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Biomedical subjects

G Treister

Publications and source records attributed to G Treister.

At least 91 records · Page 5Linked to original sources

Pars plana approach for pupillary membranes.

Pars plana surgery was performed, using a vitreous infusion suction cutter, for the treatment of after-cataracts, traumatic pupillary membranes, inflammatory pupillary membranes, and varoius pupillary membranes combined with other posterior segment problems. Surgical complications were minimal. A permanent pupillary opening was achieved in all but one case. Visual success was dependent on the underlying disease. One should not operate during active phases of uveitis.

Aged↗

Results of vitrectomy for rare proliferative and hemorrhagic diseases.

We compiled the results of pars plana vitrectomy in rare proliferative and hemorrhagic diseases. In retinal vasculitis of unknown origin (perhaps Eales' disease), six out of seven eyes had visual improvement; in sickle cell disease, two out of three eyes improved. Three eyes with presumed toxocariasis were successfully treated. In retrolental fibroplasia (RLF), only lighter degrees of the cicatricial stage with traction detachments can be treated. Some cases may simulate Coats' disease. There are also cases which simulate the typical picture of RLF, where there is no history of prematurity or oxygen usage. Five patients with RLF were treated, three of these successfully. Cryoglobulinemia (one case) and hereditary hemorrhagic telangiectasia (one case) were successfully treated. Senile macular degeneration can also be an indication for vitrectomy (two out of three eyes were successfully treated).

Adolescent↗

A rapid method for measuring miotic activity of drugs in the intact mouse eye.

A rapid and precise method for evaluating the miotic activity of cholinergic drugs has been developed based on Long's method for measuring the rate of mydriasis. The rate of reversal of mydriasis developed previously in the intact mouse eye by a mild mydriatic (phenycyclidine) is used to evaluate the miotic activity. The method provides a useful tool for measuring and comparing the miotic activity of acetylcholine agonists and cholinesterase inhibitors.

Amides↗

Drugs affecting the cholinergic system in the intact mammalian eye. I. Evaluation of the miotic activity of acetylcholine-like drugs in the mouse eye.

The effect of concentration and pH on the miotic activity of five acetylcholine-like drugs were studied in the intact mouse eye. The data suggests that it is mainly the nonionized form of the drug which contributes to its miotic activity. Acetylcholine-like drugs, degradable by cholinesterases, exert their miotic activity at higher concentrations than do those which are resistant to enzymatic hydrolysis. More active acetylcholine-like drugs appear to be less sensitive to concentration changes.

Acetylcholine↗