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Biomedical subjects

H Lauter

Publications and source records attributed to H Lauter.

At least 37 records · Page 2Linked to original sources

The onset of Alzheimer's disease. A longitudinal case study and a trial of new diagnostic criteria.

We had the opportunity to document the onset of presenile Alzheimer's disease in a female patient who presented at a very early stage and was followed for 18 months at close intervals. Disturbances of memory, of intellectual abilities, and of language were the initial symptoms, which caused significant impairment of working performance several months before becoming apparent at home. The clinically evident progression of the disease was confirmed by psychometric tests but was overlooked by cognitive screening batteries and by global severity ratings. In the absence of any signs of brain atrophy, even on repeated X-ray computed tomography, a severe temporoparietal reduction of glucose metabolism was disclosed by positron emission tomography. The typical case demonstrated several imperfections of newly introduced diagnostic criteria in their ability to identify early Alzheimer's disease. Improvements for some of these deficiencies are suggested.

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[Dementia].

This report briefly reviews the clinical diagnosis of dementia, including the most important problems of differential diagnosis. General guidelines of therapy are presented with special reference to the modification of secondary factor which may contribute to the severity of dementia and to psychosocial approaches in the management of patients.

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Diagnosis, differential diagnosis and nosologic classification of the dementia syndrome.

Some clinical aspects of the diagnosis, differential diagnosis, and the nosologic classification of the dementia syndrome are presented. In discussing the definition of the dementia syndrome and its differentation from other organic brain syndromes, the criteria of DSM III are taken into account. Considering the nosological classification of the dementia syndrome particular emphasis is placed on the most frequent diseases in the senium, the Multi-Infarct Dementias (MID) and the primary degenerative dementias (PDD, according to DSM III). The clinical problems in differentiating MID from PDD and Morbus Pick from the dementia of the Alzheimer type in the group of are discussed in more detail.

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Classification of parasuicide by cluster analysis. Types of suicidal behaviour, therapeutic and prognostic implications.

A classification of suicidal behaviour was derived by cluster analysis from descriptive data on parasuicide patients. The grouping was meaningful in terms of clinical interpretation and had both therapeutic and prognostic implications. The sample was broken down into three groups, identified as repeated, serious and non-serious attempts. The repeated attempters had the worst prognosis at 1-year follow-up. When the sample was classified into five groups according to seriousness of the attempts, the repeater and non-serious groups were retained, while the serious attempts were split into three subtypes, which differed on nosological characteristics, treatment disposal and outcome. An excessively high successful suicide rate was found in a small group of elderly attempters.

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[Family groups in Alzheimer's disease: initial experiences and results].

A regular family support group was established within an outpatient clinic for demented elderly patients. At the outset of the group, the relatives knew little about the disease and about the available resources of help, but some were highly experienced in the management of dementia. The group provided information, exchange of experience, practical problem-solving, support in emotional difficulties, and clarification of interpersonal conflicts in the family. The effect of the group showed in decreased feelings of burden and tension in most participants. The present observations suggest that family support groups should be long-termed and that the experts' primary task is to activate and amplify the self-help potential of the caregivers.

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[Treatment of patients following attempted suicide within the scope of a liaison service].

Only few patients after suicide attempt are examined by a psychiatrist. In order to intensify the primary psychiatric care of suicide attempters, a psychiatric liaison scheme was established at an intensive care unit of the Technical University, Munich. The main advantages are: A psychiatrist talks with every suicide attempter; the psychiatrist and the medical staff are better informed about the suicidal act and the personality of the suicide attempter because of close cooperation; there is more time for diagnostic and psychotherapeutic activities; suicide risk diminishes while staying on the medical ward. If a psychiatric liaison scheme cannot be established it should be tried to change ward atmosphere by advising the medical staff and offering emotional support.

Commitment of Persons with Psychiatric Disorders↗