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Biomedical subjects

G Simu

Publications and source records attributed to G Simu.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

Clinico-morphological correlative aspects in progressive muscular dystrophy.

The author's 15-year experience in the investigation of progressive muscular dystrophy (PMD) is presented. Clinical and paraclinical (biochemical, electromyographical and morphohistochemical) parameters were estimated and correlated in patients with facioscapulohumeral (FSH), Duchenne (D) and limb-girdle (LG) types of muscular dystrophy. The value of each kind of investigation was also estimated in the establishment of the anatomoclinical diagnosis of a degenerative muscular affection.

Adolescent↗
PubMedDate not supplied

Histological aspects of lymphoid organs in chickens with Marek's disease.

Twenty chickens with Marek's disease were studied concerning the histological changes in different organs, especially in lymphoid ones (thymus, bursa of Fabricius, spleen). Neoplastic lesions under the form of a poorly differentiated lymphoma were found in peripheral nerves, gonads, liver, spleen, heart, kidneys, thymus and bursa of Fabricius. In birds without neoplastic transformation of the thymus and bursa, these organs were constantly atrophied following dystrophic phenomena affecting the lymphoid cells, a morphologic expression of the productive type of viral infection. The thymus and also the bursa of Fabricius were neoplastic in three chickens. Marek's disease appears as a very suitable model for the microscopic study of the escalation of the immune response into malignant lymphoma.

Animals↗