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Biomedical subjects

H Koller

Publications and source records attributed to H Koller.

At least 37 records · Page 2Linked to original sources

[Contaminating substances in 22 over-the-counter fish oil and cod liver oil preparations: cholesterol, heavy metals and vitamin A].

Fish oil capsules are increasingly used by self-medicating patients. We studied 22 commercial fish oil and menhaden oil preparations in respect to accompanying substances that could be harmful. The substances measured were: cholesterol as determined by gas liquid chromatography, heavy metals measured by atomic absorption, and vitamin A as determined by high-performance liquid chromatography (HPLC). The contents of cholesterol and heavy metals were in ranges which can be regarded as negligible; the content of vitamin A in menhaden oils, however, was found in amounts which warrant that pregnant women do not exceed the dosage as recommended by the manufacturers.

Animals↗

[Angina pectoris].

Coronary heart disease has many different clinical courses: it can cause rhythm-disturbances, sudden death, pump-failure, no pain at all (silent ischemia) or typical angina. Heart-pain can occur "on demand" after physical or mental stress with a duration of 3 to 5 minutes with typical location and good response to nitrates. It also can cause atypical forms of angina such as angina on rest, mostly due to coronary spasms. Angina can stable over months and years but can suddenly increase in severity and duration. This form is called unstable angina, which has to be recognized as soon as possible since acute myocardial infarctions evolve rather frequently. Infarction is an irreversible myocardial damage but before it develops many measures can be taken to preserve the jeopardized myocardium. The recognition and differentiation of angina pectoris is therefore of utmost importance.

Angina Pectoris↗

Marriage in a young adult mentally retarded population.

Marriage was examined in a total population of mentally retarded young adults born in a 5-year period. No one with severe retardation had married. Among the mildly retarded, significantly fewer young people had married by age 22 than in a nonretarded comparison population, and the retarded young people who had married had significantly higher IQs than the remainder of the mildly retarded population. The retarded females had significantly more problems in their marriages than nonretarded comparisons. Nevertheless, the marriages of almost half the mildly retarded young women appeared to be working out well. The retarded young men were not significantly different from nonretarded comparisons. Marriages in which both partners were retarded had many problems.

Adult↗

Peer relationships of mildly retarded young adults living in the community.

Socializing with peers and opposite-sex relationships were examined in two subsets of a mildly mentally retarded (MMR) young adult population living in the community: those who were no longer receiving MR services and those who were attending day centres for MR adults. The MMR young people not receiving services had fewer best friends and socialized significantly less often than a nonretarded comparison population. The MMR males not receiving services also had fewer opposite-sex relationships than comparisons but this difference was not significant for the females. At age 22, these MMR young people continued to see friends from school significantly less often than comparisons, indicating a possible detrimental effect of special schooling on later socializing with peers. The MMR young people at the day centres socialized more often but this was done almost wholly with others who were MR. Within the MMR study population, the young women not receiving services socialized with peers the least, less than the young women at the day centres and less than the young men not receiving services, but they were married most often.

Adult↗

Job histories in open employment of a population of young adults with mental retardation: I.

Job histories were obtained for a population of young adults with mental retardation. No one with IQ less than 50 had been in open employment. Persons with mild mental retardation (n = 100) who received no adult services were compared to peers who were not retarded (n = 52) who left school without academic qualifications on a variety of job measures (e.g., unemployment, time out of the labor force, job turnover, level of job skill, and take-home pay). Among the 54 subjects with IQs of 50 or more who received adult services, approximately half had some open employment. Our results provide a less optimistic picture than that given by reviewers of previous research.

Adult↗

Sex differences in the classification of children as mildly mentally retarded.

A consistent finding in epidemiological studies of mild mental retardation (MMR) is a somewhat higher prevalence of boys than girls. Our own study in Aberdeen agreed with these findings. Examination of the numbers of boys and girls at different levels of retardation within our study population revealed the greatest excess at the highest IQ levels of greater than or equal to 75. This was found to be true in other studies as well. Since this IQ range is above the generally agreed upon cut-off point used to classify children as MMR, these findings suggest that boys remaining in regular classes may be having more difficulty in school performance than girls. Possible reasons for this are examined.

Adolescent↗

Antecedents of behavior disturbance in mildly mentally retarded young adults.

Behavior disturbance was found to be more frequent among mildly retarded (MMR) than a group of young adults matched during childhood for age, sex and social class. Reasons for this were examined. An unstable environment in childhood was found to be significantly related to behavior disturbance in both MMR and controls. The greater frequency of behavior disturbance among the MMR was due to their more frequently experiencing unstable environments in childhood than comparisons. Further, when stability of upbringing was held constant, differences in behaviour disturbance between the two groups were no longer found. Central nervous system damage was found not to be a contributory factor.

