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Biomedical subjects

H L Chan

Publications and source records attributed to H L Chan.

161 records · Page 9Linked to original sources

Panniculitis (Rothmann-Makai), with good response to tetracycline.

A case of idiopathic cirucumscribed panniculitis of the legs, with features consistent with that of the Rothmann-Makai syndrome, is reported. The response to a 10-week course of oral tetracycline therapy was impressive. It is suggested that the anti-lipase activity of tetracycline could account for this response.

Administration, Oral↗

Lupus-scleroderma syndrome induced by ethosuximide.

Features of both systemic lupus erythematosus and scleroderma developed in a young Chinese girl while on multiple anticonvulsant therapy. These were reversed after withdrawal of the drugs. Readministration of ethosuximide for control of epilepsy caused a relapse with predominant sclerodermatous features. These clinical signs again resolved after ethosuximide withdrawal.

Adolescent↗

Continuous and online analysis of heart rate variability.

Spectral analysis of heart rate variability provides a probe to assess the function of the sympathetic and parasympathetic nervous systems. Time-frequency analysis of heart rate variability is useful for investigating autonomic nervous function in patients with syncope or non-sustained ventricular tachycardia, or in anaesthesia, etc. In this paper, we developed an algorithm for continuous and online analysis of heart rate variability. The algorithm was simulated and evaluated in MATLAB, and implemented on the digital signal processor. The electrocardiogram signals from MIT/BIH arrhythmia database and one patient with syncope demonstrate the capability of the proposed method in the continuous and online analysis of heart rate variability.

Algorithms↗