Biomedical subjects

H Höffken

Publications and source records attributed to H Höffken.

58 records · Page 4Linked to original sources

PubMed1978

[Comparison of cytological features in keratinizing dysplasia and keratinizing squamous carcinoma (author's transl)].

By means of the literature pathological aspects of the keratinizing dysplasia and the keratinizing squamous cell carcinoma are discussed. It has been tried to point out cytological criterias by means of which a differential diagnosis can be performed between the two lesions. The difficulties of this task are mentioned. To give examples for the diagnostic criterias pictures of our own material are demonstrated. Criterias for differential diagnosis of the two lesions are summarized in a table. By the use of all criterias mentioned above a differential diagnosis can be performed cytologically in most cases. Cytological findings should be described as precisely as possible. It is only in this way that the best information can be given to the clinician referring to diagnostical or therapeutical procedures that should be performed further on.

Carcinoma, Squamous Cell↗

PubMed1977

[Cytology of reversible and irreversible epithelial changes in the uterine cervix].

The etiology and the experimentally founded concept of pathogenesis of reversible and irreversible epithelial changes of the cervix uteri are described. The possibilities and limitations of differential diagnosis of dysplasia, carcinoma in situ, and invasive carcinoma are discussed. Cytological criteria of differential diagnosis are mentioned and summarized in table form. Rates of regression, persistence and progression of different forms of dysplasia as potential forerunners of invasive carcinoma are mentioned. By the use of all cytological parameters a primary differential diagnosis of the mentioned lesions may be reached to a degree of 90% (Patten 1969; Wied et al. 1976). Diagnostic findings should be precisely formulated to give the best information for further diagnostic or therapeutic procedures concerning the individual case.

Carcinoma in Situ↗

PubMedDate not supplied

Components and results of a new preparation technique for automated analysis of cervical samples.

Components and evaluations of a new preparative procedure for automated high-resolution analysis of cervical samples are presented. This procedure is based on sedimentation velocity separation of samples with subsequent fractionation of the separation column and centrifugal deposition of suspended cells on coated glass slides. A system for specimen collection and mailing of suspended samples is described. A new type of glass slide designed for automated analysis is presented, and centrifugal buckets for cell deposition on a 6-sq-cm area are described. Experimental results with different kinds of coating substances for glass slides as well as different isopyknic media are discussed, and data for differential cell counts are graphically demonstrated. Looking at the diagnostic accuracy and economic feasibility of this system, the authors realize that preparations have to be evaluated quantitatively and that constraints of sample size and processing time have to be taken into consideration for further developments.

Autoanalysis↗

PubMedDate not supplied

Cytology of a mammary carcinoma metastasis at the angle of the mandible: a case report.

Cytologic findings in a fine needle aspiration biopsy specimen of a tumor of the right angle of the mandible provided the first clues to the presence of a poorly differentiated carcinoma. Patient history, clinical course and histology suggested a metastasis of an established mammary carcinoma as the most probable diagnosis.

Breast Neoplasms↗