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Biomedical subjects

H Busse

Publications and source records attributed to H Busse.

At least 181 records · Page 10Linked to original sources

[Malformation of the tear ducts associated with clefts in the face (author's transl)].

A case of malformation of the tear duct associated with clefts in the face is described. To our knowledge this combination has not been described before. The whole symptoms complex consisted of: bilateral cleft lip upper jaw and gum, choanalatresia, mucocele of the left nasal cavity from adhesions of the lower concha with the nasal septum, cystic dilatation of the tear sac at the connection to a bony naso-lacrimal duct. Right inguinal hernia, syndactyly of the first and second left toes, iris-chroid coloboma right with congenital cataract and unilateral right convergent squint. Because of the advanced dacryocystitis on the basis of the congenital dacryostenosis, and external dacryostorhinostomy (modified after Kaleff 1937) was performed after pre-treatment by instillation of antibiotic solutions in the tear ducts. At the same time the nasal cavity mucocele was opened by partial excision of the lower concha and opening the choanal atresia. After a post-operative course free of complications and with clear patency of the tear ducts the oral surgical operation was done--closure of the face clefts. The chromosome analysis was normal the only abnormal result here was an unexplained slow rate of multiplication of lymphocytes in four cultures inoculated at various points of time. Because we could not find any hereditary factors, this symptom complex is probably due to exogenous embryo damage during the early development phase.

Abnormalities, Multiple↗

[On the operative treatment of tear opening atresia (author's transl)].

The authors describe a method of identifying and opening tear canaliculi when the openings are closed. For this purpose the common canaliculus under the medial palpebral ligament by the lateral wall of the tear sac is exposed by lamellar dissection under the microscope and opened. The roof of the tear point (where the tear opening should be) is excised over conical sounds laid retrogradely. Finally a vein catheter is placed from the upper and lower tear duct openings through the tear sac into the nasal cavity and left in situ for 12 weeks.

Child↗

[Misdiagnosis of "chalazion" (author's transl)].

The diagnosis of the often occurring "chalazion" usually puts no problems in diagnostic and therapeutical view. It must be considered, however, that already small particularities of the clinical findings point to other i.e. benign or even malignant processes. An analysis of a number of cases from 1969 to 1975 of the University Eye Clinic Münster showed in 21 out of 89 histologically examined tissue specimen another diagnosis. In 8 patients a malignant degeneration of tissue was histologically stated. The authors describe some cases, where during a longer period of time the malignant character of the disease was not diagnosed due to the misdiagnosed "chalazion".

Aged↗

[Clonidine as ointment (author's transl)].

From 15 eyes in 12 patients with chronic simple glaucoma a comparison of the IOP-diminishing effect between 1 drop 0.25% aqueous solution of Clonidine and a 2 cm long application of 0.2% Clonidine-ointment was made with special regard of local and general side effects, especially on the blood pressure. The reduction of the IOP and the blood pressure was greater and of longer duration after ointment application has a definite depôt-effect. Older patients should be fully digitalized beforehand in order to support the cardiovascular system during Clonidine application.

Adult↗

[Pilocarpine as a diagnostic agent for early recognition of a tendency to glaucoma. (Comparable results between Hollwich's pilocarpine-test and tonography) (author's transl)].

In a group of 20 patients Hollwich's pilocarpine-test and tonography were performed repeatedly at regular intervals, for diagnostic purposes. The results of the pilocarpine-test were compared with those of tonography. Hence it was shown, that the pilocarpine-test performed at the peak of the daily pressure curve, gives comparable results to tonography and hence can be useful when glaucoma suspicion exists in the eye-doctor's surgery.

Glaucoma↗

[Non-pigmented extrabulbar sarcomas of the eye-region (author's transl)].

The authors report on 30 cases with non-pigmented extrabulbar sarcomas of the eye-region which occurred in our clinic within the period of 1955 till 1975. The primary sarcomas of the orbit predominate with 11 cases over the secondary involvement with 9 cases. More seldom (5 cases) is the involvement of the lids and the epibulbar space. The various groups of lymphosarcoma predominate with 16 cases over the spindle-cell sarcoma with 6 cases. The age distribution shows that these tumors prefer the first three decades and the fifth and the following decennia. The prognosis is bad for the conservation of the eye as well as for the preservation of life. With reference to the localisation the distribution at the time of the beginning of the therapy as well as the histological findings an intensive therapy (operation, radiation, chemo-therapy) has to be accomplished.

Adolescent↗

[Anterior-cleavage-syndrome (author's transl)].

The authors report on local and general changes in dysgenesis mesodermalis iridis et corneae Rieger on the basis of own observations and literature survey. This genetically caused inhibitory deformation is outlined with regard to the differential diagnosis of other anomalies in the angle part of iris. The conservative and surgical therapeutic experiences of other authors are contrasted with our own.

Abnormalities, Multiple↗

[Plasmocytoma of the orbit (author's transl)].

After a survey of the clinical picture of plasmcytoma including histological, internal and radiological findings the special aspects of affections of the orbit are described and demonstrated by four own cases since 1955. The authors propose the differentiation between plasmocytomas with bony erosive changes, solitary or multiple, and extrameudllary myeloma for theapeutical and prognostical reasons. The extramedullary myeloma of the orbit has a better prognosis and should be treated by local excision of the tumor with following radiation (CO-60). In case of bony erosive changes the extension of the tumor has to be considered, in case of multiple involvement of the body the radiation should be prefered as a palliative treatment in combination with chemotherapy.

Aged↗

[One year's experience with pilocarpin-ocusert in the therapy of glaucoma (author's transl)].

The authors report on their own treatment results with the drug carrier Ocusert (Federal Rep. of Germany: Chemie Grunenthal). Furthermore the effect on the IOP and the compatibility including the accomodative myopia is discussed. The effect on IOP was approximately equal to Pilocarpine 2% four times daily. The accommodation myopia was significanly less than using Pilocarpin drops. A short time after insertion the conjuntiva was irritated but the irritation faded within a short time.

Clinical Trials as Topic↗