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Biomedical subjects

H Koch

Publications and source records attributed to H Koch.

At least 289 records · Page 16Linked to original sources

[Microangiographic examinations of different human tumors after transplantation to thymus aplastic nude mice].

Ten different human tumors (two soft tissue sarcomas, seven adenocarcinomas of the colon and stomach and, one squamous cell carcinoma of the lung) were implanted s.c. in thymus-aplastic mice and retransplanted over several generations. In 40 animals, the tumors were studied by microangiography and microscopy and classified according to angiographic tumor criteria. Tumor transplants always revealed similar angiographic patterns. The microscopic results presented a good correlation with the roentgenologic findings. The microstructure of the tumor vessels and lacunes are analyzed and discussed. The nude mice model is well suitable for the research of human tumors.

Angiography↗

Polypectomy in the presence of portal hypertension--an increased risk of bleeding?

A report is presented on 58 polypectomies performed in the stomach and colorectum in 46 patients. Twenty-five patients had portal hypertension consequent on liver cirrhosis, while 21 patients had healthy livers. The question as to whether haemorrhage occurred immediately after polypectomy or within the next 24 hours, was investigated. Furthermore, either the stalk (of pedunculated polyps), or the polyp itself (when sessile) was investigated pathologically-anatomically, with respect to its vascularity pattern. The submucosal and intramucosal vascularity patterns were classified in 4 categories, I to IV. A tentative interpretation of the results obtained indicates, on the basis of their mucosal and submucosal vascularity patterns, that patients with portal hypertension developing from a cirrhosis of the liver, are not at any higher risk of haemorrhage than patients with no portal hypertension.

Adult↗

[Clinical value of endoscopic papillotomy].

Endoscopic papillotomy (EPT), which has been developed from retrograde cholangiopancreaticography (ERCP) is without any doubt the most spectacular procedure among the various methods of operative endoscopy. Worldwide experience shows that with the necessary know-how, which is an essential condition, it is a highly successful procedure with encouraging results. EPT is, however, still the method in operative endoscopy with the highest complication rate. Therefore it should only be performed by strictly taking into account the indications. Moreover it should be a prerequisite that an experienced surgeon is at hand who can intervene immediately when complications occur.

Acute Disease↗