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Biomedical subjects

H Evers

Publications and source records attributed to H Evers.

At least 73 records · Page 4Linked to original sources
PubMed1980

A lidocaine-prilocaine cream for superficial skin surgery and painful lesions.

A eutectic mixture of lidocaine and prilocaine in a water emulsion cream base produces effective superficial dermal analgesia when applied under occlusive dressing for 60 minutes. On the genitals, lips and oral mucosa, the application time can be reduced. The cream was found to be an effective alternative to conventional infiltration anesthesia for dermabrasion and superficial surgical procedures. It is especially useful in children for the removal of molluscum contagiosum and prior to venepuncture. The preparation is also an effective pain reliever when used on certain ulcerations.

Administration, Topical↗
PubMed1979

Local effects produced on intact skin by epicutaneously applied anaesthetic formulations. An experimental study in man.

By means of experiments involving pin-pricking, compositions containing 10% ketocaine base in a mixture of 2-propanol, glycerol and water were found to produce a high frequency of block to cutaneous pain following application to volunteers under an occlusive dressing. The local analgesic efficacy was found to be directly related to the degree of saturation of ketocaine in the vehicle and time of application. The degree of hyperaemia observed in the treated skin areas was found to be related to the degree of local analgesia produced.

Adult↗
PubMed1979

Inhibition of hyperhidrosis by topical application of a local anesthetic composition.

An eutectic mixture of 5% lidocaine and 5% prilocaine applied locally to the skin inhibited epinephrine-induced sweating in healthy subjects. It also inhibited palmar and axillary hyperhidrosis from 1 to 6 hours after application to 15 of 17 patients tested. A placebo lotion was without effect. When used daily for 3--4 weeks, only 25% of the patients were very pleased with the treatment. The reason for the decrease of efficacy is uncertain.

Administration, Topical↗
PubMed1976

[Relevance of width measurements of the right pulmonary artery descending branch for detection of pulmonary hypertension in chronic obstructive lung diseases (author's transl)].

363 patients with chronic obstructive lung diseases were examined regarding the relation between pulmonary hypertension and width of the right descending branch of the pulmonary artery (RDB). There was found a high significant correlation between mean pulmonary artery pressure at rest and diameter of the RDB. The width of RDB was not so close correlated with pulmonary artery pressure during exercise. If the diameter of the RDB was 19 mm and more, a manifest pulmonary hypertension was stated nearly always. Missing this radiological sign doesn't exclude pulmonary hypertension. The method will be useful for screening a risk group "pulmonary hypertension". All cases selected by this method aught to be examined by means of right heart catheterization with the floating technic.

Adult↗
PubMed1975

Pain and temperature sensations related to local analgesia.

Following the injection of local analgesic solutions at room temperature (21 degrees C) and at normal body temperature (37 degrees C), respectively, in the oral submucosal region, it was found that most of the subjects experienced the solutions as being of body temperature, regardless of whether the temperature of the solution was 37 degrees C or 21 degrees C. The duration of soft tissue anesthesia was not influenced by the temperature of the solutions. After the anesthetic effect had subsided, prilocaine 4% caused post-analgesic pain less frequently than did lidocaine 2% with adrenalin 12.5 mug/ml. Following injections with different mepivacaine solutions it was found that a low pH caused more frequent pain than a high pH, that the addition of a vasoconstrictor caused more frequent pain than a plain solution, and that there was a tendency for more frequent pain with increasing concentrations of the local anesthetic agent. In this study the addition of adrenalin was not found to prolong the period of soft tissue anesthesia.

Adult↗