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Biomedical subjects

H Botto

Publications and source records attributed to H Botto.

At least 55 records · Page 3Linked to original sources

Results of an epidemiological survey using a modified American Urological Association symptom index for benign prostatic hyperplasia in France.

The prevalence of urinary symptoms associated with benign prostatic hyperplasia was studied in a community-based, nationwide, representative sample of 2,011 French men 50 to 80 years old. Symptoms were assessed by the American Urological Association symptom index. After exclusion of patients with prostate cancer, 6.9% of the subjects reported having undergone prostate surgery. Among the surgery-free subjects, nocturia and repeat voiding within 2 hours were the most prevalent symptoms. Based on the American Urological Association symptom index, 18.8% of the men were considered free of urinary symptoms, and 67%, 13% and 1.2%, respectively, ranked between 1 and 7, 8 and 19, and 20 or more. The proportion of men scoring greater than 7 approximately doubled with each decade of age. Our estimation indicated that in 1992 approximately 1.14 million French men had moderate to severe urinary symptoms that were likely to be associated with benign prostatic hyperplasia. Previous studies had yielded higher prevalence estimates, probably due to differences in sampling design and diagnostic criteria.

Aged↗

[Antibiotic prophylaxis in urology. Surgical and endoscopic surgery. Lithotripsy. Transplantation].

The opening of the urinary tract switches surgical and endoscopic urology to the clean contaminated category and therefore for each of them antibiotic prophylaxis has to be considered. Prophylactic antibiotics are only recommended before surgery in patients with sterile urine. Those with infected urine should have curative antibiotics. Prophylactic antibiotics are commonly recommended for transurethral resection of the prostate, transrectal biopsy of the prostate, renal transplant and radical cystectomy with ileal or colonic pouch for urinary diversion. It is worthless in diagnostic cystoscopy. ESWL and scrotal surgery. For other procedures more data are required to conclude.

Anti-Bacterial Agents↗

[Detubulized Z-shaped +enterocystoplasty following total prostato-cystectomy].

After the completion of the radical cystoprostatectomy and a thorough survey of the dissected pelvis, a small bowel segment 50 to 60 cm long is resected, 20 cm proximal to Bauhin's valve. The small bowel resected is left as it is and as we find it, without rotation folding or twist, forming a Z. It is incised at its antimesenteric border and then the ileal plate is formed with running 3/0 vicryl sutures. The urethra is anastomosed in the lower part of the pouch and there after each ureter is implanted directly in a very simple way. The ureteral catheters are brought directly through the anterior abdominal wall lateral to the rextus muscle. When the omentum is large enough and covers all the dissected pelvis, drainage of the operative site will not be necessary.

Cystectomy↗

European collaborative study of antibiotic prophylaxis for transurethral resection of the prostate.

A prospective randomised trial was undertaken in nine European Hospitals to test antibiotic prophylaxis for men undergoing transurethral resection of the prostate. Of the men with no significant growth (< 10(4) cfu ml-1) in their preoperative urine, 247 received a single 1 gram dose of ceftazidime with the induction of anaesthesia, 256 received 1 g daily from the time of induction of anaesthesia until removal of the urethral catheter (but < or = 5 days) and 261 received no prophylaxis. Of evaluable patients 83 (33.9%), 45 (18.7%) and 29 (11.6%) of the no-prophylaxis, single-dose and multidose groups, respectively, developed urinary tract infection in the immediate post-operative period. There were significantly fewer febrile episodes and fewer prescriptions for alternative antibiotics in teh ceftazidime-treated groups. For men developed peri-operative septicaemia and all were in the no-prophylaxis group. We conclude that patients, even those with culture-negative urine pre-operatively, benefit from antibiotic prophylaxis and that antibiotic prophylaxis should be considered for all men undergoing prostatic surgery as a routine procedure.

Aged↗

[Isolated urethral amyloidosis. Case report and review of the literature].

Localised amyloidosis of the urethra is an extremely rare condition and we report one case of induration of the corpus spongiosum. This one is painful and increasingly obstructive. The first differential diagnosis we think about was an inflammatory process or carcinoma. The diagnosis can only be done after biopsies and microscopic observation. Localized amyloidosis must be recognized and this lesion must be locally treated. Since 40 years, about 25 such cases were described.

Adult↗

[Inhibition of bacterial adherence by nitroxoline on cellular adhesion and on urinary catheter surfaces].

Nitroxolin or 5-nitro-8-hydroxyquinoline, used in the treatment of acute or recurrent uncomplicated urinary tract infection (UTI), has been investigated to demonstrate inhibitory effect on bacterial adherence to epithelial cells or solid surfaces. Nitroxolin in vitro and in urine inhibits bacterial adherence of E. coli 38 (MS/MS) on HeLa cells and epithelial cells from human bladder mucosa. In the same conditions, norfloxacin has no effect. Nitroxolin (MIC/8) decreases with a statistically significant difference (p less than 0.001) the bacterial attachment to a urinary catheter surface made in siliconated latex. These results justify the performance of a clinical trial in the prophylaxis of recurrent UTI and the outcome of a bacteriuria associated with indwelling or intermittent bladder catheter.

Anti-Infective Agents, Urinary↗

Complications of the Camey procedure.

Since the authors' first case in 1958, 221 bladder replacements in more than 500 radical cystectomies have been performed in their department. They discuss perioperative complications; postoperative complications including mortality, gastrointestinal problems, urologic problems, and infections; and late complications such as ileal bladder problems, upper urinary tract problems, secondary diversions, and incontinence.

Humans↗