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Biomedical subjects

H K Deininger

Publications and source records attributed to H K Deininger.

At least 37 records · Page 2Linked to original sources

[Familial Osler's disease with lung involvement].

Hereditary hemorrhagic teleangiectasia is transmitted by an autosomal dominant character with typical vascular dysplasias in form of teleangiectasias and angiomas which occur on the skin, on the mucous membranes and also in nearly all organs of the body. More than 50% of patients with Osler's disease also have arteriovenous lung malformations. Therefore, pulmonary arteriovenous fistulas should be studied by x-rays for every member of a family suffering from this disease. To prove the suspicion of pulmonary arteriovenous fistula, the procedure of intravenous DSA should be used.

Adult↗

[Determination of the value of conventional and computer-assisted tomography in examining the thoracic organs].

We compared the results of CT and conventional tomography examinations of the thorax of 137 patients with each other and with the final results. In the diagnosis of bronchial carcinomas we found no significant differences between the two methods. In all other investigated items CT proved to be superior to conventional tomography, especially of the evaluation of mediastinum (90% vs. 35%). We conclude that CT is the method of choice in the staging of intrathoracic tumours and especially in the evaluation of hilar and mediastinal masses and there is no need for conventional tomography in these cases.

Carcinoma, Bronchogenic↗

[The value of the transbrachial approach for arterial visualization using a 4-F catheter].

To assess the safety of nonselective intraarterial digital subtraction angiography (DSA) performed from a transbrachial approach with 4-French-catheters, the complications occurring in 158 examinations were studied. Two patients developed local thrombosis and in four patients there were temporary pulse deficits. Three brachial artery catheterisations were unsuccessful due to transient arterial spasm. Our data support the conclusion that nonselective transbrachial DSA is a safe and accurate method, easily employed in an outpatient population.

Adult↗

[A primary pulmonary manifestation of Waldenström's macroglobulinemia].

A case of Waldenström's macroglobulinemia (MGW) is presented with a rare primary pulmonary manifestation. The disease was discovered from abnormal reticulonodular opacities in chest X-ray films, which at first did not have the classic features of MGW. The radiological findings and therapeutic possibilities are discussed with reference to the literature.

Female↗

[Spontaneous esophageal rupture--Boerhaave's syndrome. The clinical picture and diagnosis].

Spontaneous transmural rupture of the esophagus (Boerhaave's syndrome) is a life-threatening emergency. Prompt diagnosis is essential to a better prognosis, successful operative outcome and patient survival. The chest roentgenogram and the contrast esophagograms to follow are the most helpful diagnostic tests. The clinical manifestations are variable and may be misleading and thus delay accurate recognition. In our case report the major clinical features and radiological signs of Boerhaave's syndrome are described. The pathogenesis, characteristic clinical symptoms and the signs and radiological evaluation are reviewed.

Esophageal Diseases↗

[Traumatic atlanto-occipital dislocation in conventional x-ray diagnosis].

Different roentgenometric methods are discussed with reference to a case of atlanto-occipital dislocation (AOD). The most accurate information is provided by Lee's X-line method, which also allows differentiation of the three forms of this injury. As survival has been reported in cases of AOD, early conventional radiographic diagnosis is especially important.

Adult↗

[Computed tomographic diagnosis of an ileocolic invagination in an adult].

Intussusception is an uncommon cause of intestinal obstruction in adults. Unlike children, the diagnosis of intussusception in adults is often difficult due to its usually chronic history. A case of adult ileocolic intussusception secondary to metastatic melanoma is presented to discuss the efficiency of ultrasonography, characteristic CT features and the etiology of this disease.

Humans↗

[Mediastinal pancreas pseudocyst].

We report on the diagnosis and treatment of a pancreatic pseudocyst of the mediastinum. The patterns of signs and symptoms, diagnosis and treatment of this rare disease are discussed on the basis of literature.

Adult↗

[Significance of digital subtraction angiography in evaluating peripheral arteriovenous shunts in dialysis patients].

Direct and indirect examination of arteriovenous shunts was performed in 50 patients undergoing haemodialysis. The various methods of puncture of the vessels, the indications and the limitations of DSA are considered. The advantages of direct puncture of the arteriovenous shunt are emphasised. Puncture of the venous branch is almost without risk and allows immediate diagnosis. Only in a very few cases it will be necessary to perform the risky puncture of the arterial branch or the time-consuming central venous injection of a bolus of the contrast medium.

Adult↗

[Digital subtraction angiography and other non-invasive procedures for evaluating renal circulation and hypertension].

