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Biomedical subjects

G Weisgerber

Publications and source records attributed to G Weisgerber.

At least 55 records · Page 3Linked to original sources

Immediate and long-term results of superior mesenteric vein-inferior vena cava shunt for portal hypertension in children.

Experience with 46 superior mesenteric vein-inferior vena cava shunts in children is reported, with postoperative follow-up of from 2 to 15 yr. The first procedure used as an end-to-side implantation of the vena cava into the right side of the superior mesenteric vein or portal vein after ligating the cava above the iliac vessels (16 cases). In the next 30 children, the vena cava was lengthened using the left or right common iliac vein, thus obtaining better anastomosis and reversed portal flow. Patency may be definitely assumed when the esophageal varices have disappeared within 3 mo; this was observed in 33 children. Results are nearly the same with superior mesenteric vein-inferior vena cava shunt, splenorenal shunt and portacaval shunt when the respective veins of the portal system are more than 1 cm in diameter. When it is less, the superior mesenteric vein-inferior vena cava shunt is more successful than others; this is the case in children under 7 yr of age. No serious trouble was observed after the interruption of the venous circulation of the limbs and pelvis when a superior mesenteric vein-inferior vena cava shunt was performed when the patients were less than 15 yr of age.

Adolescent↗

[Pseudo-tumoral suprarénal-renal dysgenesis (author's transl)].

Intimate fusion of the renal and suprarenal parenchyma, associated with cystic lesions in the zone of tissue juxtaposition, constitutes a form of suprarenal-renal dysgenesis for which the name "dystopia" has been suggested. The distinction must be made from suprarenal-renal adhesions in which a connective tissue barrier between the two parenchymas persists. In this present case, the malformation gave rise to a pseudo-tumoral syndrome of rapid appearance in association with a haemorrhage. Removal of the kidney cannot be avoided in view of the absence of any plane of cleavage with the suprarenal when the suprarenal tumour is removed.

Adrenal Gland Neoplasms↗

Long-term outcome of children with malformative uropathies.

125 cases of severe malformative uropathies, 42 urethral valves (V), 52 degree III vesicoureteral refluxes (VUR), 18 ureterovesical junction stenoses (UVJ), 13 pyeloureteral junction stenoses (PUJ), were studied for a period of 12 years. Based on the hypothesis that prognosis depends on the number of residual nephrons, we used the glomerular filtration rate (GFR) as our basic reference. 62% of our cases had an initial GFR below 50 ml/min/1.73 m2 and 30% had GFR's below 25. Early diagnosis and intervention are important for improvement of GFR. Of the 32% who improved, most were diagnosed in the first year of life, and the exceptional few after 2 years. The extent of initial renal damage is also a limiting factor. Improvement was rarely seen when the initial GFR was below 30 ml/min/1.73 m2. There was a correlation between the initial and final GFR levels. Renal degradation (28% of cases) is most influenced by follow up time. The average age of end stage renal failure (ESRF) onset was 11 years 4 months, but is earlier for V than for VUR. Onset is even earlier when initial damage is more severe. As normal GFR does not exclude later degradation of renal function, another indicator of the risk of this type of evolution should be adopted.

Child↗