Search PubMed⌕ Search

Biomedical subjects

H Denolin

Publications and source records attributed to H Denolin.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Contra-indications to sports activities in cardiac patients].

The cardiologist is faced with the problem of eliminating a subject with heart disease from a sports competition and of prescribing beneficial physical activity to patients with heart disease. The difficulty in the prescription (or contra-indication) is due to the need for an individual assessment of each case. Several general rules can be proposed for cases of heart disease with a high risk of mortality or with a poor haemodynamic status. In most cases, the beneficial or detrimental effect can not be predicted. In this review, the authors present various approaches, based on data from the literature, for different types of heart disease and for different sports. They conclude that each case requires a thorough investigation in order to reduce the number of victims of the sports stadium.

Adult↗
PubMed1984

Mechanism of pulmonary arterial hypertension.

Pulmonary circulation in the adult is a low pressure, low resistance system. Among the factors able to influence pulmonary arterial pressure the most important are hydrostatic pressure, intraalveolar pressure, left atrial pressure and alveolar gases, whilst the role of vasomotor tone is relatively limited. Granted that various hypertensive mechanisms can work jointly, the main forms of pulmonary arterial hypertension are the "passive" or "postcapillary" variety characterized by an elevated wedge pressure and the "precapillary" variety associated with a normal wedge pressure. The "precapillary" variety may be subdivided into hypertension due to increased blood flow, "obstructive" hypertension (e.g. thromboembolism), reactive hypertension (due to alveolar hypoxia) and hypertension transmitted from the bronchial circulation (bronchiectases?). In chronic lung disease pulmonary arterial hypertension is partly fixed and partly reversible.

Arteries↗
PubMed1983

Effects of molsidomine on exercise tolerance in patients with coronary heart disease.

We performed a double-blind crossover study with molsidomine in 10 patients with coronary heart disease. A single dose of molsidomine and placebo were given sublingually 1 hour before an exercise tolerance test. Molsidomine significantly reduced systolic blood pressure at rest and at all work-loads. There was also a significant reduction in electrocardiographic ST-segment depression at submaximal exercise. At maximal exercise the drug significantly increased symptom-limited oxygen consumption and total mechanical work. Molsidomine could prove useful in the treatment of angina pectoris. It has no adverse effects on pulmonary function.

Aged↗
PubMed1983

Type A in relation to job-stress, social and bioclinical variables: the Belgian Physical Fitness Study.

The present study focuses on the relationship of Type A behavior, a suspected coronary-prone behavior pattern in its overall or specific aspects, to "stress" experienced at work, and to social and coronary bioclinical risk factors. In order to measure Type A behavior and Job-Stress, respectively, the Jenkins Activity Survey Questionnaire (J.A.S. for employed persons, 1969 version) and a self-constructed Job-Stress Questionnaire were administered at a base-line examination to 2,302 men aged 40-50 years. The multivariate analysis shows: A strong Type A behavior-Job-Stress relationship; An important relationship between employment grade, educational attainment and--to a lesser extent--, marital status and, overall Type A behavior, Speed and Impatience and Job-Involvement, A weak relationship between cholesterol and triglycerides (not found in univariate analysis), and, overall Type A behavior; a small weak relationship between smoking habits, and, Speed and Impatience and Hard-Driving. A direct relationship between heavy physical activity during leisure-time and Job-Involvement.

Adult↗
PubMed1983

Effects of nifedipine on ventilation/perfusion matching in primary pulmonary hypertension.

The effects of nifedipine on hemodynamics and pulmonary gas exchange were investigated in two patients with primary pulmonary hypertension. After 20 mg of the drug taken sublingually, pulmonary and systemic vascular resistances decreased, cardiac output increased, and blood oxygenation was improved. As assessed by the multiple inert gas elimination technique, nifedipine induced a deterioration in ventilation/perfusion (VA/Q) relationships consisting in an increased perfusion of units with low VA/Q. In spite of this negative effect on gas exchange, arterial PO2 increased as a consequence of increased mixed venous PO2 in relation to an augmented cardiac output, and in one patient there was a decrease in the secondary atrial shunt. Both patients were clinically improved by the nifedipine as a long-term treatment.

Female↗
PubMed1981

Physical activity, physical fitness and cardiovascular diseases: design of a prospective epidemiologic study.

From November 1976 to September 1978, a total of 3,179 active men, 40-55 years old, were screened for established or possible risk factors. Standard questionnaires were administered to assess psycho-social behavior and physical activity on and off the job. Physical fitness was determined by means of a graded sub-maximal exercise test. Information on coronary heart disease incidence will be collected over a 6-year period. The main objective of the study is to establish prospectively if physical activity and/or physical capacity are independent risk factors. Intercorrelations between fitness, physical activity and other measured variables will bae analyzed. Doppler ultrasound and 24-hour ECG recording for detecting peripheral vascular disease and rhythm disturbances have also been used; their value and role in screening for cardiovascular disease is further discussed.

Adult↗
PubMed1981

Physical activity and physical fitness levels of Belgian males aged 40-55 years.

Physical activity during leisure time and on the job have been measured with standardized interview techniques in 1,513 normal men, aged 40-55 years, who were regularly employed in different industries. Physical fitness was simultaneously estimated by measuring the work load at which a heart rate of 150 bpm was reached on a standardized exercise test. The median energy expenditure from leisure time activities above the basal metabolic rate was 195 kcal/day; 19% of these activities were classified as heavy, 37% as moderate and 43% as light intensity. The median energy expenditure from job physical activity was 1,676 kcal/day including basal metabolic rate. The median physical fitness level was 125 W. The leisure time activity score was significantly related to physical fitness through the light and the heavy intensity subscores. Independently, job physical activity was also significantly related to physical fitness. However, both activity scores accounted for only 2% of the variance in physical fitness. The data illustrate an overall low energy expenditure profile of middle-aged normal men and a low order relationship between physical activity pattern and physical fitness.

Adult↗