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H Kucera

Publications and source records attributed to H Kucera.

At least 109 records · Page 6Linked to original sources
PubMed1980

[Histomorphologic examinations of bone marrow of patients with gynecologic malignoma before, during, and after radiotherapy (author's transl)].

The histomorphological changes in the bone marrow were investigated in 9 patients treated by primary irradiation for cervical cancer. Bone marrow specimens were obtained by the Yamshidi puncture technique from the spina iliaca posterior superior after radiotherapy with different radiation dosages, as well as four months after termination of radiotherapy. All patients showed disappearance of almost all the haematopoietic cells in the irradiated area and, with the exception of one patient, no repopularization of the bone marrow or fibrosis. The possible mechanisms leading to these results are discussed and comparisons with the international literature are drawn.

Aged↗
PubMed1980

[The treatment of inoperable endometrial cancer by means of intracavitary radiotherapy (author's transl)].

Epidemiological data are presented to point out the importance of endometrial cancer and the role of primary irradiation. 650 patients with endometrial cancer, who could not be operated because of local tumor spread or contraindication to surgery were treated by primary irradiation at the Department of Radiotherapy of the 1st University-Clinic of Gynecology and Obstetrics in Vienna. 312 patients (48%) were alive after five years. Severe proctitis and/or cystitis was seen in 10,8% fistulas in 2% of the treated patients. These results were obtained with conventional intracavitary radium application.

Adolescent↗
PubMed1980

[The importance, results and complications of intracavitary radiotherapy of inoperable cervical carcinoma. (report about 1586 cases) (author's transl)].

In the Department of Radiotherapy of the 1st University-Clinic of Gynecology and Obstetrics in Vienna (between 1962-1972) 1586 patients have been irradiated primarily due to carcinoma colli uteri. The National Cancer Registry in Austria shows, that 31% of new cases are aged 60 years and over. In the Annual Report of the results of treatment in carcinoma of the uterus, vagina and ovary (Vol. 16) the statistic of German-speaking countries shows, that 36,5% of cases of carcinoma colli uteri are in the inoperable stages. 757 of the 1586 patients (47,7%) survived five years and longer. The permanent reactions like recto-vaginal-fistula and vesico-vaginal-fistula were only seen in 3,2%. These results were obtained primarily by simple intracavitary radiotherapy. No after-loading apparatus and no high voltages percutaneous therapy were available during the study period.

Adult↗
PubMed1980

[Irradiation therapy of recurrent cervical carcinoma (author's transl)].

A report is presented of 141 irradiated cases of recurrent cervical carcinoma, 48 (34%) of the patients have survived for more than 2 years and 21 (15%) have survived yet more than 5 years. It is noticed, that the survival-rate is neither dependent on the localisation of recurrence, nor the beginning date nor the method of radiation therapy. It is pointed out, that the re-irradiation of primarily irradiated patients give also good results.

Female↗
PubMed1980

[Radiation therapy of cervix cancer with special reference to radiation effects upon the intestine (author's transl)].

The evaluation of the therapeutical preference of succession in the treatment of the uterine cervix, the radiation therapy today presents a special importance. This is established upon two facts; that is, the age-distribution and the incidence of the inoperability of the cases (one patient in every three cases of the cervical cancer is over 60 years of age; nearly 60% of the cases are in an inoperable stage). Although in our department only partially or completely inoperable cases went through a radiation therapy, 757 ( = 47,7% out of 1586 cases) achieved to survive for more than five years. At a discussion concerning the intestinal complications which occur due to irradiation, it has been proved, that 18,6% show reversible reactions. The permanent reactions like recto-vaginal-fistula etc. were only seen in 2,4%. It is interesting to note, that the patients subjected to intestinal complications were seen by advanced cases (stage III: 65,1%) and 69% of them were over 60 years of age. Irradiation consequences are by younger patients and by cases with a possible local operability rather rare. At the end, physiopathology and the treatment of the intestinal post-irradiation effects are discussed.

Age Factors↗
PubMed1980

[Biorhythm theory and primary irradiation of inoperable cancer of the cervix (author's transl)].

Hundred patients with inoperable cancer of the cervix, who had been treated by primary irradiation, were reviewed with regard to biorhythm on the days of radium application. 5-year survival was lower in patients with unfavorable biorhythm; the differences, however, were not significant. It is concluded that the calculation of biorhythm for the day of radiotherapy has little or no influence on the results of therapy.

Carcinoma, Squamous Cell↗
PubMed1980

[Adjuvanticity of vitamin A in advanced irradiated cervical cancer (author's transl)].

For treatment of patients with inoperable cervical cancer (FIGO III) a randomized trial has been initiated. Patients were randomized to receive either conventional irradiation therapy together with vitamin A palmitate (1.5 mill. IU/day; total dose 30 mill. IU), applied orally, or irradiation alone. 42 patients have been included in this study. Patients were monitored by several immunological tests. Delayed cutaneous hypersensitivity reaction to a battery of recall antigens did not reveal any changes, neither within nor between the treatment groups. A challenge reaction to DNCB could be evoked after treatment in 50% of the patients in both treatment groups. No significant changes of immunoglobulin levels have been observed after termination of therapy in each treatment group. When lymphocyte reactivity to PHA (maximum response during therapy) was compared within the groups, it was found, that 66% of the patients who received an irradiation combined with vitamin A palmitate, showed an increase in their blastogenic response, while in irradiated patients without vitamin A palmitate a response was only in 33%. This difference being statistically significant in comparison to pretreatment values. From immunological data it can be concluded that vitamin A has an effect on functional response of T-cells. Concerning the clinical outcome, after an observation period of 12 months relapse rates were lower in the vitamin A group, but not significantly reduced. Therefore further follow up is warranted.

