Biomedical subjects
H J Morowitz
Publications and source records attributed to H J Morowitz.
Jesus, Moses, Aristotle, and laboratory animals.
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The chemical logic of a minimum protocell.
Traditional schemes for the origin of cellular life on earth generally suppose that the chance assembly of polymer synthesis systems was the initial event, followed by incorporation into a membrane-enclosed volume to form the earliest cells. Here we discuss an alternative system consisting of replicating membrane vesicles, which we define as minimum protocells. These consist of vesicular bilayer membranes that self-assemble from relatively rare organic amphiphiles present in the prebiotic environment. If some of the amphiphiles are primitive pigment molecules asymmetrically oriented in the bilayer, light energy can be captured in the form of electrochemical ion gradients. This energy could then be used to convert relatively common precursor molecules into membrane amphiphiles, thereby providing an initial photosynthetic growth process, as well as an appropriate microenvironment for incorporation and evolution of polymer synthesis systems.
Vital records of Athol.
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Six hundred sixty-six minus sixty.
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Myasthenia gravis and arrows of fortune.
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Ecology and the great cold cereal rip-off.
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The mating poems of D. H. Lawrence.
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