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Biomedical subjects

H Klosterhalfen

Publications and source records attributed to H Klosterhalfen.

At least 55 records · Page 3Linked to original sources

[Do biopsies and operations lead to formation of distant metastases? (author's transl)].

In medical and public literature the radiologist Krokowski states that diagnostic and operative procedures of cancer disease often stimulates the development of metastases. He believes that 30--90% of metastatic disease is the result of prior operations. Consequently he requires a prophylactic radiation therapy before any operative therapy is done. The authors question the theses of Krokowski since there is no detail presentation of this methods, which therefore cannot be repeated.

Biopsy↗

[Treatment of prostatic carcinoma stage C with combined perineal and transurethral cryosurgery (author's transl)].

31 patients with prostatic carcinoma stage C were treated by combined perineal and transurethral cryosurgery. Additionally in all patients a subcapsular orchiectomy was performed. A distinct tumour reduction was found in all patients. Six months after the freezing a palpable tumour could be detected only in 4 cases out of 29. At different time intervalls after the operation 57 biopsies of the prostate were obtained with the tru-cut-needle. In 14 patients no tumour tissue could be detected whereas tumour cells were found in the biopsies of the remaining patients. Combined perineal and transurethral cryosurgery therefore is a palliative form of treatment in prostatic carcinoma.

Aged↗

[Pathogenesis and therapy of varicocele (author's transl)].

During the last 13 years 519 patients were operated upon for varicocele in the refertilisation center Hamburg. Out of 209 cases examined thereafter, 174 showed an improved spermiogram, and only in this group 40 children were fathered. Pathogenesis, diagnosis and surgical treatment are presented. A persisting varicocele (in our clientele in 1 per cent) was corrected in 18 patients. The reasons for recurrent surgery were overlooked branches of the V. spermatica interna and not yet described collaterals to neighbouring venous systems. For optimal surgical planning the latter are best demonstrated by preoperative phlebography.

Adolescent↗

[Open prostatic surgery in patients over 80 years (author's transl)].

The fact that a patient needing prostatic surgery is over 80 years old need no longer be a reason why open surgery should not be considered in the treatment programme of the general practitioner or internal physician. Out of 45 men aged between 80 and 92 only two died as a result of surgery. Life expectancy is not reduced by the operation.

Age Factors↗

[A new substance for the therapeutic embolisation of renal tumours (author's transl)].

We report on a radio opaque substance for the embolization of kidney tumours which consists of amino acids mixed up with a contrast medium. It is relatively easy to be injected and can be well directed because of its radio-opacity. Past and recent histological examinations of embolized pig kidneys show that this material provides a durable closure of the vessels and that there is no essential tendency of intravasal dissolution. It is therefore also suitable for palliative embolizations. The first results in clinical trial have proved to be encouraging.

Amino Acids↗

[Occult reflux (author's transl)].

Level diagnosis repeatedly performed in patients without roentgenologically demonstrable reflux demonstrated bladder bacteriuria in 80% of the cases. The remaining 20% had supravesical bacteriuria. We called this occult reflux, if reinfection was demonstrated. Contamination of the upper tract by occult reflux can, but must not induce pyelonephritis. Bilateral antireflux surgery frequently eliminates occult reflux of bacteria, so this seems a debatable method of treatment.

Adolescent↗

[The bilateral nephrectomy in terminal renal disease (author's transl)].

45 cases of nephrectomy are reported. Mortality was 8.9%. Thirty-one had a drug-resistant, severe hypertension, three had infected kidneys, and in eleven cases nephrectomy was performed prior to transplantation. Although blood pressure improved in all patients, of the first group 24% died within one year after nephrectomy, which shows unsatisfactory prognosis of malignant nephrosclerosis. Only early nephrectomy can lead to better results. Routine nephrectomy before transplantation should be avoided. Indications for this group are discussed.

Adult↗

[Functional efficiency of the vesico-ureteral closure mechanism in female patients with recurrent urinary tract infections without reflux].

On account of different relapses of infections in 15 female patients with relapsing non-obstructive infections of the urinary tract without radiologically provable vesico-ureteral reflux altogether 183 washing out tests of the urinary bladder were performed. 83.6% of the tests resulted in a pure bacteriuria of the bladder and 14.2% in a supra-vesical participation. Of the 51 female patients 38 = 74,5% were always suffering only from bacteriurias of the bladder. In 13 patients = 25.5% we also or always found a supravesical participation. 15 female patients underwent a reflux test with technetium-levelled sulphocolloid. In no patient the tracer could be localised in the supravesical urinary tract. By reason of these results we are of the opinion that in the majority of female patients the vesico-ureteral occlusion mechanism does not allow an ascent of the germs. Therefore, the majority of patients is not imperilled by pyelonephritis. Among the female patients with relapsing non-obstructive infections of the urinary tract without radiologically provable reflux are some with marginally competent ostia. In these more or less frequently an occult reflux with ascent of the germs into the supravesical urinary tract may develop. These patients are potentially imperilled by pyelonephritis.

Adolescent↗

[Hemospermia].

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Genital Diseases, Male↗

Selective hypothermic perfusion of the kidney for intrarenal surgery.

Clinical experience and physiological consideration of selective hypothermia for conservative renal surgery are described. While surface cooling is satisfactory for relatively short ischaemia times, continuous renal perfusion via catheters offers the best wash-out and a completely bloodless field for lengthy surgical procedures. This is demonstrated by a comparison of three different methods of renal hypothermia in somewhat similar cases. During the last 6 years we have successfully used a continuous perfusion technique by direct introduction of catheters into the renal vessels in 16 selected cases. Advantages and drawbacks of this method are discussed.

Adult↗

[Kidney damage in sterile reflux].

On the basis of the data mentioned and taking into consideration the fact that the whole complex of problems is not yet clarified unequivocally we come to the following conclusions: 1. Up to now there are no proofs for the fact that the most frequent type of reflux, i.e. the simple reflux of the urine from the urinary bladder into the upper urinary passage causes a renal damage. 2. The complicated VUR may certainly cause a urinary stasis kidney. In simultaneous calyco-tubular reflux probably focal shrinkings of the parenchyma may develop.

Age Factors↗