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Biomedical subjects

H Hinterhuber

Publications and source records attributed to H Hinterhuber.

86 records · Page 5Linked to original sources

[The plasma prolactin level under fluphenazine treatment (author's transl)].

An efficient treatment with psycho-drugs is essential for the initial therapy of acute schizophrenic psychoses. Also the outcome of the psychosis is largely dependent on the influence and the duration of the existing initial symptoms. Neuroleptic drugs raise the plasma prolactin level by blocking the dopamine receptors. So a valid parameter for the interference of the neuroleptics in the dopaminergic transmitter system is available. In 21 male patients the plasma prolactin levels were examined. The plasma prolactin base-lines were the same as in healthy persons. Infusions of 20 to 40 mg fluphenazine every three hours led to an average of fourfold increase of prolactin, which returned to the original level after 10 hours. The plasma prolactin level reached a plateau on the 7th day of treatment with fluphenazine dihydrochloride. Together with the stabilisation of the plasma prolactin level, which is reached more quickly with simultaneously administered fluphenazine decanoate, generally an improvement of the psychopathological condition takes place. In a comparable group of patients treated with ECT the prolactin level always returned to the initial point even after multiple administrations.

Fluphenazine↗

[The limits of social reintegration after longterm psychiatric hospitalisation (author's transl)].

In cooperation with the University Clinic for Psychiatry, Innsbruck, the social psychiatric service of the regional government of South Tyrol set up a rehabilitation programm, under which 35 longterm hospitalized schizophrenic patients with an average stay in hospital of 12,9 years have been taken over by district institutions as outpatients. The object of our investigation was to study critically the working capability and the social relations of the 35 patients, the duration of postclinical catamneses is at least 3, at maximal 25 years. The degree of obtained reintegration is documented by the working situation and the number of social contacts. The obtained extent of resocialization and the proved positive social adaptation make it sensible to start a rehabilitation even with cronical patients with hospitalisation over decades: precondition is however a continual psychiatric care and control.

Austria↗

[Social medical aspects of patients with a permanent colostomy (author's transl)].

Problems of 39 patients with permanent colostomies/ileostomies are investigated one up to seven years after having got the anus praeternaturalis. The postoperative problems of everyday life are various and often serious, they are the more severe, the less patients had been informed preoperatively and the older the patients are. Younger and more intelligent patients integrate the colostomy easier and more quickly in their everyday life. Very useful for rehabilitation is the close contact between patient and the surgeon, respectively special colostomy-consulting hours.

Activities of Daily Living↗

[Psychodynamic aspects of paraphrenia].

Proceeding from Kraeplin's original a brief summary is given of the literature about the extensive interpretations of the term paraphrenia. Our study is based on a catamnestic examination of schizophrenic diseases first acute in 1930-1940 after 30 respectively 40 years (H. Hinterhuber) and a second group of paraphrenics who at the time being have been under our control for five years. By a simplifying scheme our own conception of paraphrenia is then defined and differentiated from the paranoid schizophrenia and the development of paranoia with special reference to the characteristic juxaposition of schizophrenic symptomatic in otherwise intact personality without a noteworthy derangement of the evironmental relations. The intact personality stands in clear contrast to the only "intact outside personality' with schizophrenic derangement of the ego. Thus the paraphrenic has the possibility to withdraw to the core of his sound personality and erect a mostly stable barrier against the partly massive hallucinations on the periphery of his personality. This corresponds to a passive attitude of avoidance in the sense of behaviour psychology. As THEREFORE the paraphrenic, similar to the phobic, tends to confine the borders of his existence by an increasingly passive avoidance attitude, he tries by a systematic desensibilisation to keep the borders of existence just in the area between psychosis and sound personality and thus render the best possible extent of personality development avoiding secondary restrictions.

Behavior Therapy↗

[Headache as initial symptom of schizophrenic disease].

Initial schizophrenia was observed in 15 out of 93 out-patients being treated for cephalea in a Regional Neuropsychiatrical Department. Certain abnormal phenomena in the field of consciousness and body sensations are typical of coenasthetic schizophrenia, with vital asthenia and vegetative symptoms. Cephaleas and head dysaesthesias are reported. There is no doubt that coenaesthetic schizophrenia has many points in common with latent schizophrenia; on the other hand it is also closely linked to hypochondriac depression, the syndrome of endogenous juvenile failure, certain latent depressions, hypochondriac euphoria, vegetative and endoreactive dysthmia and pseudoneurotic schizophrenia. Personal studies of stress responses in schizophrenia, and pneumoencephalographic examinations and EEG data in the active stage suggest diencephalic alteration. For diagnostic and initially therapeutic purposes, every patient with cephalea should be examined thoroughly by the psychiatrist; in this way the number of schizophrenias identified and treated will be considerably increased.

Adult↗

[Gastric ulcers, stress and schizophrenia. Incidence of gastric ulcers in male schizophrenic patients (author's transl)].

According to the hypothesis of a biochemical disorder, we found that schizophrenic patients show a modified reaction to stress. We have checked 668 male schizophrenic patients and found 18 ulcers (2.69%) this is contrasted by the average incidence of ulcers at the rate of 10%.12 of the 18 probands had preliminary serious somatic lesions. We came to the conslusion that the hypothalamic stress response is altered: Schizophrenic patients and the normal population show a significant difference to the incidence of gastric ulcers.

Adult↗