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Biomedical subjects

H Huchzermeyer

Publications and source records attributed to H Huchzermeyer.

At least 73 records · Page 4Linked to original sources
PubMed1977

[The radiological diagnosis of non-calculous biliary duct obstruction (author's transl)].

A diagnosis of obstructive biliary duct disease was achieved in 80% of 63 patients using endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous trans-jugular cholangiography (PTJC) alone or in combination, and taking account of the clinical features. In obstructions of themajor intrahepatic ducts and of the hepatic ducts (type I) a smooth occlusion indicated a carcinoma. Narrow forms of stenoses could not be differentiated, but with a history of previous operation, fibrous strictures were most likely. Obstructions at the point of confluence (type II) showed smooth narrowing if due to fibrous strictures, whereas carcinomas produced an irregular termination. Obstructions of the common bile ducts (type III) resembled those of type II. A smooth termination within the pancreas indicates a pancreatic carcinoma. Inflammatory disease in the head of the pancreas usually produces a tubular stenosis, while cysts of the pancreas result in smooth impressions and displacement.

Bile Duct Neoplasms↗
PubMed1977

[Transjugular puncture of the portal vein. Portography and selective phlebography of abdominal organs. An experimental study in dogs (author's transl)].

Transjugular transhepatic portography is a new method for catheterising the portal vein and its tributaries. In order to gather experience of the method before applying it clinically, the transvenous approach was studied in six dogs. Transjugular portography has the following advantages as compared with umbilical vein catheterization and percutaneous, transhepatic portal vein catherterisation: 1. Because of the relative positions of the jugular veins, vena cava and portal vein, manipulation of the catheter for selective phlebography is simpler. 2. There is no risk of a haemoperitoneum or bile peritonitis if a correct technique is used since the liver capsule remains intact. 3. In the presence of portal hypertension, it may be possible in future to create an intrahepatic portocaval shunt by the transjugular approach without a major operation. Sclerosis of oesophageal varices is possible, as it is with the other procedures.

Animals↗
PubMed1977

Determination of splenic blood flow by inhalation of radioactive rare gases.

We have evaluated the 133Xenon inhalation method for the determination of splenic blood flow. In twenty-two healthy persons the blood flow was on average 109 +/- 4 mg/100 g X min, which is equivalent to a total blood flow of about 170 ml/min. In patients with chronic fatty liver hepatitis specific blood flow was reduced (81 +/- 10 ml/100 g X min) as it was in patients with cirrhotic liver without splenomegaly (75 +/- 2 ml/100 g X min). With increasing weight of the spleen, the total blood flow rises, although specific blood flow is low. Our results obtained by the 133Xenon inhalation method are similar to results obtained by others using intraarterial injection of tracer gas. The advantages of the inhalation method as a non-traumatic method are: (1) the stress for the patient is very small; (2) blood flow measurements can be repeated within short periods of time. We consider for the present the 133Xenon inhalation method to be the method of choice for the determination of the splenic blood flow.

Adult↗
PubMed1976

[The radiological findings in oesophagitis due to Crohn's disease (author's transl)].

The radiological changes in oesophagitis due to Crohn's disease are described in five patients. Like the pathological and anatomical findings, the appearances proved very variable. Neither in our own observations, nor in the literature, are there any radiological findings which are diagnostic. The diagnosis can only be made on the basis of radiological, endoscopic and histological findings.

Adult↗
PubMed1976

[Diagnostic procedures in congenital dilatation of the bile ducts (author's transl)].

A report is given of 29 cases with congenital dilatation of the bile ducts, and the value of different diagnostic procedures is discussed. Histology in combinations with clinical symptoms allows the diagnosis in cases with microhamartoma or with congenital fibrosis of the liver. Sonography is the most important procedure in the diagnosis of cysts of the liver (solitary cysts or polycystic conditions); it may be complemented by peritoneoscopy if diagnosis cannot be established with certainty by echogramm. If segmental dilatation of intrahepatic bile ducts (Caroli's disease) is suspected, intravenous cholangiography ought to be the first diagnostic step. A more reliable diagnostic procedure is endoscopic retrograde cholangiography (ERC) in theses cases; if ERC does not help, percutaneous transjugular cholangiography may be indicated. In establishing the diagnosis of cysts of the choledochus and of intra- plus extrahepatic dilatations of the bile duct systems sonography ought to be used in the first place; the method of choice in these latter conditions however is the ERC.

