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Biomedical subjects

H Hess

Publications and source records attributed to H Hess.

At least 127 records · Page 7Linked to original sources

[Influence of isoxsuprine HCl on blood viscosity].

A decrease of blood viscosity is a working principle in the therapy of severe disorders of arterial blood flow. Isoxsuprine-HCl was found effective in lowering the blood viscosity when given intravenously in a dose of 30 mg over 60 min. This effect derives probably from a decrease of the tendency to aggregate and an increase of the flexibility of red blood cells. 30 min after termination of the infusion this effect has its maximum and 60 min later still is significantly raised.

Blood Viscosity↗

[New possibilities for demonstration of some biogenous amines in the adrenal by X-ray microanalysis (author's transl)].

Technical possibilities for the histochemical demonstration of some biogenous amines with the scanning electron-microscope and X-ray microanalysis were shown by using argentaffine and chromaffine reactions. Objects were adrenals of adult minipigs. Beside morphologic studies the amounts of silver or chromium can be determined semiquantitatively by the intensity of the specific X-radiate from "sum up-analysis" out of punctual areas. Furthermore the high amine concentrations in the adrenal medulla permit the performance of "line-analysis" and of "element-distribution-pictures" for silver or chromium. At the points chosen for analysis the concentration of epinephrine + norepinephrine is six times as high in the adrenal medulla as in the cortex; for norepinephrine alone it is only three times higher. Line-analysis shows that the concentration of katecholamines in the cortex is very low in the periphery and high near the medulla. The chromaffine reaction for serotonin leads to a distinct chromium peak in the medulla with a distribution quotient of 4.6 : 1 versus the cortex showing that there must be remarkable amounts of serotonin in the adrenal medulla, inspite of the fact that serotonin cannot by synthetized there from its natural precursor.

Adrenal Cortex↗

[Clinical experience with Arwin (author's transl)].

Treatment of 52 cases with Arwin is reported. Convincing success was achieved in disorders of peripheral arterial blood flow in stage III (pain at rest), in which more than 80% of the patients treated became free from pain. In stage IV the success rate is barely 50%. A combination of thrombolysis with streptokinase and Arwin instead of heparin proved valuable as a primary approach in poor outflow conditions. In 4 out of 5 successful second lyses after reobliteration the vascular system remained patent under Arwin.

Adult↗

[Late lysis therapy of chronic arterial occlusion. A new way to improve results (author's transl)].

Thrombolytic therapy with streptokinase was carried out 14 days after transcutaneous catheter recanalization in 17 patients. In 7 patients there was a disintegration of the re-occlusion and a distinct widening of the lumen of the canal created by means of the catheter. Complete removal of the thrombotic material from the vessel wall could be confirmed angiographically in 3 patients.

Arterial Occlusive Diseases↗