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Biomedical subjects

H Handa

Publications and source records attributed to H Handa.

At least 649 records · Page 36Linked to original sources
PubMed1976

Brain necrosis after repeated radiotherapy.

A case of radionecrosis in the brain simulating a tumor was presented. Two courses of radiotherapy were given to a right intraorbital tumor over an interval of ten years. Four years after the second course of therapy, symptoms simulating a right frontal lobe tumor developed. A frontal lobectomy including the necrotic area improved the patient's condition.

Adult↗
PubMed1976

Radiation-induced meningioma: with review of literature.

A case of tentorial meningioma occurring 12 years after radiation therapy for a verified craniopharyngioma is presented. The pertinent literature is reviewed and it is concluded that irradiation of the brain may be responsible for the late development of intracranial meningiomas, which are less common, however, than sarcomas. A long survival after irradiation, "misregeneration" in the chronic inflammatory processes induced by irradiation, and an immunodeficiency caused by irradiation and other factors, may play some role in developing oncogenesis.

Adult↗
PubMed1976

Posttraumatic subepicranial varix.

Two cases of subepicranial varix following injury are reported. They were associated with depressed skull fractures. Subepicranial varix is a rare and benign scalp mass, and should be differentiated from vascular anomalies of the scalp and cystic masses of the scalp communicating with the cerebrospinal space. The relationship between subepicranial varix and sinus pericranii is discussed.

Adolescent↗
PubMed1976

[Botulism].

Explore the source record for details and available documents.

Animals↗
PubMed1976

[Distribution of catecholamine containing nerve endings in the hypothalamus of the rhesus monkey].

Using the Falck-Hillarp method, the distribution of catecholamine nerve terminals in the rhesus monkey hypothalamus was studied. The distribution pattern was fundamentally similar to that in the rat, cat and human fetus; abundunt catecholamine varicosities (presumed noradrenaline nerve terminals) were observed in the dorsomedial nucleus, supraoptic nucleus, paraventricular nucleus, medial forebrain bundle, periventricular layer and internal layer of the infundibulum, while little were in the mamillary nucleus, ventromedial nucleus and anterior hypothalamic area. A band of diffuse green fluorescence (dopamine nerve terminals) was observed around the capillary loops in the external layer of the infundibulum. the discrepancy with the rat was noted in the abundunt noradrenaline nerve terminals in the suprachiasmatic nucleus and denser innervation of them in the arcuate nucleus and internal layer of the infundibulum. In addition to the noradrenaline nerve fibers from the peripheral sympathetic NA nerve, the noradrenaline nerve terminals of central origin closely approximated to the small intracerebral vessels.

Animals↗
PubMed1976

Association of brain tumor and intracranial aneurysms.

A case of association of meningioma and four intracranial arterial aneurysms including one giant aneurysm is reported, and the available literature reviewed. The operative mortality of patients with coexistence of brain tumor and cerebral aneurysm is very high (40%). When the aneurysms are multiple, eight out of ten patients expired after operation. Association of a giant aneurysm and brain tumor is exceedingly rare. The present case seems to be the fifth reported case.

Adult↗
PubMed1975

Pathogenesis of acute arterial fat deposition in spontaneously hypertensive rats.

The selectively-bred substrains of spontaneously hypertensive rats with a greater vulnerability to vascular lesions rapidly developed arterial fat deposition within 1 or 2 weeks as well as a greater hypercholesterolemic response when fed on high fat cholesterol diet including 20% of suet, 5% of cholesterol and 2% of cholic acid. The ring-like arterial fat deposition at the branches of superior mesenteric arteries and cerebrobasal arteries, which was found to be good indices for the deposition of intrarenal or coronary arteries, was not observed in normotensive rats fed on high fat cholesterol diet for 3 months, greatly delayed in SHR under antihypertensive treatment and accelerated by 1% salt loading in drinking water. The horseradish peroxidase infused intravenously 1 to 4 hours before sacrifice leaked in ring-like forms which corresponded to the fat deposit in mesenteric arteries. The incorporation of 3H-proline infused 4 hours before sacrifice was enhanced in the mesenteric arteries with the fat deposition. These results clearly indicated that hypertension was a great contributory factor to rapid arterial fat deposition, which was caused by an increased vascular permeability and enhanced the arterial collagen formation, the initiation process of arterio- or atherosclerosis.

Acute Disease↗