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Biomedical subjects

H Denolin

Publications and source records attributed to H Denolin.

At least 19 recordsLinked to original sources
PubMed1979

Postinfarction exercise capacity after lidoflazine treatment or physical training.

44 male postinfarction volunteers were divided into 4 groups and submitted to performance tests. Groups I and II consisted of 24 patients, 12 of whom followed a 2-month physical training program, while the other 12 served as controls. Groups III and IV (10 patients each) were included in a 10-month double-blind crossover study with lidoflazine 240 mg/day vs. placebo. The cardiovascular adaptation of the patients treated for 5 months with lidoflazine had two features in common with that observed after 2 months of physical training, namely an increase in maximal exercise capacity and, during submaximal exercise tests, a decrease in heart rate compensated for by an increase in stroke volume. In contrast to physical training, treatment with lidoflazine did not improve the peripheral oxygen consumption by the muscles.

Blood Pressure↗
PubMed1979

Functional evaluation of a physical rehabilitation program including breathing exercises and bicycle training in chronic obstructive lung disease.

20 patients suffering from chronic obstructive lung disease (COLD) were submitted to a 6-month rehabilitation program including breathing exercises only (A) or coupled with bicycle training (B). Functional results obtained at rest were the following: for A: nonsignificant changes in FRC, RV, FEV1, Raw, Pa O2, pH, Pp, VO2 max SL but significant changes (p less than 0.05)for TLC (+ 214 cm3), VC (+ 171 cm3), DL CO (+ 1.79 ml), Pa CO2 (-2.9 mm Hg). For B: similar changes as for A with additional significant changes in PaO2 (+ 7.4 mm Hg) VO2 max SL (+ 250 ml) and Pp (-4 mm Hg). These results, although minimal, are attributed to improved respiratory muscle strength and improved alveolar ventilation. Exercise training adds an increased ability to sustain higher loads.

Breathing Exercises↗
PubMed1979

Intermittent claudication--epidemiology and natural history.

Epidemiological information on the prevalence, incidence and natural history of intermittent claudication and peripheral vascular disease is limited, partially by the limitation of techniques of their study. The available data from the literature are review and supplemented by results from an on-going survey the ankle blood pressure measurement with Doppler ultrasound.

Adult↗
PubMed1977

[Appearance on effort of an image of a sub-epicardial lesion in the absence of signs of myocardial necrosis. Clinical, electrocardiographic and coronographic studies of 10 cases].

A clinical, electrocardiographic and coronarographic study of ten cases shows that surelevation of ST-segment during exercise (without any signs of infarction) correspond to very different clinical situations of anatomical state of coronary vessels, occurrence of coronary spasm and evolution of the ischemic disease. "Inversed coronary Insufficiency" is proposed to design this syndrome. Practical recommandations are formulated.

Adult↗
PubMed1977

[Experimental models for the pharmacologic study of anti-arrhythmia drugs].

In order to assess the value and therapeutic safety of an antiarrhythmic drug, it must be submitted to multiple tests, which reproduce as faithfully as possible the conditions observed in human pathology. The main experimental approaches are presented here: screening and control tests. For each test, the authors emphasize the various experimental factors limiting their interpretation and allowing the extrapolation to men.

Aconitine↗
PubMed1977

Influence of short-term physical training on exercise tolerance after myocardial infarction.

14 patients with stabilized myocardial infarction were submitted to a functional evaluation before and after 3 sessions of interval training on the bicycle ergometer. With submaximal exercise, myocardial load decreases after short-term training, the heart rate and the blood pressure--heart rate product being significantly lower for the same oxygen consumption. Maximal working capacity, expressed in watts or oxygen consumption, increases significantly after short-term training, the benefit being one-third of that obtained after 6 weeks' training. These early changes in functional capacity are positively correlated with those obtained by a more prolonged rehabilitation program. Leg muscular blood flow during submaximal and maximal exercise tends to increase after short-term training, although this change is not systematic and thus not significant.

Adult↗
PubMed1976

Introduction.

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Animals↗