[Urethra bifida with preanal opening].
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Biomedical subjects
Publications and source records attributed to G Weisgerber.
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Eight children with pseudo-Hirschsprung's disease are reported. They can be divided into three groups: alimentary ganglioneuromatosis, schwann cell hyperplasia and those with normal appearance by stantard histology. In view of the heterogeneity, histology cannot predict the extent or the prognosis of the disease. Several biopsies at various levels of the alimentary tract and the use of advanced techniques are necessary to assess fully the extent and the type of the lesion and whether it is congenital or acquired. The majority of pseudo-Hirschsprung's disease tend to affect most of alimentary tract, which may lead to the formation of stagnant loops with all their risks. Treatment includes ileostomy, continuous hypoallergenic oral feeding, and manual expression several times a day.
A rare complication of Nissen's operation is described on the basis of four cases. Appearing secondarily, its Clinical signs are hyperperistaltic diarrhea, without bacterial infection and a fall or levelling of the weight curve. Its constant features are:--acceleration of intestinal transit and principally of gastric evacuation;--a characteristic modification of glucose absorption and of the curve of the oral glucose tolerance test compared with the normal intravenous glucose tolerance test. Overload of dissacharides in the intestine and hypervagotony could explain the symptomatology, which responds with difficulty and sometimes only partially to a diet excluding rapidly absorbed surgars. This complication supervenes often in babies operated on at less than six months, and is an indication for post ponement of operation.
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