[Clinical and electroencephalographic study (polygraphic technic) of epileptic seizures in induced hypoglycemia].
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Biomedical subjects
Publications and source records attributed to H Gastaut.
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A study was performed on 174 epileptic patients aged of 65 years and over. This semeiology of seizures of 156 patients can be categorized according to the international Classification of the epilepsies. Correlations were made between epilepsy form and scan. We had found that majority (74%) of the patients manifested parital seizures either with elementary or a complex symptomatology. The generalized tonico-clonic seizures of the aged were less frequent: 9% consisted of partial seizures secondarily generalized, 1% of Grand Mal primary generalized epilepsies and 16% of secondary generalized epilepsies due to a cerebral involution which can be only detectable with CT-scan. By means of CT-scan we were able to define the true etiology in 63% of our patients.
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An analysis of four cases with lipomas of the corpus callosum with epilepsy and of some data in the literature has led to the following conclusions: 1) Epilepsy: a nearly constant feature is often severe always partial and begins before the age of fifteen; 2) Pathophysiology of the seizures: abandoning the classic theory that they depend upon an infiltration of the cingulate gyri by fibrous tissue growing out from the capsule of the lipoma, the authors consider that the essential mechanism is represented by the interhemispheric disconnection. This latter is responsible for a facilitory and disinhibitory action which would favour the appearance of seizures under the effects of an epileptogenic lesion, the effect of which would remain sub-threshold in the presence of an intact corpus callosum, playing its normal inhibitory role.