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Biomedical subjects

H Kemona

Publications and source records attributed to H Kemona.

71 records · Page 4Linked to original sources
PubMed1980

Nitroblue tetrazolium test in the term small-for-dates newborn.

The value of the nitroblue tetrazolium reduction test was studied using granulocytes obtained from 41 small-for-dates and 23 normal term newborns. The unstimulated test did not show any differences between the two groups, while after latex stimulation a statistically significant decrease was noted in the reduction by granulocytes obtained from small-for-dates newborns in comparison to those obtained from normal newborn infants. The results showed a wide scattering especially in the small-for-dates newborns. This may indicate that in some of these babies the granulocytic enzymes are defective to reduce the nitroblue tetrazolium to purple formazan.

Blood Bactericidal Activity↗
PubMedDate not supplied

Serum concentration of alpha-2-macroglobulin, alpha-1-antitrypsin and alpha-1-antichymotrypsin [correction of alpha-2-antichymotrypsin] in patients with Hodgkin's disease.

In twenty four patients diagnosed with Hodgkin's disease we have determined several antiproteases. Our findings have shown the decrease of concentration of alpha-2-macroglobulin and increase of alpha-1-proteinase inhibitor and alpha-1-antichymotrypsin. The observed changes were statistically significant p < 0.001. We did not find any correlation between the concentration of inhibitors and the clinical stage of carcinoma and histopathological data. The determination of the level of antiproteases in patients with cancer disease may be assumed to reflect partly at least the capability of anticancer mechanism in the host.

Adult↗
PubMedDate not supplied

[Proteases and protease antagonists in neoplasms].

The maintenance of equilibrium between proteases and their inhibitors has substantial significance for the pathogenesis of the neoplastic disease. It concerns especially the invasiveness of the neoplasms, which increases with rising of the proteases activity or with the decrease of the inhibitory activity of antiproteases. The neoplastic cell has the faculty of producing numerous proteases which by damaging connective tissue facilitates the invasion by the neoplasm. Invasiveness of the neoplasms may be augmented by the production of proteases by the host cells stimulated by the neoplasm. The condition of the proteases--antiproteases balance is also influenced by the production of antiproteases by neoplastic cells. Among numerous antiproteases alpha-2-macroglobulin has most intensive cytotoxic action in relation with the neoplasm. According to data collected from the literature, antiproteases can be regarded as anticarcinogenic agents. On account of this, the estimation of the antiproteases level can be regarded as a measure of the ability of the body system to resist the invasiveness of neoplasms.

Connective Tissue↗
PubMedDate not supplied

[Phagocytic activity of platelets in patients with pneumonia].

In 22 patients with pneumonia the per cent of phagocytizing platelets and the phagocytosis index of the platelets were determined before treatment and in 14 patients this was done after treatment. Before treatment the per cent of phagocytizing platelets was 1.37%, on average, and after treatment it was 1.20, and it was thus much lower than in the control group X 2.33. The phagocytosis index before treatment was 1.39 on average, and after treatment it was 1.28, while in the control group it was 1.54. The obtained results seem to indicate that in pneumonia platelets participate in the antibacterial processes and the lungs as a thrombopoietic organ contribute to this phenomenon.

Adult↗