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Biomedical subjects

H Laccourreye

Publications and source records attributed to H Laccourreye.

At least 145 records · Page 8Linked to original sources
PubMed1978

[The prognostic value of the time of progression of symptoms and signs in carcinomas of the pharyngo-larynx (author's transl)].

The authors study the Time of Progression of Symptoms and Signs (TPSS) before diagnosis and treatment in 733 carcinomas of the pharyngo-larynx and 233 carcinomas of the piriform fossa. They show that for a given tumour stage (lymph node: clinical and histological), the longer the TPSS, the better the vital prognosis, the better the local and lymph node prognosis (results statistically significant). By contrast, the TPSS has no influence in the development of metastases nor in the occurrence of second tumour sites. In the opinion of the authors, TPSS, based upon routine questioning is the clinical reflection of cell division and of tumours growth. The treatment of these carcinomas whould be modified in the light of the TPSS. The value of chemotherapy used before surgery and radiotherapy is discussed in carcinomas with a short TPSS, less than 3 months, these being tumours with a rapid course with a particularly unfavourable vital, local and lymphatic prognosis.

Antineoplastic Agents↗
PubMed1978

[Partial surgery of carcinomas of the glottis. Results and prognosis (author's transl)].

The authors present a computerized study of the prognosis of 132 cases of carcinoma of the glottis treated by vertical, partial surgery and seen over a period of 1 to 15 years at the Laennec Hospital. After defining the percentage survival at 3.5 in 10 years, the authors studied the causes of death and showed that, after 5 years, it is still deaths due to malignant recurrence which influenced the vital prognosis. These local, lymphnode and metastatic oncological failures are subsequently analyzed on the basis of clinical, surgical and histological parameters as well as in terms of the course of the disease. Such analysis makes it possible to draw the distinction between local recurrence and a second local tumor localization, and pulmonary metastases from a second pulmonary localization. Finally, the prevention of rare lymphnode recurrences is considered in terms of specific surgery for this purpose.

Chronic Disease↗
PubMed1977

[Follow-up surgery for carcinoma of the tonsil (author's transl)].

This study involves the frequency, techniques and results of follow-up surgery for carcinoma of the tonsil treated by transcutaneous radiotherapy. Local or lymph node failures affect 65% of patients treated by radiation. Follow-up surgery was used in 86% of these failures. After reviewing the various techniques and their oncological results, the authors discuss the best timing for follow-up surgery. They compar their results of surgery in the case of sub-total treatment, surgery for recurrences and routine surgery two months after the end of transcutaneous irradiation. The results are in favour of routine surgery. If it is accepted, since this point is open to discussion, that radiotherapy remains the appropriate initial, and sometimes adequate, treatment for carcinoma of the tonsil, the frequency of local and lymph node recurrences should lead to the indication, in certain cases, for complementary surgical therapy. This routine additional surgical treatment should be discussed in the context of the initial protocol of the treatment of a carcinoma of the tonsil.

Electrocoagulation↗
PubMed1975

[Cutaneous elastopathy and vascular anomalies associated with neurological disorders. Apropos of 2 cases].

The two cases described exhibited elastopathy associated with arterial stenosis (case 1) or aneurysms (case 2). The first was clearly a case of elastic pseudo-xanthoma with characteristic cutaneous lesions associated with retinal angioid streaks and severe arterial lesions, notably stenosis of the vertebral arteries (especially the left) causing disorders in the mechanism of balance. There were, in addition, mild diabetes, hyperlipidaemia and abnormal cutaneous pigmentation. The second patient, an African, had been hospitalised for an optochiasmatic syndrome which further investigation, notably by arteriography, indicated was caused by compression of the visual pathways due to massive bilateral carotid aneurysms. The patient had molluscoid pseudo-tumours of the axillae and she reported that her father was in the same condition. Although in the first case, cutaneous biopsy enabled diagnosis of systematized elastorrhexis to be confirmed, histological investigation in the second case revealed mainly hyaline sclerosis of the deep dermal layer. The diagnosis of Ehlers-Danlos disease, suggested for this second patient, could not be confirmed. These two cases emphasize the possibility of various neurological disorders occurring in the course of dystrophy of the connectivo elastic tissue.

Adult↗
PubMed1975

[Comparison of long-term carcinologic results between radical and conservative cervical surgery].

The aim of this research was to compare isolated ganglionic development in patients treated surgically for cancer of the larynx. This research included the cases of 232 patients operated on for laryngeal cancer and who underwent either total laryngectomy with or without conservation of the cricoid, or supra-glottal laryngectomy, or sub-glottal pharyngectomy. For the treatment of the ganglionic areas, there are six possibilities: --cobalt used in isolation; --uni- or bi-lateral cellulo-adenectomy; --uni- or bi-lateral curettage (a month apart); --curettage on one side, cellulo-adenectomy on the other. The results obtained were particularly significant as far as the N0 and regrouped N1 were concerned. The rate of ganglionic recurrence was 25 p. 100 for the N0 treated with cobalt and 6,5 p. 100 when surgery was carried out (cellulo-adenectomy or curettage). Also, curettage seems in N + cases to give better results : 26 p. 100 recurrence in cases of cellulo-adenectomy for N0-N1 and 4 p. 100 only in cases of curettage. These results appear to justify on the spot histological examination followed by curettage in N + cases.

Cobalt Radioisotopes↗
PubMed1975

[Re-establishment of tracheal continuity by lowering the larynx after tracheal resection].

The authors describe a technique for re-establishing tracheal continuity after anastomotic resection of the cervical and cervico-thoracic trachea. Simply lowering the larynx cervically without an associated thoracic phase enables termino-terminal anastomosis of the trachea to be carried out after resection of more than 5 cm. In this article, the technique and the results obtained in 8 cases of pure tracheal stenosis are described in detail.

Anesthesia, Intravenous↗