Search PubMed⌕ Search

Biomedical subjects

H Berger

Publications and source records attributed to H Berger.

At least 271 records · Page 15Linked to original sources
PubMed1982

Verrucous-keratotic variations of malignant melanoma: a clinicopathological study.

Verrucous-keratotic forms of malignant melanoma occur more commonly in women and favor the extremities, but may occur on any anatomic site. Seventy-one percent of such melanomas are situated on the upper and lower extremities. Although two-thirds of these neoplasms can be assigned a histologic pattern according to the classification of Clark, one-third of these melanomas with marked verrucous hyperplasia and hyperkeratosis of the epidermis do not fit into his classification. The neoplastic cells proliferate mostly at the dermo-epidermal interface rather than in the upper reaches of the epidermis. Nodules are practically never formed. Most of the neoplasms are elevated, but like plateaus. They usually show only sparse, mononuclear inflammatory-cell infiltration. Clinically, verrucous-keratotic melanomas resemble one another in that they are small, slightly elevated, devoid of nodules, and without areas of regression. The prognosis of verrucous-keratotic melanomas does not differ from that of nonverrucous melanomas matched for sex, anatomic site, and thickness of the neoplasm.

Female↗
PubMed1981

[Significance of ultrasonography in diagnosing complications following renal transplantations (author's transl)].

Routine follow-up examinations by ultrasonography after renal transplantation were performed in 72 patients from December 1978 until March 1980. The aim of these controls was to recognize local complications in the area or surgery in order to differentiate from a rejection reaction in patients with unclear clinical symptoms. 22 out of 72 patients had local complications. 15 out of those 22 were detected by ultrasound in a state without clinical symptoms, which then could be treated by surgical or urological intervention. We therefore believe that routine follow-up examinations after renal transplantation by ultrasound are indicated in order to recognize local complications. Nuclear procedures should be employed if alteration of blood flow or disturbed function of the transplanted kidney are considered.

Graft Rejection↗
PubMed1981

Urinary excretion of cyclic guanosine 3'.5'-monophosphate in children with malignant tumours.

The present study shows an increased urinary cyclic guanosine 3'.5'-monophosphate (cyclic GMP) excretion rate in children of all age groups bearing malignant tumours or lymphomas. The incidence of increased cyclic GMP excretion was highly significant (79%). Follow-up studies of up to three years have revealed that during periods of remission of malignant disease the urinary cyclic GMP excretion drops to near normal values, whereas recurrences are accompanied by a new increase of cyclic GMP excretion.

Age Factors↗
PubMed1980

Physical measurements on the lipid-containing bacteriophage phi 6.

Bacteriophage phi 6 has been studied by small-angle X-ray scattering intensity-fluctuation spectroscopy, analytical ultracentrifugation, and spectroscopy. The sedimentation coefficient (S(0)0,w) is 375 S, the diffusion coefficient (D(0)20, w) is 2.66 x 10(-8) cm 2/s. Using the Svedberg equation and and an estimate of the partial specific volume, the Mr is 1.49 +/- 0.32 x 10(8). A simple model which describes phi 6, is a central sphere consisting of RNA and protein of radius 330 A and an outer shell of low electron density 40 A thick. The RNA may form five concentric shells in the region r = 140-290 A.

Bacteriophages↗
PubMed1980

[Immunologic studies with the lymphocyte transformation test on the side effects of D-penicillamine therapy in Wilson's disease].

18 patients with Wilson's disease with and without proteinuria and 19 test persons without Wilson's disease were examined for a disturbance of the transformation on account of phythemagglutinin, streptolysin-O and several D-penicillamine preparations by means of the lymphocyte transformation test. Also during the therapy with D-penicillamine was no cause for a disturbed transformation of lymphocytes on the mitogen phythemagglutinin. A cell-conditioned immune reaction to D-penicillamine which could be established by means of the lymphocyte transformation test under the conditions chosen seems to be present in patients with Wilson's disease neither in lacking or insignificant nor in pronounced proteinuria. The increased transformation rates to streptolysin-O in Wilson's disease need confirmation in a larger number of patients. Like the increased spontaneous transformation rates they might refer to an immune-stimulating effect of the D-penicillamine.

Drug Hypersensitivity↗