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Biomedical subjects

H Ellis

Publications and source records attributed to H Ellis.

At least 199 records · Page 11Linked to original sources

The effect of uraemia upon wound healing: an experimental study.

Acute uraemia was induced in rats by performing a 70 per cent nephrectomy. Uraemia was shown to delay the healing of intestinal anastomoses and abdominal wounds in rats as judged by bursting strength tests. Cellular proliferation was depressed at wound edges but there was no reduction in the total amount of hydroxyproline present in the wounds. Fibroblast growth in tissue culture was affected by the addition both of uraemic plasma and of urea solution to the culture medium. The possible causes of these effects are discussed.

Abdominal Muscles↗

Extra-cranial aneurysm of the internal carotid artery treated by proximal ligation.

A case of aneurysm of the extra-cranial section of the internal carotid artery extending to the base of the skull is described. Treatment comprised proximal vessel ligation, the tolerance of the patient's cerebral circulation to this procedure first being assessed by measuring the back pressure across the circle of Willis after temporary carotid artery occlusion. The value of this technique is discussed.

Aneurysm↗

Axillary hyperhidrosis - topical treatment with aluminium chloride hexahydrate.

Forty-two patients with axillary hyperhidrosis on the waiting list for surgery were treated with topical saturated solution of aluminium chloride hexahydrate in absolute alcohol. There have been 7 failures. Three patients were unable to cope with the treatment and 4 more experienced severe local irritation or soreness; these 4 were submitted to local surgery. This is a simple and effective treatment for the majority of cases of severe axillary sweating.

Administration, Topical↗

Transaxillary sympathectomy in the treatment of hyperhidrosis of the upper limb.

Idiopathic (primary) hyperhidrosis is a common and distressing condition. Excessive axillary sweating responds to local excision of the eccrine glands. In severe cases, sympathectomy may be indicated to deal with hyperhidrosis of the hands and feet. The surgical anatomy of transthoracic sympathectomy is described.

Adolescent↗

Topical noxythiolin in colonic healing.

Rats were subjected to division and anastomosis of the colon just proximal to the rectum to study the healing of colonic anastomoses. The effect of noxythiolin irrigation of the divided colon before and after anastomosis was investigated and compared with controls. Healing was assessed using five variables--macroscopic and microscopic inspection, bursting pressure and tensile strength estimations and angiography for new vessel formation. The study shows that noxythiolin irrigation of the colon in the rat significantly increases the chance of a sound anastomosis without interfering with healing. Furthermore, it inhibits the formation of adhesions.

Administration, Topical↗

Effect of various pyloroplasties on fecal fat excretion in dogs and humans.

Fecal fat excretion has been measured both before and after truncal vagotomy and pyloroplasty in patients with chronic duodenal ulcer, and pyloroplasty alone, in dogs. In 13 patients the mean increase in fecal fat after truncal vagotomy and Heineke-Mikulicz pyloroplasty was 2.34 g/24 hr. After truncal vagotomy and Finney pyloroplasty in 12 patients the increase was similar and was 3.09 g/24 hr. Fecal fat was also measured before and after a 3-cm, a 6-cm Heineke-Mikulicz, and a Finney type of pyloroplasty in dogs. The area resulting from the pyloroplasties was measured. Pyloroplasty by itself resulted in a significant increase in fecal fat but no correlation could be found between the magnitude of the increase and the area that resulted from the pyloroplasties.

Animals↗

Effect of heat treatment of human milk on absorption of nitrogen, fat, sodium, calcium, and phosphorus by preterm infants.

Seven very low birthweight (less than 1.3 kg) preterm infants, aged between 3 and 6 weeks were fed raw, pasteurised, and boiled human milk for 3 consecutive weeks. Serial metabolic balance techniques were used to assess the absorption and retention of calcium, phosphorous, sodium, and nitrogen, and the absorption of fat. Fat absorption was reduced by approximately one-third when raw milk was heated. It is suggested that the improved fat absorption from the raw milk may be related to the preservation of milk lipases. A reduction in the amount of N retained was also noted when the infants were fed boiled milk. There were no obvious differences in the absorption of N or the absorption and retention of Ca, P, and Na between the three milks. All infants gained weight most rapidly during the week in which they were fed raw milk. The mean weight gain during this time was approximately one-third greater than that during similar periods when pasteurised or boiled milk was administered

Body Weight↗

Relationship of the constituents of bile to biliary peritonitis in the rat.

The local action of bile salts has been associated with a wide variety of gastrointestinal diseases. This paper describes an animal model to determine which of the major solid components of bile are responsible for peritoneal destruction in biliary peritonitis. In the rat, bile salts within the peritoneal cavity cause peritonitis but cholesterol and lecithin are without deleterious effect.

Animals↗

Achalasia of the cardia in elderly patients.

Achalasia of the cardia frequently presents as dysphagia in middle age. In the elderly, dysphagia is usually due to a neoplasm of the oesophagus or cardia. The authors have been interested to see five patients over the age of 70 presenting with oesophageal symptoms due to achalasia which is uncommon in this age group and may be mistaken for neoplastic disease.

Aged↗