Bile Ducts, Intrahepatic↗
PubMed1976

[Antegrade visualization of the billiary duct system by percutaneous transjugular cholangiography (author's transl)].

Percutaneous transjugular cholangiography (PTJC) is a new technique for visualization of the biliary duct system and for diagnosis of obstructive jaundice. First experiences of the authors in 22 patients are described. The advantages and disadvantages of this procedure, which at the present time is used rather rarely, are discussed and compared to various other cholangiographic methods. The endoscopic retrograde cholangiography (ERC) was used for patients with obstructive jaundice of unknown origine in the first place. If the biliary duct system could not be visualized by ERC (failure of complete obstruction of the common bile duct), the antegrade technique (PTJC) was performed. The peritoneoscopic and the transjugular cholangiography yield about the same percentage of positive results (90%), as far as visualization of the biliary tree is concerned. However in contrast to the peritoneoscopic methods PTJC seems to bear a smaller risk of complications. Some further diagnostic and therapeutical advantages, which might result from the use of PTJC are pointed out.

Biliary Tract↗
PubMed1975

[Peripheral arterial disease and diabetes mellitus(author's transl)].

Among a group of 286 patients with atherosclerotic arterial disease 35.3% had normal carbohydrate tolerance, 28% asymptomatic (biochemical or latent), and 36.7% overt diabetes mellitus. There was a tendency towards peripheral artery involvement and a greater incidence of coronary heart disease (myocardial infarction, changes in ST-T segment) among patients with asymptomatic or overt diabetes, figures being comparable for men and women. Most of the patients with atherosclerotic arterial disease without diabetes mellitus were in stage II, while in diabetics there was a shift towards stages I and IV. There was no significant correlation between incidence, symptoms, and location of atherosclerotic arterial disease, on the one hand, and duration of overt diabetes, on the other.

Arterial Occlusive Diseases↗
PubMed1975

[Extrahepatic portal hypertension and pregnancy (author's transl)].

Taking into account 6 own cases and 51 cases reported in the literature the question is asked, whether pregnancy influences portal hypertension due to extrahepatic block and vice-versa. Complications arise in about 50% of the patients, hemorrhage from esophageal varices making up to 40%, as the most common complication. Most esophageal bleedings occur in the second of third trimenon. The physiological changes of the circulatory system during pregnancy are held to be responsible for these complications; especially temporary increase of portal pressure tend to aggravate the preexisting extrahepatic portal hypertension. The prognosis for mother and child in these cases is less severe than in patients with portal hypertension due to liver cirrhosis. Therapeutic procedures which have to be adapted to the individual case are discussed.

Adult↗
PubMed1975

Determination of the specific blood flow of the liver by inhalation of radioactive rare gases.

The technique applying the inhalation of radioactive rare gase is a new method to determine the specific blood flow of the liver. After inhalation of 133Xe, the course of activity is registered above liver and spleen as well as in the exspirated air. The perfusion is calculated from the resulting wash-out curves. The average value in healthy persons is 91 +/- 15 ml/100 g min. The reproducibility is 5 +/- 1%. The xenon wash-out is delayed in cirrhotic livers; the blood flow is significantly decreased and amounts to an average of 45 ml/100 g min. A delayed wash-out of xenon was also found in major fatty livers due to the high affinity of xenon to fat. The dependence of the partition coefficient on the fat content was investigated by Kitani and Winkler in homogenized liver tissue of different fat content. The question arises whether these in vitro findings can be transferred to in vivo wash-out curves. We therefore carried out first investigations on patients of known content of fat of the liver, applying a 85MKr-133 Xe-double measurement. According to results which have been achieved up to now, sufficient accuracy can only be obtained up to a fat content of 10%.

Fatty Liver↗