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Biomedical subjects

H Brody

Publications and source records attributed to H Brody.

At least 163 records · Page 9Linked to original sources

Elastic tissue in pseudoxanthoma elasticum. Ultrastructural study of endocardial lesions.

A 56-year-old woman had pseudoxanthoma elasticum (PXE). Ultrastructural findings in the endocardium showed increased collagenogenesis and elastogenesis. The newly formed elastic fibers appeared morphologically normal, but showed a notable propensity to become calcified. The internal structure of the calcified areas was essentially similar to that of the adjacent uninvolved portions of the elastic fibers. Some of the heavily calcified fibers showed loss of internal structure and fragmentation. These findings support the concept that in PXE, calcification involves morphologically unaltered elastic fibers that subsequently may undergo secondary degenerative changes, such as loss of internal structure and fragmentation.

Calcinosis↗

Medical bioethics and cultural diversity.

Medical bioethics has developed as a new field of study in the US in the past quarter decade, focusing upon the moral principles of autonomy, beneficence, nonmaleficence, and justice. These principles may, however, reflect biases in American culture, rather than a truly universal approach to ethical problems in medicine and health care. Alternative models for bioethics may take the cultural beliefs and practices of different countries more seriously. These different models of bioethics may have important implications for the study of ethical issues in pediatrics. Effective dialogue between America and other countries such as India, especially when focused on particular clinical cases, should expand the understanding of bioethics in those other countries, as well as bringing new light upon American bioethical principles.

Bioethics↗