Search PubMed⌕ Search

Biomedical subjects

H Hirose

Publications and source records attributed to H Hirose.

At least 487 records · Page 27Linked to original sources

[Evaluation of prognostic factors in hepatocellular carcinoma using multiple regression analysis].

We analysed the relationship between 19 prognostic factors and the life span of patients with hepatocellular carcinoma. Among 52 patients who had been admitted to the Gifu Prefectural Gifu Hospital, in 46 the pathological diagnosis was confirmed. We selected 9 of 19 variables by the stepwise forward regression method. These were Arels Classification, ascites, HBsAg, performance status, method of therapy, sex, GOT, albumin and bilirubin. Results of multiple regression analysis demonstrated that the presence of ascites is the most important factor; other significant factors are Ariel's Classification, performance status, positivity of HBsAg, method of therapy, and GOT. These parameters were paralleled with the survival curves, most of which had been categorized. Although intra-arterial infusion of ADM was considered the most favourable treatment method, the survival curves suggested that other methods were equally effective.

Adult↗

[Long-term follow-up results after aorto-coronary bypass grafting].

One hundred and eighty-two patients had been followed for 1 year or longer after aorto-coronary bypass grafting ( ACBG ). Four of them died in this follow-up period, one due to cardiac failure, 8 years postoperatively (p.o.), two due to malignant tumor and one due to an accident. About three quarters of patients improved p.o. into NYHA functional classification I, though no patients was in NYHA I preoperatively. More than 90% of patients with successful complete revascularization in left coronary artery and with a patent left anterior descending artery (LAD), improved into NYHA I. Four patients had reoperation due to the occluded graft to LAD in 4 months to 9 years p.o.. There was neither operative death nor late death 6 months to 4 years after reoperation. Patients with successful revascularization in left coronary artery had significant improvement in left ventricular function, but with unsuccessful one had less improvement. The patients with a history of myocardial infarction in successful revascularization in left coronary artery showed remarkable improvement of ejection fraction at rest and in elevation in LVEDP at exercise. These results show myocardial infarction causes irreversible functional and morphological damage and it could not be full recovered even after ACBG .

Adolescent↗

[Current status of cardiac surgery for congenital heart disease-- tetralogy of Fallot and double outlet right ventricle].

In tetralogy of Fallot (TF) a new method of repair has been utilized since 1978. The method is transpulmonary and trans-atrial repair without or with minimal right ventriculotomy. Out of consecutive 81 patients, 79 patients underwent repair with this method with one operative death (operative mortality 1.3%). Postoperative hemodynamic evaluation revealed the better results in cardiac index, right ventricular endodiastolic volume and right ventricular ejection fraction. Also, pulmonary regurgitation has been reduced significantly compared to the conventional method with right ventriculotomy. The main criteria for total repair in TF is size of the pulmonary artery, and PA area Index (PA area/Normal R-PA area) over 0.20 is our minimal criteria to obtain postoperative right ventricular peak pressure ratio below 0.8. In double outlet right ventricle (DORV), operative mortality in last 5 years has improved to 19% (21 cases) from 68% of previous series. Six Taussig-Bing anomalies have undergone primary repair with 2 deaths. Various methods have been utilized including Kawashima 's method in 1 (0, op-death), Rastelli's method in 1(1), Hightower 's method in 1(0), and recently 2 patients had repair with Rastelli's operation with creating AP window to avoid subaortic obstruction. Also, Jatene operation (arterial switch) has been successfully performed in 8 month-old patient.

Adolescent↗