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Biomedical subjects

G Weiler

Publications and source records attributed to G Weiler.

125 records · Page 7Linked to original sources
PubMedDate not supplied

[Detection of the cholinesterase inhibitor tacrine and its main metabolites].

Tacrine, a cholinesterase inhibitor for symptomatic treatment of minor to moderate dementia, and its primary metabolites 1-hydroxy-tacrine and 4-hydroxy-tacrine were studied by means of thin-layer chromatography, UV spectroscopy and gas-chromatography/mass spectroscopy. The analytical data (corrected hRf values, UV spectra in solution as well as reflectance spectra, high-pressure liquid chromatography data, GC retention indices and EI mass spectra) including various derivatization methods are described.

Biotransformation↗
PubMedDate not supplied

[Satellite dish as source of electric current. Case report of a fatal and nearly fatal accident at the work site].

The authors report on an initially unrecognized fatal accident caused by electric current at the place of work. The source of the current was a satellite dish which had been improperly connected to an old music box with subsequent connection to the household electrocution system (220 V, 50 Hz). Only when a second nearly fatal accident occurred, proper diagnosis and detection of the uncommon source of the electric current was made.

Accidents, Occupational↗
PubMedDate not supplied

[Case report of pathologic and criminal self injury].

A case of morbid self-violence (Münchhausen Syndrome) leading to death and a case of criminal self-violence (cutaneous emphysema) are reported. The issue of such cases is discussed with regard to the consequences concerning judicial procedure of punishment and insurance.

Adult↗
PubMedDate not supplied

[The hydrodynamic effect of gunshots in cranial explosive shots].

Case report on five fatal gunshot injuries in which discharge of the cranial contents had occurred owing to a skull blast. Despite an appreciable explosive action with destruction of the bony cranium, the brains were not completely destroyed. In analogy to the "Krönlein shot", comparative reflections were made concerning wound ballistics. The case reports show that injury patterns resembling "Krönlein shot" may arise in cranial blast shots in rare cases despite destroyed projectile parts and even in a mouth shot.

Adult↗
PubMedDate not supplied

[Rare suicidal death by electrocution using a timer and vital reaction].

A case of seldom electrocution by using a timer is presented being carried out from a 35 year old woman, who didn't have any professional background. As the fundamental histological result and classical vital reaction a bone marrow embolism was found. Circumstances, results and line of argumentation are presented in detail and discussed.

Adult↗
PubMedDate not supplied

[Discrepancies between police breath alcohol measurements in a field trial and blood alcohol concentration according to BGA guidelines and possible consequences for citizens].

Divergences between breath-alcohol values measured on the occasion of police field experiments and precise blood-alcohol determinations according to guidelines of the German National Institute of Health (BGA) are reported. In 169 selected cases the difference of time between breath analysis and drawing the blood sample was less than 15 minutes. The consequences regarding forensic relevant cut-off values (0.8, 1.1, and 1.6/1000 resp.) are discussed.

Alcohol Drinking↗
PubMedDate not supplied

[Analytical confirmation of error in false positive amphetamine immunoassays and results].

Numerous urine samples were found to be positive when using a new amphetamine immunoassay (AxSYM). Confirmation analysis was carried out in a second laboratory at "reasonable prices" using a simple TLC-method with non specific ninhydrine detection and resulted in many "positive" confirmation findings. The GC/MS analysis clearly indicated the absence of amphetamine derivatives regularly encountered in forensic toxicology. The false-positive immunochemical findings may probably be caused by endogenous substances.

Amphetamine↗
PubMedDate not supplied

[Death in the milieu of homeless persons. A comparative retrospective analysis of an autopsy sample of different regional population structures (Middle Hessia/Hamburg)].

For an evaluation concerning different regional population and community characteristics, 23 fatalities of homeless individuals were selected from the current autopsy series of the Institutes of Legal Medicine of Giessen/Germany and Hamburg/Germany from 1990 to 1996. The outcome of this retrospective analysis enables to overcome the deficiency of knowledge of causes, manners and circumstances of death among homeless individuals.

Accidents↗