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Biomedical subjects

H Fischer

Publications and source records attributed to H Fischer.

At least 541 records · Page 30Linked to original sources
PubMed1976

Studies on the activation of mouse bone marrow-derived macrophages by the macrophage cytotoxicity factor (MCF).

The capacity of bone marrow-derived macrophages to be rendered cytotoxic by macrophage cytotoxicity factor (MCF) at different stages of maturation was tested. Under in vitro conditions not only mature macrophages but also nonadherent precursor cells were successfully activated. Mature adherent bone marrow macrophages can be rendered cytotoxic for up to three weeks in tissue culture. Cytotoxic effects are demonstrable even at a killer target ratio of 0.5:1. Granulocytes do not respond to activation with MCF. Bone marrow-derived macrophages can be collected at early stages of maturation, when they grow in suspension or have developed only loose adherence. Macrophages which have differentiated in vitro from bone marrow never show any signs of nonspecific activation as measured by our cytotoxic assay system.

Animals↗
PubMed1976

Tissue iso-renins.

1. Several extrarenal tissues contain enzymes which are similar to kidney renin: they hydrolyse angiotensinogen to form angiotensin I; they have characteristic substrate specificity; the physicochemical properties of kidney renin and of extrarenal tissue iso-renin are similar. 2. Results indicate that tissue iso-renins are part of a complex enzyme system with mainly local function. A possible biological role has been demonstrated in brain, adrenal gland and tissue culture.

Adrenal Glands↗
PubMed1976

[Barotrauma].

Explore the source record for details and available documents.

Altitude Sickness↗
PubMed1976

[Comparative morphometric investigations for the determination of the degree of stenosis of the femora artery (author's transl)].

Planimetry, point-counting-technique and gravimetry were tested for their suitability for determining the degree of stenosis on the same material, the arteria femoralis dextra out of 103 unselected obduction cases. Pilot studies on the circle showed the planimetric method to be most accurate. On transverse sections of the femoral arteries the results of the point-counting-technique deviate significantly stronger from the planimetric test results in comparison with those of the gravimtric method. The point-counting-technique shows the smallest, the gravimetric method the highest time expenditure. Attention is drawn to the necessity of taking into account the plane of the intact intima when determining the degree of stenosis. Also in the case of high-grade stenoses there are frequently no clinically conspicous disturbances of the blood flow.

Adult↗