Search PubMed⌕ Search

Biomedical subjects

G Wolff

Publications and source records attributed to G Wolff.

At least 253 records · Page 14Linked to original sources
PubMed1975

[Cardiac myxoma (author's transl)].

Between 1965 and 1974 ten patients were operared on for cardiac myxoma. There was a striking variety of signs and symptoms caused by tumour embolization, haemodynamic obstruction, and auto-immunological reactions. The diagnosis should be made early before the occurrence of irreversible complications, especially cerebral embolism. Echocardiography is a simple technique for the detection of atrial myxoma but a negative result does not exclude it, and diagnosis has to be confirmed by angiocardiography. The tumour should be removed as soon as possible after diagnosis. There is danger of tumour embolization in the course of operation. Operative mortality is low in patients with only haemodynamic complications, but in patients with previous cerebral embolism the risk is higher because of possible bleeding in the infarcted areas of the brain resulting from anticoagulation during cardio-pulmonary bypass. Nonetheless, the operation is indicated in all cases. If removal of the myxoma is complete, recurrence is rate and long-term results are good.

Adolescent↗
PubMed1975

Haemodynamic performance and weaning from mechanical ventilation following open-heart surgery.

In 38 patients ventilated after open-heart surgery the effect of a 20 minutes spontaneous breathing period on right atrial pressure (RAP), left atrial pressure (LAP), pulmonary artery pressure (PAP), aortic pressure (AoP), ECG and cardiac index (CI) was monitored. Arterial bloodgas analysis before and during spontaneous breathing ruled out any respiratory failure. The test period of spontaneous breathing provoked an increase in systemic and pulmonary vascular resistance. By this and by a direct aggravation of cardiac failure the work of both ventricles dropped inspite of an increase in enddiastolic ventricular pressure. If these hemodynamic effects of a spontaneous breathing test period are taken as a guide for deciding, if a patient after open-heart surgery is ready for being extubated, the need for reintubation will be extremely rare. The study encourages us to sue mechanical ventilation as an additional instrument for treating heart failure even if no respiratory failure is present.

Heart↗
PubMed1975

Epidural analgesia for the treatment of multiple ribfractures.

Epidural analgesia can be the choice of therapy for all patients with ribfractures and only minor coexisting injuries who are conscious and able to cooperate. In these cases we believe that EA is equivalent or even better than artificial ventilation with all its problems. Generally these patients are far easier to handle and one needs less nursing staff. The dignity of the patients can be maintained and the convalescent time in the intensive care unit is shorter. The criteria for the treatment and for measuring the progress of the patients with multiple ribfractures are discussed.

Anesthesia, Epidural↗
PubMed1975

Comparison of testosterone decanoate, drostanolone and testololactone in disseminated breast cancer--a randomized clinical study.

It can be said that a single hormone therapy with testosterone decanoate, drostanolone, and testosterone gave similar rates of objective responses in metastatic breast cancer. The presented randomized study has been done to prove whether an additional chemotherapy to hormone applications would further improve therapeutic results. During an observation period of 10 to 16 weeks testosterone decanoate and testolactone in combination with cyclophosphamide have more benefitial effects on the patients than drostanolone plus cyclophosphamide. The combination therapy augmented the rate of objective responses from 22-25 percent to 46-55 percent.

Adult↗