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Biomedical subjects

G Vogl

Publications and source records attributed to G Vogl.

At least 37 records · Page 2Linked to original sources
PubMed1989

Doppler and duplex sonography of the cervical arteries and correlations with other examinations. A field study in a population over forty years.

Of the population of a small Tyrolean village, 185 (56%) of the 329 inhabitants over 40 years were investigated by means of Doppler and duplex sonography, electroencephalography (EEG), electrocardiography (ECG), and neurological examination. Four subjects (2%) previously had a transitory ischemic attack (TIA) or stroke in the carotid territory. Sonographically detectable abnormalities in one or more extracranial arteries were present in 42 (23%) persons. Of the 14 subjects with more than slight abnormalities in the common or internal carotid artery two were symptomatic. Two additional cases with TIA or stroke did not show relevant lesions on sonographic examination. The presence of narrowing in the extracranial artery was not related to risk factors (hypertension, smoking, obesity) or abnormalities on ECG and EEG. This study shows 1) that the clinical relevance of ultrasound screening of the carotid arteries in an average population is 15%; 2) that significantly more patients with TIAs or strokes are found in the group with more severe sonographic findings (p = 0.001) than in the group with normal ultrasound results.

Carotid Arteries↗
PubMed1989

Steroid-induced complete remission in a case of primary cerebral non-Hodgkin's lymphoma.

A case of a primary non-Hodgkin's lymphoma of the CNS is reported in which a complete and stable disappearance of an enhancing mass lesion on the CT scan after treatment with dexamethasone was followed by the occurrence of a high-grade malignant lymphoma in the opposite hemisphere 18 months later. The long-lasting and stable remission suggests a direct oncolytic effect of corticosteroids on lymphoma cells. Furthermore, this case illustrates the usefulness of repeated CT examinations in patients with CNS lymphoma and steroid treatment.

Aged↗
PubMed1989

Diesel soot particles catalyze the production of oxy-radicals.

The formation of a strong oxidant similar to the OH. radical is catalyzed by diesel soot particles in the presence of cysteine and hydrogen peroxide or in the presence of light. The oxidant(s) formed causes fragmentation of methylthioketobutyric acid measurable as ethylene release. Furthermore, the model carotenoid crocin is bleached and thiobarbituric-acid-reactive material (malondialdehyde) is produced from linolenic acid. All reactions are inhibited by scavengers (propyl gallate, alpha-tocopherol, diazobicyclooctane) and by catalase. The reactions observed suggest that the toxicity and mutagenicity of diesel soot particles is at least in part due to the formation of reactive oxygen species.

Air Pollutants↗
PubMed1988

Cooperative stimulation by sulfite and crocidolite asbestos fibres of enzyme catalyzed production of reactive oxygen species.

Methylthioketobutyric acid has been used as an indicator for the production of reactive oxygen species during incubation with xanthine oxidase or NADH diaphorase in the presence of an autooxidizable quinone. The production of OH-radical-type oxidants is enhanced in the presence of crocidolite but not by the asbestos types chrysotile or amosite. This activity of crocidolite in the diaphorase system is further stimulated by bisulfite. Crocidolite-dependent ethylene formation from methylthioketo-butyric acid is inhibited by both superoxide dismutase and catalase. In the presence of both crocidolite and bisulfite, however, the inhibition by superoxide dismutase is preserved, but the inhibition by catalase is lost. Since in some respect the NADH-diaphorase quinone system may reflect the situation in the activated macrophage, crocidolite activation may represent a biochemical model system describing potential asbestos toxicity.

Asbestos↗
PubMed1988

[Digital subtraction discography].

Conventional cervical discography was carried out in 25 patients during the period of one year. At the same time, we employed the well known principle of digital subtraction. The results of DSD have been compared with conventional discography. In every case more informative images were obtained despite the use of lower amounts of contrast. The distribution pattern of the reduced amounts of contrast in the disc provides valuable information. In the shoulder region, great improvement in picture quality is possible. For these reasons, the use of digital subtraction for discography is justified.

Humans↗
PubMed1988

[Sonographic determination of the position of the carotid bifurcation as a diagnostic aid in cerebral catheter angiography].

A simple sonographic method is described for demonstrating the position of the carotid bifurcation in the sagittal plane. As a result, it is possible to demonstrate the bifurcation by angiography without overlay, thereby improving the diagnosis of vascular abnormalities. Since non-invasive sonography of the carotid arteries should be carried out before cerebral angiography in any case, the present procedure does not involve any additional effort.

Carotid Arteries↗
PubMed1988

[Radiculography using the digital subtraction technic].

In patients with symptomatic lumbar disc disease, lumbar myelography was performed in combination with the digital subtraction technique. Contrast medium was injected during the digital subtraction procedure, and the following part of the examination was treated conventionally. In all patients the subtracted images were superior for documentation purposes and also for evaluation of the upper lumbar spine. If the contrast medium was injected epidurally, the artifact could be suppressed by the selection of a suitable mask.

Humans↗
PubMed1988

[Value of the dual-energy method in quantitative CT studies of the brain].

Using a dual-energy (DE) method, conventional polyenergetic and monoenergetic beams were used to obtain data in phantom and clinical CT studies and to prove the benefit of this method in quantitative cranial CT. Conventional polyenergetic (85 kVp and 125 kVp) and simulated monoenergetic images were reconstructed from the measurements. The noise in the monoenergetic images was lowest at 72 kVp. The interindividual white-gray differentiation varied less in DE forms than in polyenergetic images, whereas the noise was of the same order of magnitude in both types. As can be derived from our results, DE may be clinically useful in diagnosing abnormal lucency of the white matter in newborn and premature infants.

Adult↗