Local nasal desensitization in allergic rhinitis.
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Biomedical subjects
Publications and source records attributed to G Taylor.
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By examining serial serum samples from patients undergoing surgical removal of malignant tumours an increased incidence of tumour-specific antibodies has been detected. Antibody responses to tumour neoantigens seem to be transient, and this is held to account for the rarity of detections where a single sample of serum is examined.
In a survey of obstetric anaesthetic services in the United Kingdom questionnaires were sent to 398 hospital maternity units and 347 general-practitioner maternity units, of which 344 and 272 respectively were returned. Many hospitals were unable to provide an anaesthetist for obstetric surgery only, and few consultant anaesthetist sessions were allocated to obstetric surgery, particularly in regional hospitals in England and Wales. Constant supervision of junior anaesthetic staff with under 12 months' experience was lacking in several hospitals. Endotracheal intubation is widely used throughout the United Kingdom. Though regional analgesic techniques are used by most anaesthetists it is impossible to provide a 24-hour regional analgesic service in all but a few hospitals.
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An autoantibody response against a breast carcinoma tumour specific neoantigen is described. The antigen, which was present in 6 of 11 breast carcinomata examined, was shown to have similarities to the T antigen of DNA virus induced animal tumours. In addition a different antigen (or antigenic determinant) was shown to be present in one breast carcinoma. This was not strictly tumour specific, being present in lower concentration in normal breast from the same individual.
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