Search PubMed⌕ Search

Biomedical subjects

H Janisch

Publications and source records attributed to H Janisch.

At least 109 records · Page 6Linked to original sources

[Investigations concerning the evidence of herpes simplex virus type 2 (HSV-2) antibodies in patients with carcinoma of the cervix (author's transl)].

The neutralizing antibodies to HSV-1 and HSV-2 were determined in the sera of 128 patients. Infection was detectable in nearly 100% of the cases in each of the three investigated groups (patients with carcinoma of the cervix, female patients with chronic recurrent HSV infection in the genital area and a control group without and history of HSV infection). The percentage of patients displaying HSV-2 antibodies in the group with carcinoma of the cervix (38%) is significantly higher than in the control group (12%). The results are compared with the findings of other authors and the possible causal significance of HSV in carcinogenesis is discussed.

Adult↗

On radioactive labelling of the lymph drainage regions of the pelvis.

The introduction of radioisotopes in the surgical management of cervical carcinoma at our clinic in 1970 constituted a major advance in this respect. Prior to surgery the lymphatic tissue of the pelvic region is labelled by subcutaneous applications of radioisotopes. Our experience shows that the body's kinetics encourage the deposition of the radionucleide and thus visualization even of the groups of lymph nodes located in the deeper layers of the pelvic region. This method allows virtually complete lymphonodectomy with resultant improvement of cure rates.

Female↗

[Operative therapy of ovaria carcinoma (author's transl)].

125 women with ovarian carcinoma were surgically treated during the years 1968 to 1973. The 5-year survival rate was 39.1%. Operative management is the treatment of choice, whereby complete extirpation of the reproductive organy and the omentum should be attempted. Whilst there is no difference in the survival rate of stage I cases treated by the radical as compared with the partial operative procedure, a significant difference is seen in the remaining stages. A conservative operation should only be carried out provided the "healthy" ovary is simultaneously biopsied. In spite of the fact that the survival rate is dependent on other factors there can be no doubt that the pre-eminence of operation in the treatment of ovarian cancer.

Female↗

[Placental function and foetal lung maturity (author's transl)].

The placental function and foetal lung maturity were simultaneously assessed before delivery in 48 high-risk pregnancies, the actual time varying from case to case. A statistically significant correlation was found between placental function and foetal lung maturity. Since the actual time of investigation often lay back several weeks before delivery, no significant connection was detected between the state of foetal lung maturity at the time of amniocentesis and the clinical picture in respect to lung maturity of the infant at birth. The discrepancy is tabulated and possible causative factors are discussed.

Female↗

[Optimal monitoring in EPH gestosis and idiopathic placentar insufficiency (author's transl)].

EPH gestosis and placental insufficiency sui generis are cause of fetal hazards. Clinical symptomatology and anamnesis indicate different tests to detect pathological conditions for the fetus. HPL, HCG, urinary estriol, measuring the placental flow-rate, ultrasonic diagnosis as all other usual examinations during pregnancy were carried out. In EPH gestosis a reduction of all placental functions was found like as for thrombocytes and fibrinogen. Placental insufficiency showed an even greater reduction of placental function, only thrombocytes and fibrinogen remained constant. Weight and length of the newborn were according the pathological placental function reduced. Morphology of the placenta could proof the results of the previous done tests.

Adult↗

[Some considerations on forceps delivery with excenter handle (author's transl)].

The introduction of electronic monitoring techniques in delivery increasingly has lead to the use of vaginal surgery in delivery. Vacuum and forceps extraction, in our view, do not compete with each other. Years ago forceps extraction was decisively improved by introducing the axial traction forceps. However, we believe that this technique has not been given due attention and is not applied widely enough. In vacuum extraction and in forceps deliveries without axial traction considerable part of the force is exerted in the direction of the symphysis. When using the excentric handle forceps, it is necessary in addition to the traction and pressure components to include the lever action. This is a so-called couple of forces. The additional torque involved in the use of an axial traction forceps shifts the fetal head during extraction in the direction of the hollow of the sacrum. The force needed for this shift and the progression of the head is many times less than that required for conventional forceps extraction. This is due to the absence of the component directed at the symphysis which impedes delivery. The axial traction forceps may also be used in case of the infant's abnormal positioning of the head. In case of a transverse position of the fetal head, a special fastener on the forceps makes it possible to use an excentric handle on the traction hook of the Kielland forceps and thus render possible rotation of the fetal head from the transverse position. The extentric handle in forceps extraction is optimal in order to overcome increased mechanical resistance to delivery. Adjustment of the handles to all types of forceps being used today is possible. From the results mentioned it is clear that the use of the axial traction forceps constitutes a valuable contribution toward declining perinatal mortality rates.

Apgar Score↗