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Biomedical subjects

H Bittard

Publications and source records attributed to H Bittard.

60 records · Page 4Linked to original sources
PubMed1988

[Treatment of Peyronie's disease by a combination of radiotherapy and surgery. Apropos of 51 cases].

93 patients have been treated for Peyronie's disease. 51 patients with severe discomfort received less than 10 grays external radiotherapy. Six months later, 69% of the patients were satisfied. The remaining patients (31%) were operated by a contralateral plication technique. We obtained 65% good results with this technique. This protocol is indicated for patients with severe discomfort with marked deformity.

Adult↗
PubMed1987

[Aneurysm of the abdominal aorta following renal transplantation. Surgical repair with extracorporeal circulation of the graft].

The authors report a case of abdominal aortic aneurysm, revealed three years after a renal transplantation in left hypogastric position. A pump-oxygenator was utilised to protect the renal transplant during the aortic aneurysmectomy. The renal function is normal three years after the aneurysmectomy, and the patient presented not prosthesis infection, despite the corticoid and immunosuppressive treatment.

Aorta, Abdominal↗
PubMedDate not supplied

Influence of cigarette smoking on P53 gene mutations in bladder carcinomas.

BACKGROUND: The aim of this study was to analyse the influence of cigarette smoking on bladder carcinomas. PATIENTS AND METHODS: 98 cases of bladder cancers were examined by single strand conformation polymorphism analysis of exons 5 to 9, followed by DNA direct sequencing. RESULTS: The incidence of p53 gene mutations was not significantly influenced by habitual smoking. However, the p53 mutation spectrum of current smokers differed significantly from the pattern for non-smokers and ex-smokers. Differences between the two populations included multiple mutations in the current-smokers and an absence in non- and ex-smokers (p<0.01), with the predominance of G:C to A:T transitions at CpG sites in non-smokers (60.0%) in comparison with current smokers (7.6%) (p<0.02). Moreover, G:C to T:A and G:C to C:G transversions were found solely in current smokers. CONCLUSION: It would appear that, in current-smokers, the spectrum of p53 gene mutations is related to tobacco-smoke carcinogens and that the habit of smoking increases the extent of DNA damage.

Aged↗