Giant ossifying fibroma of the maxillary sinus.
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Adult↗
Biomedical subjects
H Berg
Publications and source records attributed to H Berg.
Circadian rhythm in plasma immunoreactive somatomedin-C in children.
Fifteen boys and 27 girls, 11 +/- 2 years of age were studied over a single 24-hour span during the month of June. Statistically significant circadian rhythms of plasma immunoreactive somatomedin-C (SM-C) concentration, immunoreactive growth hormone (hGH) and cortisol concentration were found, which show marked differences in timing. The highest values of somatomedin-C occurred in the early evening hours (acrophase 19:08) in contrast to growth hormone which showed its peak values during the night and cortisol, which peaked in the morning hours. These observations are of interest for the physiologic regulation of somatomedin-C as well as for the clinical evaluation of plasma immunoreactive somatomedin-C concentrations, and for studies of the response of somatomedin-C to hormonal and/or pharmacologic manipulation.
Adolescent↗
Time-varying effects in mice and rats of several synthetic ACTH preparations.
Circadian stage-dependent effects characterize synthetic ACTH 1-17 preparation (HOE 433 = Synchrodyn 1-17), tested in mice and rats, with reference notably to corticosterone and aldosterone production in vitro and to the behavior of rhythms in these two corticoids as an aspect of the adrenal cortical pacemaker of the circadian system. The possibility to advance or delay the rhythm in serum corticosterone by ACTH 1-17 also is demonstrated, as is a differential behavior of the circadian rhythm in serum aldosterone. Differences in timing of circadian corticosterone and aldosterone responses also are described and await further scrutiny for ultradian and infradian (notably circannual) modulation.
Adrenocorticotropic Hormone↗
Circadian-stage-specified effects of a synthetic short chain ACTH-1-17 (HOE 433) on blood leukocytes and corticosterone secretion in mice.
A synthetic short chain ACTH, ACTH-1-17 (HOE 433 = Synchrodyn 1-17), beta-ala1, lys17 corticotropin (1-17)heptadecapeptide-4-N-butylamide, was tested for activity at the anticipated circadian stage of highest adrenal corticosterone responsiveness (22-HALO) in BALB/c mice. Statistically significant dose-response relations were demonstrated both in vitro (corticosterone production by adrenals incubated in Krebs-Ringer solution) and in vivo (increases in the serum corticosterone concentration). Leukocyte counts in mice injected with this ACTH showed statistically significant decreases (as compared to controls) for all kinds of cells except the neutrophil and medium-sized lymphocyte.
Adrenocorticotropic Hormone↗
Chronome of urinary 6-sulfoxy-melatonin excretion, circulating CA125, cancer progression and therapeutic response.
The longitudinal follow-up of a patient with an advanced adenocarcinoma of the ovary sheds new light on the involvement of the pineal in carcinogenesis. The changes in the circadian MESOR of 6-sulfoxy-melatonin following a course of chemotherapy may differ in relation to the success or failure of treatment, yet the MESOR does not correlate with tumor burden assessed by circulating CA125. By contrast, the ratio of circaseptan-to-circadian amplitudes involving two chronome components correlates with the cancer marker. To that extent, the study reveals a critical about 7-day (circaseptan) aspect of the pineal involvement in cancer progression. This information could be exploited in designing schedules of melatonin administration to cancer patients.
Adenocarcinoma↗