Search PubMed⌕ Search

Biomedical subjects

H Brynger

Publications and source records attributed to H Brynger.

At least 145 records · Page 8Linked to original sources
PubMed1980

Steroids and rejection treatment in the Gothenburg transplant programme.

Our experience from the Gothenburg material indicates that the graft prognosis is highly dependent on pretransplant blood transfusions, to a lesser degree on avoidance of two mismatches for the HLA-B-locus and, not the least, on the use of methylprednisolone antirejection therapy. It seems that a rather moderate dosage of methylprednisolone allows us to prolong and repeat the courses according to individual needs, and this may be the main reason for the significantly improved graft function at one year. The experiences gained and the lessons learned from the transplant programme in Gothenburg have resulted in 70% of the uraemic patients in the Gothenburg region being alive with functioning renal transplants.

Antilymphocyte Serum↗
PubMed1980

Outcome of repeated renal regrafting.

Fifteen patients underwent renal transplantation 4 and in one case 5 times. 7/15 grafts (47%) survived more than one year. The one year graft loss due to rejection was 40%. Seven patients are currently alive -- five with excellent graft function and optimal rehabilitation. Two patients are back and well on dialysis. Standard operation technique worked well in all cases. In our opinion repeated renal regrafting is a well worthwhile procedure.

Adult↗
PubMed1979

Extracorporeal surgery and autotransplantation for carcinoma of the pelvis and ureter.

Multiple transitional cell tumours of the renal pelvis and proximal ureter of a solitary kidney were successfully managed by total ureterectomy, extracorporeal subtotal resection of the renal pelvis, autotransplantation, and calicovesicostomy. The method permits resection of a maximum of the uroepithelium of the upper urinary tract at the same time as it preserves available renal parenchyma. It also implies a new and exciting approach to the renal pelvis for endoscopic postoperative control and local treatment of the malignancy.

Carcinoma, Transitional Cell↗
PubMed1979

Renal transplantation in insulin-treated diabetics.

In our view, renal transplantation in the uremic diabetic patient is justified. Recipients should be selected with caution. Patients with both loss of vision and heart disease will only rarely benefit from renal transplantation. Living related donor should be preferred if possible.

Adult↗
PubMed1978

Renal graft rejection and blood transfusion before and during the transplant operation.

The outcome of 390 consecutive primary cadaveric renal transplantations in a single centre was studied with regard to blood transfusions before and during the transplant operation. The graft loss due to rejection was 38% at 12 months in the transfused group compared to 67% in the non-transfused group (p less than 0.0005). When peroperative transfusions were added to patients in the previously transfused group, the graft loss was reduced to 34% compared to 50% if no peroperative blood was given (p less than 0.05).

Blood Transfusion↗
PubMed1977

The importance of HLA matching in primary cadaveric kidney transplantation in Gothenburg.

The importance of HLA matching was studied for 319 primary cadaveric kidney transplantations during the period 1969-1976. During 1969-1972 the HLA match was the basis for recipient selection and most cases belonged to match grade 0 or 1. Graft survival was significantly better for match grade 0. Within match grade 1 cases with one foreign HLA B antigen had lower graft survival than cases with one foreign HLA A antigen, indicating the importance of the HLA B series. During 1973-1976 the HLA match was hardly considered in recipient selection. HLA matching during this period seemed to be of less importance, except for match grade 0 and the totally mismatched cases. When matching was performed for the HLA B series, it was found that graft survival was significantly improved when no or only one foreign HLA B antigen was present. The prognosis for cases with foreign HLA B antigen was significantly better during the later period.

Cadaver↗