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Biomedical subjects

G Schwesinger

Publications and source records attributed to G Schwesinger.

At least 91 records · Page 5Linked to original sources
PubMed1982

[Intracranial metastases in neuroblastomas].

Primary extracranial neuroblastomas frequently metastasize into calvaria, orbita and dura. A direct infiltration is known as secondary metastases to the brain, if the lesion penetrates the bone and dura. Primary metastases to the brain without lesions of the calvaria or dura were observed rarely in extracranial neuroblastomas very interesting with respect to the pathway of metastases. Only a in one of our cases a secondary metastases to the brain could be seen among 21 autopsies. A primary metastases to the brain was diagnosed in a child with a presacral neuroblastoma in the true pelvin. No extracranial metastases could be found, further cases are reviewed from the literature.

Bone Neoplasms↗
PubMed1981

[Unusual dislocation of a pacemaker electrode].

On the basis of an observation is reported on an uncommon dislocation of a separated pacemaker probe into the inside of the heart with a winding-up in the right ventricle. A massive thrombosis with embolus in the lungs developed by a parietal thrombosis in the region of the pacemaker cable. Diagnosing and secondary complications were described and therapeutic and prophylactic measures discussed. Such a complication of the pacemaker therapy must be absolutely excluded in spite of the increasing number of secondary surgical interventions in pacemaker patients.

Aged↗
PubMed1981

[Liver tumours in pregnancy, following previous intake of hormonal contraceptives (author's transl)].

Liver tumours developed in two women during pregnancy which followed discontinuation of hormonal contraception. Liver cell adenoma developed in a secundipara, 24 years of age, and its rupture during puerperium led to death by bleeding, after surgical intervention had failed. Hepatocellular carcinoma was recorded from a secundipara, 22 years of age, and surgically treated, following premature delivery. Problems of diagnosis and the need for interdisciplinary cooperation are discussed and compared with literature data. The pathogenesis of liver tumours in the wake of exogenous hormone inflow and in the context of subsequent pregnancy is another topic of discussion.

Adult↗
PubMed1981

[Occurrence of naphthol-AS-D-chloracetate-esterase-activity in mast cells with special references to cutaneous mastocytoses (author's transl)].

The enzyme naphthol-AS-D-chloracetate esterase (NASDCE) was demonstrated histochemically in mast cells of tissues of laboratory animals and men under normal and pathological conditions using the method after Leder (1964). Investigating the possible action of different fixations as Bouin's and Carnoy's fluid as formaldehyde also cryostate sections were studied for comparison. After tissue fixation the activity of the NASDCE is localized strongly in the granules of mast cells. The type of fixation is without influence on the histochemical reaction and localization. Differences concerning the investigated species could not be demonstrated. In benign neoplasias of mast cells such as diffuse (urticaria pigmentosa) and localized cutaneous mastocytosis as well as benign systemic mastocytosis with skin involvement (Sagher) the granule bound reaction is very intensive. The NASDCE can be recommended as a marker for the microscopical localization of mast cells, especially in the histological diagnosis of their benign and malignant neoplasias.

Animals↗
PubMed1980

[Fibrosarcoma of the right heart. Contribution to the problem of primary heart tumors].

Report on a fibrosarcoma of the right ventricle in a 70-year-old woman. The tumour was diagnosed by autopsy. Clinically were of importance the chronic insufficiency of the right heart, in the ECG the low voltage, a bifascicular block and a subepicardiac lesion in the area of the anterior wall. Roentgenogram of the thorax and the laboratory findings corresponded to a massive cardiac decompensation. The cytology from the effusion of the pericardium which often occurred gives a possibility of making a diagnosis intra vitam, if it is thought of a cardiac tumour.

Aged↗
PubMed1979

[The hypophysis and haemoblastoses].

In necropsies of 165 patients with malignant haemoblastoses, infiltrates in the pituitary were found in 38 cases (23%). The most frequent occurrence was found in lymphoblastic leucosis (33.3%) and in non-Hodgkin lymphomas (29%). Hypophyseal manifestations were found in 21% for myoblastic leucosis and in 5.5% in case of Hodgkin lymphomas. As regards the location, the capsula showed an affection of 55.2%, the anterior and posterior lobes together one of 21.1%, the neurohypophysis one of 15.8% and the anterior lobe one of 7.9%. There are different opinions with regard to the development: exclusively metastatic processes or local formation of the infiltrates. The latter opinion is favoured by the frequent detection of cells of exemplary haemopoiesis between the Dorsum sellae and the outer layer of the hypophyseal capsule (Stratum periostale) in patients without haemoblastosis as well as by the fact that in half of the patients the clinical picture of meningosis leucotica only developed in the stage of haematological full remission, that is, when there were no longer any blastomatous cells in the blood.

Hodgkin Disease↗
PubMed1979

[Metastases in the hypophysis].

Among 1521 malignant extracranial tumours, 64 metastases (4.2%) were found in the pituitary. The most frequent occurrence was found for carcinomas of the breast (21.4%) and for bronchial malignomas (5.9%). A statistically significant difference with regard to the location in the anterior and the posterior lobe was not found in our own patients. A remarkable fact is the high degree of affection of the pituitary gland in case of malignant melanomas.

Breast Neoplasms↗
PubMed1978

[The problem of cardiac metastases].

Report on metastases of the myocardium of a bronchial carcinoma in a 66-year-old woman. On the basis of an own case as well as of literature the author adopts a definite attitude to frequency, localisation and diagnostics of the secondary tumours of the myocardium.

Aged↗
PubMed1978

[Aneurysms of the coronary arteries].

Report on a mycotic and arteriosclerotic aneurysm of the right coronary artery in a 13-year-old girl and a 43-year-old man. With the help of the casuistics and the existing literature the author adopts a definite attitude to genesis, frequency, localisation and complication of the aneurysma.

Adolescent↗