right vestibular system and a slight hypersensitivity to touch and pain on the whole right side. Worth mentioning is also a disturbed water balance (retention). A disturbance of the hypothalamic regulation is supposed and methylphenidate-hydrochloride (Rilatin) is commanded for treatment.

Adolescent↗
PubMed1979

Di-, mono- and nonphytanyl triglycerides in the serum: a sensitive parameter of the phytanic acid accumulation in Refsum's disease.

The relative proportions of the diphytanyl, monophytanyl and nonphytanyl triglycerides ("triglyceride pattern"), the phytanic acid content of the triglycerides and the phytanic acid levels in the serum of 3 patients with Refsum's disease (heredopathia atactica polyneuritiformis, phytanic acid storage disease) were estimated by thin-layer chromatography, densitometry and gas chromatography, respectively. The individual triglyceride patterns were clearly dependent on the phytanic acid content of the triglycerides: the more phytanic acid in the triglycerides, the higher the percentage of the diphytanyl and the lower the percentage of the nonphytanyl triglycerides. The monophytanyl triglycerides were also related to the phytanic acid content of the triglycerides, although in a complex manner. The triglyceride pattern can be taken as a parameter of the phytanic acid accumulation in Refsum's disease to be at least as sensitive as the serum phytanic acid level in the biochemical evaluation of the efficiency of the dietary treatment.

Eicosanoic Acids↗
PubMed1979

The element of the irrational at the beginning and during the course of delusion.

Delusion is described from a phenomenological point of view. Based on the observation of 15 cases of delusion over a period of several years and 3 cases described by Japanese and American authors, I have concluded that delusion cannot be understood from a genetic, psychological or sociological standpoint alone. My aim was to discover symptoms which could not be explained by psychodynamic, sociological or other causes. Such symptoms may be called irrational (incomprehensible) symptoms. Their irrationality is analogous to the same symptoms which are described in their autobiographies by two great mystics about their ecstasy. We can see these symptoms in the accounts of Zen Buddhists. These symptoms represent experience of evidence, pseudohallucination, suffering in delusion, a message to do something, loss of awareness of time and space, the polarity of guilt and blessedness following each other in close succession and the feeling of shame. We will better understand delusion if we bear in mind the irrational factor.

Affective Symptoms↗
PubMed1978

Temperature distribution in tissue during laser irradiation.

During irradiation with an Ar+-and Kr+-laser the temperature rise in living and dead tissue was measured in various depths. The contribution of the blood flow to the heat transport during irradiation was found to be small. The influence of the different depths of penetration and backscattering at the blue-green Ar+-and the red Kr+-radiation was investigated. The measurements compared with theory show reasonable agreement for an one-dimensional model below 100 degrees C. The results are discussed with respect to laser application in medicine.

Animals↗
PubMed1978

A laser-endoscope with direct beam coupling.

An optical element for direct laser-beam coupling into the observation optic of a rigid endoscope was developed. Using this coupling element every suitable endoscope can be modified into a laser endoscope which can be used for laser surgery e.g. in ENT and urology. The requirements for the endoscope and the optical coupling element are discussed.

Endoscopes↗
PubMed1978

Polyanomalodontia.

Reported is a case of multiple anomalies in dental morphology. The morphological anomalies comprised macrodontia, multituberculism, invaginations, and single conical molar roots. The gross morphological, radiological, histological and ultrastructural findings are presented and compared to similar forms of multiple anomalies in dental morphology.

Abnormalities, Multiple↗