A 4-year-old boy with infantile neuroaxonal dystrophy (INAD) showed gradual deterioration from age 9 months with seizure development at age approximately 36 months. Sural nerve biopsy performed at age 42 months confirmed INAD. The seizure, recorded by video-EEG, consisted of a series of symmetrical tonic spasms of both upper extremities after a prodrome period of staring and akinesis. Each spasm had phonation, and episodic autonomic symptoms such as hypertension and flushing of the face occurred throughout the seizure. Ictal EEG with each tonic spasm, showed diffuse 1-s, irregular sharp and high-voltage slow wave complexes followed by desynchronization.

Axons↗

PubMedDate not supplied

Leiomyoma of the rectum.

Rectal leiomyoma is a rare disease. In Japan, only 77 cases were reported before 1984. A study was carried out by compiling information from clinical cases together with two recent cases of rectal leiomyoma. The patients were mainly in their 50s to 60s with a mean age of 53.6 years. The sex ratio of males to females, was 1.5:1. The most common main complaints were anal bleeding and melena and subsequently cylindrical shaped stool or constipation, attributable to rectal stenosis. The tumors were located at 8 cm or less from the anal verge in 87% of the case. Surgery is considered the best method of treatment. Five patients noted a recurrence and three underwent extirpation as their initial operation. Although it is frequently difficult to establish whether leiomyoma is benign or malignant, small lesions (less than 2 cm in diameter) are best treated by local excision.

Adolescent↗

PubMedDate not supplied

Acute regional ileitis at Iwanai in Hokkaido--with special reference to intestinal Anisakiasis.

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Acute Disease↗

PubMedDate not supplied

The effect of pancreatectomy in lipoprotein lipase activity: an experimental study in pancreatectomized rats.

To investigate the etiology of hyperlipemia induced by total pancreatectomy in rats, the authors determined lipoprotein lipase (LPL) activity and performed the intravenous fat loading test (IVFLT). LPL activity was remarkably reduced after total pancreatectomy, but recovered almost completely with administration of 4 i.u./Kg of insulin. The results of IVFLT showed positive correlation with LPL activity changes. The elimination rate K of IVFLT also recovered with the administration of insulin. On the other hand, in our previous reports no evidence of increase in lipid synthesis in the liver of depancreatectomized rats was found. From these results, the authors tentatively concluded that the main cause of pancreatectomy-induced hyperlipemia was a delay in the removal of lipids from the blood, due to decreased LPL activity caused by a lack of insulin.

Animals↗