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Biomedical subjects

H Jonsson

Publications and source records attributed to H Jonsson.

113 records · Page 7Linked to original sources

Kinematics of active knee extension after tear of the anterior cruciate ligament.

Three-dimensional movements of the knees in 13 patients with unilateral old tears of ACLs were studied during extension. Roentgen stereophotogrammetric methods were used to measure tibial movements in the injured and the intact knees. Reduced internal rotation and adduction were recorded at the end of extension on both sides. The injured knees displayed increased anterior and distal displacements of the tibial intercondylar eminence. Abnormal tibial displacements in our patients indicate that the absence of the ACL is not completely compensated for during active extension past 30 degrees; close to the extended position, the tibial movements tend to normalize.

Adolescent↗

Evolving narratives in the course of retirement: a longitudinal study.

This paper presents results from the second phase of a longitudinal study of retirement. Data were gathered through interviews with 29 participants (65 to 66 years of age) who had previously been interviewed when they were 63 to 64 years of age and still working. Data were analyzed by characterizing each subject's narrative about retirement in terms of its narrative slope--progressive, stability, or regressive. These current narratives also were compared with the earlier narratives these participants told. It was found that, while anticipatory narratives may predispose persons toward action, they are not so much a fixed "script for action" as an orientation to act within circumstances. While participants' narratives anticipating retirement often turned out as expected, they were sometimes reshaped as a consequence of personal action, external events, and unexpected experiences within new retirement occupations. The study suggests that, while narratives play a role in shaping the direction of persons lives, they also interweave with and change directions as a result of ongoing life events and experiences.

Activities of Daily Living↗

Narratives and experience in an occupational transition: a longitudinal study of the retirement process.

This article presents the results from a longitudinal study of retirement. Data were collected through interviews with 12 Swedish participants over a 7-year period, beginning when they were still working and continuing through their early years of retirement. The findings show that the participants' narrative anticipations of retirement interacted with the events of ongoing life. Sometimes these events influenced the outcomes of the retirement process unpredictably. Consequently, retirement was often full of surprises and temporary periods of turbulence. Although some participants managed a transition into a satisfying pattern of retirement, others found it an ongoing process of frustration and dissatisfaction. Evidence from this longitudinal study indicates that a special type of occupation--engaging occupation with six constituents--was an important determinant of retirement satisfaction. This key finding is discussed with regard to its implications for theory development as well as its practical implications related to the importance of differentiating occupations and attending to the interaction between internal motivation and external expectations in the occupational pattern.

Aged↗

No effect of acetylcystein on refractory rheumatoid arthritis.

Acetylcystein has some chemical similarities with Penicillamine and other thiol containing compounds with effect on rheumatoid arthritis. We report an open trial on seven patients with refractory rheumatoid arthritis in which no beneficial effect could be seen after up to twelve months treatment in doses 600-1200 mg acetylcystein daily. No definite laboratory changes were seen, apart from a tendency towards higher IgA levels at the end of the treatment period.

Acetylcysteine↗

Prospective analysis of C1 dissociation and complement activation in patients with systemic lupus erythematosus.

OBJECTIVE: To evaluate the results of complement analysis for assessment of disease activity and severity, and prediction of flares in systemic lupus erythematosus (SLE). METHODS: Patients with mild extra-renal flares, severe extra-renal flares or flares of lupus glomerulonephritis were followed for eight months, with investigations being performed every second month. Findings in initial samples four months before the flares were compared with findings in a control group with stable disease. C-reactive protein, and circulating C1q, C4 and C3 were determined together with two types of complexes containing C1 inhibitor (C1 INH), C1 INH-C1r-C1s and C1 INH-C1r-C1s-C1 INH, and the C3 breakdown product C3d. RESULTS: Enhanced formation of C1 INH-C1r-C1s appeared to be a marker of low specificity and was mainly seen in patients with extra-renal disease. Concentrations of C1 INH-C1r-C1s-C1 INH, C3d, C1q and C3 clearly varied according to disease activity in patients with severe disease. Interestingly, high C1 INH-C1r-C1s-C1 INH values were found four months before the flares in all but one patient with lupus glomerulonephritis. Assessment of the relative predictivity for a subsequent flare indicated low C1q to be the most reliable marker, the predictivity of the complexes being: low C1q > high C1 INH-C1r-C1s-C1 INH > low C3 > high C3d > low C4. CONCLUSION: The importance of C1q and C1-related events in SLE may be underestimated. In addition, our results demonstrate the relevance of serial complement analysis for the assessment of disease activity and severity.

Adolescent↗