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Biomedical subjects

H Handa

Publications and source records attributed to H Handa.

At least 613 records · Page 34Linked to original sources
PubMed1977

Subdural haematoma (effusion) and internal hydrocephalus.

It is unusual to encounter a case where subdural haematoma (effusion and internal hydrocephalus coexist and are progressive. Often, when the two diseases are concomitantly present, the pathology of one complicated the other. The pathology of subdural haematoma (effusion), complicated by internal hydrocephalus, and problems involved in the diagnosis and treatment of such cases are described, with particular reference to three such cases treated by the authors, and a review of the literature. When cerebral angiography is used as a follow-up study for postoperative subdural haematoma (effusion), it is necessary to direct attention not only to the disappearance of the subdural clear space but also to the possibility of the occurrence of hydrocephalus. If the intracranial pressure is increased and convulsive seizures appear after a shunting operation for hydrocephalus, it is necessary to consider not only shunt dysfunction but also post-shunt subdural haematoma (effusion).

Cerebral Angiography↗
PubMed1977

Helper factor(s) for growth of adeno-associated virus in cells transformed by adenovirus 12.

Evidence is presented that a helper factor(s) for growth of adeno-associated virus (AAV) is present in cells transformed by adenovirus type 12 (Ad12). The growth of AAV was observed in heterokaryons formed by fusion of human KB and Ad12-transformed rodent cells by using ultraviolet-inactivated Sendai virus without coinfection of cells with adenovirus. The presence of the helper factor(s) for AAV growth in rat cells transformed by the EcoRI-C fragment or the HindIII-G fragment of Ad12DNA suggests that the helper factor(s) induced by infection with adenovirus is the Ad12-specific T antigen.

Adenoviridae↗
PubMed1977

Isolation of the viral DNA replication complex from adeno-associated virus type 1-infected cells.

The replication complex active in adeno-associated virus type 1 (AAV-1) DNA synthesis in vitro was solubilized, with a nonionic detergent, from the nuclei of human embryonic kidney cells coinfected with AAV-1 and an early temperative-sensitive mutant (ts125) of human adenovirus type 5 at the nonpermissive temperature (40.5 degrees C). The complex sedimented with a mean size of 23S and contained parental AAV-1 DNA. Most of the DNA synthesized with the AAV-1 DNA replication complex in vitro was AAV-1 DNA, as revealed by DNA-DNA hybridization and sedimentation in a neutral sucrose gradient. However, it sedimented in an alkaline sucrose gradient as molecules smaller than AAV-1 DNA (14.4S). The AAV-1 DNA replication complex was not formed in cells infected with AAV-1 alone.

Adenoviridae↗
PubMed1977

Abducens nerve palsy as initial symptom of trigeminal schwannoma.

The insidious onset and slow progression of symptoms may cause delay in the recognition of trigeminal schwannomas. Two cases with abducens nerve palsy as an initial symptom are reported, in both of whom the tumour was growing mainly below and anterior to the intracavernous portion of the internal carotid artery. Early detection of clinical symptoms and thorough radiological investigations are important in the early diagnosis of these lesions.

Abducens Nerve↗
PubMed1977

Hypothalamo-pituitary-adrenal function in pituitary adenoma and craniopharyngioma. Part I: Insulin test, lysine-vasopressin test, and rapid ACTH test.

For the assessment of hypothalamo-pituitary-adrenal function in the presence of pituitary adenomas and craniopharyngiomas, insulin tests, lysine-vasopressin tests, and rapid ACTH tests were performed and plasma cortisol was assayed. Rapid ACTH test and lysine-vasopressin test, which examine adrenal and mainly pituitary function respectively, showed normal function in ten among 14 cases. But insulin test, which examines the whole hypothalamo-pituitary-adrenal function, showed various levels of abnormality in eight among 14 cases. Frequent association of functional disturbances of this axis in these diseases was stressed.

Adenoma, Chromophobe↗
PubMed1977

Infratentorial retrocerebellar cysts.

Clinical analyses of ten cases of infratentorial retrocerebellar cysts were performed in order to define specific signs or symptoms and thus improve the preoperative diagnosis. There were not symptoms or signs specific for the cysts. When a tumor in the posterior fossa is suspected by ventriculography, vertebral angiography or pneumoencephalography should be performed to exclude the possibility of a cyst, particularly in patients under 20 years of age. Care should also be taken to look for supratentorial cysts, since multiple cysts are found occassionally. It is necessary to evaluate the therapeutic program for each case, depending on the relationship between the cyst and the subarachnoid space and ventricular system. Postoperative follow-up is important, especially in cases in which only excision of the cyst is performed.

Adolescent↗
PubMed1977

Hypothalamo-pituitary-adrenal function in pituitary adenoma and craniopharyngioma. Part II: insulin test and clinical features.

For the assessment of hypothalamic corticotropin releasing hormone (CRH) secretory function, insulin test, lysinevasopressin test, and rapid ACTH test were performed and plasma crotisol was assayed. Disturbances of CRH secretory activities were found not to be related with the degree of suprasellar extension of tumors, contents of tumors, the degree of visual disturbances, or the duration of symptoms, and it was supposed that more complex mechanisms were responsible for CRH secretory abnormalities.

Adenoma, Chromophobe↗
PubMed1977

Ossifying fibroma of the occipital bone.

A rare ossifying fibroma in the occipital bone is described, and the available literature reviewed. The rapid growth seen in this case was remarkable and led us to believe this was a malignant osteogenic tumor. Full knowledge and the correct diagnosis of ossifying fibroma should have prevented an unnecessarily extensive operation for this benign lesion.

Child↗