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Biomedical subjects

H Kraus

Publications and source records attributed to H Kraus.

At least 91 records · Page 5Linked to original sources
PubMed1981

[Cytological differential diagnostic accuracy in severe dysplasia and carcinoma in situ of the cervix and possible clinical consequences (author's transl)].

Since 1943 when Papanicolaou introduced cytology into gynecology the method has changed from a simple screening test into a sophisticated morphologic technique, the differential cytology. In Germany this development is documented by an improved cytologic classification (Münchner Nomenklatur). An own material is presented consisting of 520 cases of histologically proven severe dysplasias and in situ carcinomas. It can be shown that careful and critical use of differential cytology with due regard to its limits can improve the accuracy of the cytologic prediction of a cervical lesion. A delineation against invasive cancer is possible with a hundred percent accuracy. On the basis of these results it seems justifiable to perform a primary hysterectomy without pretherapeutic cone-biopsy. It is pointed out that this procedure is only possible in institutions were the possibilities of differential cytology are well-known and--which is more important--where the limits of the method are known and respected. In any case of doubt the procedure of diagnosis and therapy has to be discussed and planned in close cooperation between the clinicians and the morphologists.

Carcinoma in Situ↗
PubMed1981

[Cytologic studies after insertion of intrauterine contraceptive devices (IUD) (author's transl)].

Cervical smears of 554 women using IUDs were examined. The following criteria were evaluated: 1. Age distribution, 2. maturation index of the vaginal epithelium, 3. vaginal flora, 4. cytologic criteria of inflammation, 5. period of time between insertion of the IUD and the cytological examination, 6. final cytologic diagnosis. 554 women without IUD and normal gynaecological status served as a control group. It was the goal of the study to find out, firstly if IUDs in situ produce typical and specific changes in the cytologic pattern and secondly if the rate of suspicious and positive findings is increased: In IUD using women the rate of cases with unphysiologic vaginal flora is increased, the rate of inflammatory cytologic specimen is also higher than in the control group. The rate of inflammatory smears decreases with the increasing interval of time between insertion and cytological examination. IUD typical changes could be observed only in so far as in this group the cytologic signs of chronic cervicitis were increased. Inflammatory alterations are the reason for the higher rate of "suspicious" smears in the group of IUD-users. There was no higher rate of praecancerous lesions among the IUD users. The importance of these results for the clinical management are pointed out.

Adult↗
PubMed1979

[Follow-up and management of patients with incomplete cone biopsies for dysplasias (author's transl)].

Report of 86 cone biopsies for dysplasias of the cervix. In 11 of these cases the cone biopsy did not show a clearly dysplasia free margin. These patients were followed from 1 to 6 years without further treatment and none showed a suspicious or positive pap smear. In young patients who desire further pregnancies it appears to be justified to follow without further treatment even after incomplete cone biopsies for dysplasia. Two patients with complete removal of the dysplasia and a normal margin in the cone biopsy later showed positive pap smears. The importance of further follow-up of the cases is stressed.

Aftercare↗