Search PubMed⌕ Search

Biomedical subjects

H Ellis

Publications and source records attributed to H Ellis.

At least 217 records · Page 12Linked to original sources
PubMed1978

Colonic anastomosis healing. The effect of topical povidone-iodine.

The effect of povidone-iodine (0.1% available iodine) irrigation on colonic anastomosis healing was investigated in 196 Sprague-Dawley rats. Each end of the divided colon was irrigated with 5 ml of povidone-iodine solution or with an equal volume of normal saline before anastomosis and again after the anastomosis had been completed. Healing was assessed at 2, 4, 6, 8, 10, and 14 days after operation: macroscopically, mechanically, histologically and angiigraphically. Povidone-iodine irrigation did not impair healing in any way.

Administration, Topical↗
PubMed1978

Self-established porto-caval and porto-pulmonary shunts in mechanically induced portal hypertension. An experimental study.

Portal hypertension was mechanically induced in rats by partial constriction of the portal vein. Angiography revealed the spontaneous development of porto-systemic and porto-pulmonary shunts in all hypertensive animals. A coincident decompression of the portal system was recorded. Release of the portal vein constriction led to disappearance of the collaterals in most of the experimental animals.

Animals↗
PubMed1978

Hydradenitis suppurativa.

The surgical treatment of a group of 24 patients with hydradenitis suppurativa is described and the clinical features, aetiological factors and other methods of treatment are reviewed. An abnormally high incidence of atopy is noted within the group.

Adult↗
PubMed1977

Does the peritoneum need to be closed at laparotomy?

Closure of vertical laparotomy wounds was randomized between a two-layer technique of continuous catgut to peritoneum and continuous nylon to sheath and a one-layer technique in which the peritoneal suture line was omitted. In 162 two-layer closures there were 4 burst abdomens and 7 wound hernias (6.8 per cent wound failures); in 164 one-layer closures there were 5 burst abdomens and 7 hernias (7.3 per cent failures). Of 21 patients in this series with jaundice, the abdominal wounds dehisced in 3, and 4 patients developed incisional hernias (33.3 per cent failures) compared with a 5.2 per cent failure rate in the 305 non-jaundiced patients (P less than 0.01). Closure of the peritoneum as a separate layer, as widely advised and practised, appears to play no significant role in the healing of the laparotomy wound.

Animals↗
PubMed1977

Cue saliency in faces as assessed by the "Photofit" technique.

The present study attempted to assess the relative salience of different parts of the human face through the manipulation of the features contained in the Photofit Kit. Subjects observed a face constructed from the kit before attempting to identify the same face in an array of alternatives. The alternatives differed from the target in only one feature and this was systematically varied within the array. Nose changes were least likely to be noticed, followed by mouth and eyes, with foreheads producing the lowest rate of error. This order of features held irrespective of the similarity of the distractors or whether judgements were made in the presence or in the absence of the target. The chin region produced different results depending upon the similarity of the distractors. The results are discussed in relation to earlier experiments in which Photofit and previous studies of cue saliency were used.

Cues↗
PubMed1977

Wound healing.

An account is given of the methods used and the results obtained in a series of experimental studies, carried out over the past 15 years, of the effects of various factors on the healing of abdominal wounds in animals. The factors examined include uraemia, jaundice, infections, and the technique of wound closure. The preliminary findings in a comparison now in progress of the results of one- and two-layer closure of laparotomy wounds in human patients are also given. The relative neglect of the study of wound healing in the past is emphasized and some aspects that are in urgent need of further investigation are mentioned.

Abdomen↗
PubMed1976

Jaundice and wound healing: an experimental study.

Obstructive jaundice was induced in rats by ligation and division of the common bile duct. The healing of a standard gastric incision and a parietal peritoneal defect in these animals showed histological evidence of delayed healing compared with controls. The bursting strength of the abdominal incision was also lowered, but not that of the stomach, probably because of the adhesions which reinforced the gastric incisions. Angiography did, however, reveal delay in angiogenesis in the gastric wounds of jaundiced animals. The possible causes of this delay in healing and its clinical implications require further investigations.

Abdominal Injuries↗
PubMed1976

The peritoneal reaction to starch and its modification by prednisone.

A saline suspension of 1.5 g of starch powder (Biosorb) inoculated into the peritoneal cavity of rats produced a massive granulomatous reaction which persisted for up to 18 months. From 15 months onwards, starch particles could only be detected with PAS staining. Prednisone at a dosage of approximately 1 mg/kg daily by the oral route produced significant reduction of this phenomenon only when commenced 2 weeks before inoculation. Therapy commenced at the time of starch inoculation had only a minor effect on this response, but if commenced 2 weeks after inoculation failed to ameliorate the granulomatous reaction.

Animals↗
PubMed1976

An experimental study of gastric healing following scalpel and diathermy incisions.

To date there has been no reliable information available which compares gastric healing following incisions made by scalpel and diathermy. Standard incisions were made in rat stomachs, half with a scalpel and half with diathermy, following which they were closed in a standard fashion. Healing was assessed at intervals by bursting and tensile strength measurements, angiography, and histology. All incisions were healed by the tenth day. The only significant difference discovered was that histologically there was a definite lag in healing up to the fifth day in those incisions made by diathermy. It is suspected that this is due to mucosa having been dragged into the wound edges by adherence to the diathermy knife.

Animals↗
PubMed1976

Gastric mucosal contraction.

In this study the role that contraction plays in the healing of gastric wounds is explored experimentally. Superficial gastric mucosal defects made in the columnar part of rat stomachs were found to close rapidly, compared to defects carried down into the muscle layer. The collagen was packed tightly at the edges of the defects and no other factors appeared to have played a part in the closure. It is surmised that the decrease in size of the defect is due to fibroblastic activity causing contraction. It would seem likely that the myofibroblast, as described by other investigators, would be the unique cell causing this action. Further studies are required to confirm or refute this hypothesis.

Animals↗
PubMed1976

The surgical treatment of hyperhidrosis.

The diagnosis of primary hyperhidrosis is one of exclusion, but it is not a difficult one to make. It is a common, embarrassing and even disabling condition. If it does not respond to simple conservative therapy, the practitioner should not hesitate to advise sympathectomy for hyperhidrosis of the upper or lower limbs, or some simple local operation on the affected skin area for localized excessive axillary sweating.

Adolescent↗