Carcinoembryonic Antigen↗
PubMed1980

[Results of operation and irradiation in 683 cases with ovarian carcinoma (author's transl)].

A report is given on 683 cases of ovarian cancer, who underwent postoperative radiation therapy at the Radiation Department of the 1st University-Clinic of Obstetrics and Gynecology in Vienna. An uniform staging and histological classification is complicated by the fact, that in recent years the rate of cases operated elsewhere and subsequently admitted to our clinic went up to 76%. Of all 683 cases, 193 (28,3%) reached a five-year survival time. Because of these still unsatisfying results of postoperative radiation treatment in ovarian cancer the importance and necessity of randomised studies with different therapeutic programs is emphasized.

Adult↗
PubMed1980

[Electromedical methods for pain reduction during delivery (author's transl)].

The authors of this paper interviewed 200 pregnant women and another 200 patients on their own maternity ward to find out about their views and wishes regarding pain reducing procedures during delivery, with or without reduced consciousness in the course of labour. Only 13 per cent of them wanted to sleep during delivery, while almost 90 per cent insisted on being kept fully alert and on playing an active role in childbirth.--Yet, there has been growing demand for analgetic treatment among maternity ward patients, which, obviously, has been attributable to birth trauma. For example, the percentage of women who asked for peridural anaesthesia grew from 36 ante-partum to 64 post-partum.--The replies given by the patients then were related by the authors to the results of transcutaneous nerve stimulation (TNS) and cerebral electric stimulation (CES). Both methods had good effects on more than 50 per cent of the cases and partial effects on 25 to 30 per cent.--The authors feel that those no-risk simple methods should give good results in most cases in terms of less labour pain with full consciousness. Other methods, with higher risk, might be reserved for patients on whom simple methods fail.

Cerebral Cortex↗
PubMed1980

[Treatment of the carcinoma of the vulva at the 1st University-Clinic of Gynecology in Vienna (386 cases) (author's transl)].

In the department of radiotherapy of the 1st University-Clinic of Gynecology and Obstetrics in Vienna the electroresection and electrocoagulation is practiced with good success in the treatment of carcinoma of the vulva. Of 386 treated cases with vulvar carcinoma, 234 (60,6%) were alive after five years. After surgical treatment the inguinal lymphonodes were irradiated (6000 rad). In comparison with the international statistic of the Annual Report of the results of treatment in gynecological cancer (1979) the results obtained in Vienna are much better than the international average.

Aged↗
PubMed1979

[Epidemiology of breast cancer in Austria (author's transl)].

In cooperation with the Austrian National Institute for Statistics the incidence-rates of breast cancer in Austria in the period of 1971-1975 were investigated. The incidence-rate of breast cancer (50 new cases/year/100,000 women) is higher than the incidence-rate of cervical or endometrium carcinoma. The increasing risk of the higher age-groups, which is especially expressed by the incidence-rate of 145 in the age-group of 70 or more years, is pointed out. This findings are of great consequence to the system of preventive medical care. In urban areas the incidence of breast cancer seems to be higher than in rural district.

Adolescent↗
PubMed1979

[Perinatal mortality in twin pregnancies. Progress in perinatology].

162 twin pregnancies of the I. Univ.-Clinic of Gynecology and Obstetrics in Vienna between 1969 and 1977 have been analysed (1969--1974 = group I; 1975--1977 = group II). It was found that the main risk factors of twin gravidity are the high rate of babies born before term, the high rate of operative deliveries and the high rate of perinatal mortality. The twin pregnancy should be diagnozed early. This allows the possibility of prophylactic therapy of onset of labour before term. According to our observations the difference in mortality rates between the first and the second group is very high (13,3 in comparison to 5,5%). The management of twin pregnancies as a high risk delivery with continuous fetal monitoring has doubled the number of indications for caesarean section. The essential problem of twin pregnancy seems to be the high rate of premature deliveries. Therefore an adequate increase of the legal antenatal and postnatal maternal protection period is emphasized.

Birth Weight↗
PubMed1979

[Perinatal problems in breech presentation].

543 cases of breech presentation at the 1st Clinic of Obstetrics and Gynecology of the University of Vienna were investigated. The rate of Cesarean section showed during the last years a distinct increase (1969 to 1973: 16,6%, 1974 to 1977: 27,9%, 1977: 39,7%). A significant decrease of perinatal mortality in cases of breech presentation was not observed. On the other hand an increase in Cesarean sections diminishes the rate of perinatal mortality. In this publication the findings concerning the obstetrical results using abdominal or vaginal delivery are compared. No significant difference in perinatal mortality could be found. A better result could only be achieved in cases of mature infants. Our point of view is, that at present the indication of Cesarean section for cases of breech presentation should be very liberal. On the other hand vaginal delivery in some cases is still of importance.

Abnormalities, Multiple↗
PubMed1979

[The necessity of preventive gynecological studies in the aged].

According to epidemiological data the majority of the old women suffers from mammary cancer or gynecological malignoma. In cervical uterine cancers this ratio reaches more than 30% and in uterine body, ovarial and breast cancers more than 60%. Thus, it is significantly clear, that gynecological preventive medical examinations are so important. For cervical cancer cytology and for breast cancer mammography and thermography are valuable and satisfactory methods. Because of the lack of a practicable preventive examination method for corpus cancer and ovarial carcinoma it is evident, that regular clinical investigations are of vital importance in this field. Vulva and vaginal cancers are to be mentioned as real old women's neoplastic disease, because it starts mostly between 7th and 9th decade of life.

Aged↗