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Biomedical subjects

H Bernhardt

Publications and source records attributed to H Bernhardt.

At least 91 records · Page 5Linked to original sources

[Characterization of the microflora of the small intestine (author's transl)].

Normal and abnormal microflora of the upper small intestine was studied in 356 patients. Low counts are characteristic of normal microbial colonization (eubiosis), changes in quality and/or quantity are pathological (dysbiosis). The latter status is described as overgrowth syndrome. We found some types of dysbiosis. Prevalent was type Dys1 with the highest counts and the greatest variety of bacteria and yeasts. In contrast to this, type Dys2 showed higher germ counts of only one genus like coliforms (Dys2 Coli), streptococci (Dys2 Str.), lactobacilli (Dys2 L.) or yeasts (Dys2 Y.). In dysbiosis, we frequently saw bifidobacterium and bacteroides. Simultaneous sampling from stomach, duodenum, and jejunum indicated different modes of colonization of these parts (oral or fecal type).

Adult↗

[Epidemiological study on the demonstration of precipitating antibodies against Micropolyspora faeni in agricultural workers].

The authors report on the frequency (as determined by the double diffusion test according to Ouchterlony) of circulating precipitating antibodies against thermophil actinomycetes of the genus Micropolyspora faeni in 1666 blood samples from 1376 agricultural workers. These workers belonged to the main professional categories in two districts of the German Democratic Republic and were examined by members of the Research Group on Occupational Medicine in Agriculture of the Ernst Moritz Arndt University during the years 1972-1975. 290 workers were examined twice or three times in a longitudinal study. Positive serological findings were obtained from 5.1% of the subjects under investigation. There were no statistically significant differences with regard to occupational category, sex, age, and season. Nevertheless, there were marked regional differences. The results obtained show that there is no need for special medical supervision of the agricultural workers with regard to thoracic actinomycosis (farmers' lung). Further examinations are of course necessary in case of suspected or clinically manifest affection.

Actinomycetales Infections↗

Therapeutic possibilities in mucosal and organ mycoses.

From the practical experience and from own results of examinations in the therapy of mycoses of mucous membrane and organ resulted the following problems: It is necessary a sufficient concentration of the antimycotic remedy in the place of the growth of the fungus on and in the tissues. It depends on the kind of application, absorptive capacity and compatibility. When pre-disposing factors are present the gastrointestinal tract should be cleaned up as the most important reservoir. Repeated determinations of the causative organisms and tests of the resistance are necessary for therapy.

Antifungal Agents↗

[Resistance problems in mucosal and organ mycoses].

When there is a suspicion of the presence of a mycosis an exact diagnosis is necessary. Apart from the qualitative and quantitative culture to this also belongs an analysis of mycological kinds and a testing of the resistance against antimycotic drugs. The culture of primarily resistant yeast strains and the observation of a change of the mycological causative organisms render this demand urgent.

Antifungal Agents↗

[Incidence and therapy of fungal infections of the efferent urinary pathways].

Manifest infections with fungi of the urinary tract are rare in comparison with bacterial diseases and therefore they are often overseen. When this is concerned a funguria must always be clarified in chronic pyelonephritis. In patients with manifest infections with fungi without pronounced renal insufficiency 5-fluorocytosin is therapeutically very well suited on account of the renal elimination.

Aged↗

Pustular blastomycosis.

A 53-year-old Negro man had North American blastomycosis with acute onset of widespread pustular eruptions. Several tests suggested that the patient might have had a deficiency of delayed hypersensitivity.

Blastomycosis↗

[Intestinal microbial flora and resorption].

An abundant microbial growth in the small intestine is called "overgrowth syndrome". The dysbiosis existing hereby is to be characterized by the prevailing of certain sorts of germs. A series of typical symptoms is explained by the metabolic activity of microorganisms, in which case disturbances of absorption are uppermost. Morphological and histochemical changes of the intestinal mucous membrane as well as disturbances of the bile acid metabolism and the absorption of carbohydrates, fats and vitamin B12 are explained. Finally the author deals with the microflora in conditions of malabsorption.

Animals↗