Adolescent↗

Factors leading to differences in the school performance of boys and girls.

Literature supporting the finding that boys do not fare as well in school performance during the first few years of school is reviewed, and possible reasons for this pattern are presented. These reasons are categorized as biological (e.g., X-linkage of intellectual traits) and social (e.g., sex-role training is more stringent for boys than for girls, and parents may place more pressure on boys for academic achievement). Social factors are presented in light of the rapid social change that has been taking place in the carrying out of adult sex roles and whether this has filtered down to changes in the sex-role training in the socialization of children. Pediatricians should be aware of whether school problems are occurring for both boys and girls, and their responses to such problems may differ, depending on the child's sex.

Achievement↗

A longitudinal study of numbers of males and females in mental retardation services by age, IQ and placement.

A year-by-year analysis up to age 22 was carried out of the numbers of males and females in a birth cohort receiving mental retardation services in a British city. A slight excess of males was found during childhood, with the largest excess occurring at the upper end of the IQ range, the borderline area for classifying children as mentally retarded. There was also a large male excess found in residential care at each age. During the young adult years, this predominance of males in residential care was offset by an excess of females attending day care centres, leading to almost equality of numbers of males and females receiving some sort of services during this period. Possible explanations for the findings were discussed.

Adolescent↗

Sex differences in number of children administratively classified as mildly mentally retarded: an epidemiological review.

Many epidemiological studies of mental retardation have shown a higher prevalence of boys than girls. Data were reviewed from various studies consistently showing that the highest male/female ratios are found at the upper end of the IQ range for children classified as mentally retarded. One reason for this may be that boys with IQs at the upper end of this range have greater difficulty than girls in meeting the requirements of school performance. Factors that may cause boys to experience more difficulties than girls in the early school years were reviewed.

Child Development↗

Appearance and mental retardation: some first steps in the development and application of a measure.

A measure of atypical appearance derived from components developed during the course of a study of 22-year-old mentally retarded adults was described. Hypotheses about relationships between mental retardation, biological damage, and appearance were tested and confirmed. Atypical appearance increased with severity of retardation. Mildly retarded young adults who received no mental retardation services after age 16 were more atypical in appearance than were nonretarded peers. Issues relating to the appearance measure and the results were discussed.

Adolescent↗

Relationship of upbringing to later behavior disturbance of mildly mentally retarded young people.

Factors were examined that might explain the higher rate of behavior disturbance found in a population of mildly mentally retarded young adults compared with nonretarded peers. Results showed that neurological impairment, found in one-third of the retarded subjects, was not a factor. Three results supported the explanation that instability of upbringing was responsible for the difference in behavior disturbance: a significant relationship was found between upbringing and behavior disturbance for both retarded and nonretarded subjects; conditions of upbringing were significantly more unstable among the retarded than nonretarded subjects; and when upbringing was held constant for both sets of subjects, no differences were found in behavior disturbance.

Adult↗

Career paths through mental retardation services: an epidemiological perspective.

Children born during a five year period, resident in a British city, and administratively defined as mentally retarded were followed up at age 22. Age specific prevalence rates ranged from 2.5/1000 at age 5 to 14.7/1000 at age 11. The various mental retardation services for children and adults are described and the frequencies with which different paths through services were followed are given. Almost three-quarters of those who had been at a school for educable, mentally retarded children received no services in the young adult period. The distributions of various associated disabilities among those receiving different services after leaving school are given. These illustrate the multiple problems presented by those who continue to require services in adulthood. The epidemiologic data presented provide a basis for estimating service needs.

Adolescent↗

The prevalence of mild mental retardation in the adult years.

Most mildly retarded children do not receive mental retardation services after leaving school. Those who do, however, represent a sizable proportion of adults receiving services. Nevertheless, their needs may be overlooked, since most adult programmes are designed to serve more severely retarded individuals. In this paper prevalence rates for mild mental retardation in the early adult years are given for one community, and the ways in which rates vary using different definitional criteria are demonstrated. Problems related to estimating the adult service needs of mildly retarded individuals are examined in relation to suggestions offered by Baroff (1982).

Adolescent↗

Behavior disturbance since childhood among a 5-year birth cohort of all mentally retarded young adults in a city.

A behavior disturbance classification was described and its distribution in childhood and the postschool period examined in a 5-year bith cohort of mentally retarded young adults. Approximately 60 percent had some behavior disturbance in each period. Hyperactive behavior was most frequent among children with lower IQs and antisocial behavior among children and young adults with higher IQs. Aggressive conduct disorder in childhood was most frequent among those with IQs below 50. Emotional disturbance was more frequent among females in the postschool period, and antisocial behavior was more frequent among males, both in childhood and the later period.

Adolescent↗