Nuclear medical techniques (such as isotope nephrograms, renal scintigrams) which are suitable as screening methods, have been unable to improve the diagnosis of reno-vascular hypertension. Amongst conventional procedures, the excretion urogram following a bolus injection was the most informative, particularly if performed together with nephro-tomography. Although ultrasound is of some use in evaluating the kidneys, the excretion urogram remains essential for the diagnosis of reno-vascular hypertension. Additional exposures and modifications (e.g. early phase urogram only add unnecessary radiation and cost without providing additional information. On the other hand, it would be useful to obtain digital subtraction angiograms of the renal arteries during the contrast injection. In this way, reliable information can be obtained on the cause of reno-vascular hypertension in more than 90% of patients. Similar results can be obtained by photographic subtraction (ISA). This should be used where DSA apparatus is not available. Angio-CT and sequential CT is not reliable for the diagnosis of renal artery stenosis. On the other hand, these methods provide density measurements or time-density curves of selected areas in the cortex or medulla of the kidney, which indicated abnormalities of the circulation and provide a comparison of the two sides.

Angiography↗

[Puncture biopsy of the lung. A retrospective evaluation of 127 observations].

On the grounds of a suspected localised tumorous lesion of the lung core biopsy (Tru-cut-needle) was performed in 127 patients to obtain a histologic diagnosis. This was successful on an average in 71.6% of the cases. The smaller lung lesions (less than 2.5 cm) showed a lower accuracy (65.2%) than the larger tumours (73.1%). Correct judgement of tumour status was effected in 88.2%. But in these cases also correct assessment of tumour status was less successful with the smaller tumours (69.6%) than with the larger ones (92.3%). In our case material core biopsy had a high complication rate: pneumothorax resulted in 54.3%, requiring special treatment in 9.4%. Haemoptisis was observed in 22.9% of which 2.4% had a severe and life-threatening clinical course. A correlation between these complications and the patient's age, the depth of the tumour in the lung and the frequency of the punctures was established. Pleural fluid was seen in 16.5% but in all cases it was negligible and no treatment was required. The pleural reaction showed no correlation to the age, to the tumorous lesion and to the frequency of puncture. The diagnostic advantage and the high accuracy of the core biopsy are evident. Nevertheless, we gave up this method in routine application in our lung tumour patients in favour of needle biopsy techniques. Core biopsy is still being used in examining special problems only.

Adult↗

[The solitary alveolar cell carcinoma].

Alveolar-cell carcinoma was first described by Malassez in 1876. It contributes 5 per cent to all malignant tumors of the lung. In a retrospective study 75 patients with alveolar-cell carcinoma were analyzed. Clinical symptoms are non-specific and the tumor will often be discovered on the occasion of a routine chest X-ray as a small peripheral and infiltrative lesion. The most frequent form is a nodule which generally shows a regular and well defined outline, but may sometimes be irregular and have spiky margins too. Very often an air bronchogram and the tail sign can be seen so the combination seems typical of solitary alveolar-cell carcinoma. In the case material investigated the authors found it in 36 per cent. The early stage of localized alveolar-cell carcinoma has a good prognosis when treated by surgery. Multilocular and advanced cases, however, have a very poor prognosis. Therefore, early radiological diagnosis is most important. The value of needle aspiration biopsy in the diagnosis of alveolar-cell carcinoma is emphasized.

Adenocarcinoma, Bronchiolo-Alveolar↗

Wegener granulomatosis of the breast.

Two cases of Wegener granulomatosis of the breast are reported. In both cases, this rare disease was detected on mammographic examination and was diagnosed for the first time by a fine-needle aspiration biopsy of the breast. The mammographic findings can lead to misinterpretations and can be confused with advanced mammary carcinoma or the alterations caused by lymphoblastoma, leukemia, or Hodgkin disease. The total regression of the tumorlike lesions in the breast, evidence of involvement of the lung with only slight clinical symptoms, and a very protracted course of the disease were remarkable in both cases.

Biopsy, Needle↗

Comparison of nephroangiotomography, intravenous subtraction angiography and digital subtraction angiography in the diagnosis of renal hypertension.

Nephroangiotomography (NATG), intravenous subtraction angiography (ISA) and digital subtraction angiography (DSA) were compared with regard to their specificity and diagnostic value, their expenditure of time, equipment and staff as well as to their risk for the patients. The interpretation of NATG is inferior to ISA. The hitting quota of ISA and DSA is equal. The expenditure of time and staff for ISA is important, whereas the equipment for DSA is considerable; however, it has a wider use. In case of a low patient number, ISA delivers sufficient results in the diagnosis of renal hypertension with the advantage that it can also be performed in smaller radiological institutes.

Humans↗